DK0386793T3 - 1alfa-hydroxyvitamin D2 epimer og derivater heraf - Google Patents

1alfa-hydroxyvitamin D2 epimer og derivater heraf

Info

Publication number
DK0386793T3
DK0386793T3 DK90104564.1T DK90104564T DK0386793T3 DK 0386793 T3 DK0386793 T3 DK 0386793T3 DK 90104564 T DK90104564 T DK 90104564T DK 0386793 T3 DK0386793 T3 DK 0386793T3
Authority
DK
Denmark
Prior art keywords
vitamin
derivatives
hydroxyvitamin
1alpha
epimer
Prior art date
Application number
DK90104564.1T
Other languages
English (en)
Inventor
Hector F Deluca
Heinrich K Schnoes
Kato L Perlman
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Application granted granted Critical
Publication of DK0386793T3 publication Critical patent/DK0386793T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK90104564.1T 1989-03-09 1990-03-09 1alfa-hydroxyvitamin D2 epimer og derivater heraf DK0386793T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/321,254 US4973584A (en) 1989-03-09 1989-03-09 Novel 1α-hydroxyvitamin D2 epimer and derivatives

Publications (1)

Publication Number Publication Date
DK0386793T3 true DK0386793T3 (da) 1993-08-02

Family

ID=23249837

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90104564.1T DK0386793T3 (da) 1989-03-09 1990-03-09 1alfa-hydroxyvitamin D2 epimer og derivater heraf

Country Status (15)

Country Link
US (1) US4973584A (da)
EP (1) EP0386793B1 (da)
JP (1) JPH0737443B2 (da)
KR (1) KR950005776B1 (da)
AT (1) ATE90342T1 (da)
AU (1) AU631618B2 (da)
CA (1) CA1335105C (da)
DE (1) DE69001839T2 (da)
DK (1) DK0386793T3 (da)
ES (1) ES2055193T3 (da)
HU (1) HU207040B (da)
IL (1) IL93456A (da)
NZ (1) NZ232735A (da)
RU (1) RU2065851C1 (da)
WO (1) WO1990010619A1 (da)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5030772A (en) * 1990-02-14 1991-07-09 Deluca Hector F Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives
US5260290A (en) * 1990-02-14 1993-11-09 Wisconsin Alumni Research Foundation Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
US5756783A (en) * 1990-09-21 1998-05-26 Bone Care International, Inc. 1α-Hydroxy-24-EPI-vitamin D4
US5786348A (en) * 1991-01-08 1998-07-28 Bone Care International, Inc. Methods for preparation and use of 1α,24(S)-dihydroxy vitamin D2
US6251883B1 (en) 1991-01-08 2001-06-26 Bone Care International, Inc. Methods for preparation and use of 1α,24(S)-dihydroxy vitamin D2
US6538037B2 (en) 1991-01-08 2003-03-25 Bone Care International, Inc. Methods for preparation and use of 1α,24(S)-dihydroxyvitamin D2
US20040009958A1 (en) * 1991-01-08 2004-01-15 Bone Care International, Inc. Methods for preparation and use of 1alpha,24(S)-dihydroxyvitamin D2
US5182396A (en) * 1991-03-29 1993-01-26 Nisshin Flour Milling Co., Ltd. 1-hydroxyvitamin d derivatives
DE69214617T2 (de) * 1991-12-26 1997-05-28 Wisconsin Alumni Res Found 26,27-Dimethylen-1-Alpha, 25-Dihydroxyvitamin-D2 und 26,27-Dihydroxyvitamin-D2 und Verfahren zu ihrer Herstellung
WO1993014763A1 (en) * 1992-01-29 1993-08-05 Lunar Corporation 1α-HYDROXY-24-EPI-VITAMIN D¿4?
US5194431A (en) * 1992-07-08 1993-03-16 Wisconsin Alumni Research Foundation 24-cyclopropane vitamin D derivatives
DE69325253T2 (de) * 1992-08-28 1999-12-02 Bone Care Int Inc 1alpha,24(s)-dihydroxy vitamin d2, seine synthese und verwendung
TW267161B (da) * 1992-11-20 1996-01-01 Hoffmann La Roche
JPH0753384A (ja) * 1993-07-13 1995-02-28 Wisconsin Alumni Res Found ２４−エピ−１α−ヒドロキシビタミンＤ２ を含んでなる骨粗鬆症治療剤
US5565589A (en) * 1993-11-03 1996-10-15 Wisconsin Alumni Research Foundation 17-formyl-5,6-trans-vitamin D compounds
US5373004A (en) * 1993-11-24 1994-12-13 Wisconsin Alumni Research Foundation 26,28-methylene-1α, 25-dihydroxyvitamin D2 compounds
US5661140A (en) * 1994-11-21 1997-08-26 Wisconsin Alumni Research Foundation 18-nor-vitamin D compounds
US5716946A (en) * 1996-02-13 1998-02-10 Wisconsin Alumni Research Foundation Multiple sclerosis treatment
AU1525700A (en) 1998-11-19 2000-06-05 Board Of Trustees Of The University Of Arkansas, The Increasing bone strength with selected bisphosphonates
EP1180035B1 (en) * 1999-04-01 2006-11-02 Johns Hopkins University NON-CALCEMIC, ANTIPROLIFERATIVE, TRANSCRIPTIONALLY ACTIVE SULFUR-CONTAINING ANALOGS OF 1-alpha, 25-DIHYDROXY VITAMIN D3
US6479474B2 (en) 1999-07-08 2002-11-12 Wisconsin Alumni Research Foundation Dietary calcium as a supplement to vitamin D compound treatment of multiple sclerosis
JP2005500402A (ja) * 2001-08-22 2005-01-06 ジョンズ ホプキンス ユニバーシティ １α，２５−ジヒドロキシビタミンＤ３の２４−硫黄置換類縁体
WO2003106411A1 (en) 2002-06-13 2003-12-24 Johns Hopkins University 24-sulfoximine vitamin d3 compounds
AU2003292920A1 (en) 2002-12-18 2004-07-09 Cytochroma Inc. 25-so2-substituted analogs of 1alpha, 25-dihydroxyvitamin d3 (calcitriol)
CA2535185C (en) * 2003-08-20 2013-04-23 Wisconsin Alumni Research Foundation 2-methylene-19-nor-vitamin d2 compounds
KR101991692B1 (ko) 2009-01-27 2019-06-21 베르그 엘엘씨 화학요법과 연관된 부작용을 경감시키기 위한 비타민 ｄ３ 및 이의 유사물
EA201270226A1 (ru) 2009-08-14 2012-09-28 БЕРГ БАЙОСИСТЕМЗ, ЭлЭлСи Витамин d3 и его аналогии для лечения алопеции
EP3003497B1 (en) 2013-05-29 2024-02-14 BPGbio, Inc. Preventing or mitigating chemotherapy induced alopecia using vitamin d

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3907843A (en) * 1974-06-14 1975-09-23 Wisconsin Alumni Res Found 1{60 -Hydroxyergocalciferol and processes for preparing same
US3880894A (en) * 1974-05-24 1975-04-29 Wisconsin Alumni Res Found 1,25-Dihydroxyergocalciferol
AU568549B2 (en) * 1983-05-09 1988-01-07 Wisconsin Alumni Research Foundation Process for the preparation of 1a, 25-dihydroxylated vitamin d2 and related compounds
US4769181A (en) * 1983-11-07 1988-09-06 Wisconsin Alumni Research Foundation 1,25-dihydroxyvitamin D2 compounds
US4588528A (en) * 1984-05-31 1986-05-13 Wisconsin Alumni Research Foundation 1,24-dihydroxy-Δ22 -vitamin D3 and process for preparing same
US4612308A (en) * 1984-11-29 1986-09-16 Hoffmann-La Roche Inc. 25,26-Dehydro-1α,23(S,R)-dihydroxycholecalciferol and its epimers
US4717721A (en) * 1985-05-30 1988-01-05 Howard W. Bremer Sidechain homo-vitamin D compounds with preferential anti-cancer activity

Also Published As

Publication number Publication date
IL93456A0 (en) 1990-11-29
AU5192590A (en) 1990-10-09
JPH03504508A (ja) 1991-10-03
KR920700201A (ko) 1992-02-19
AU631618B2 (en) 1992-12-03
DE69001839D1 (de) 1993-07-15
CA1335105C (en) 1995-04-04
HU207040B (en) 1993-03-01
DE69001839T2 (de) 1993-09-16
ES2055193T3 (es) 1994-08-16
EP0386793B1 (en) 1993-06-09
US4973584A (en) 1990-11-27
RU2065851C1 (ru) 1996-08-27
KR950005776B1 (ko) 1995-05-30
IL93456A (en) 1994-02-27
HU902288D0 (en) 1991-07-29
NZ232735A (en) 1992-07-28
JPH0737443B2 (ja) 1995-04-26
ATE90342T1 (de) 1993-06-15
EP0386793A1 (en) 1990-09-12
WO1990010619A1 (en) 1990-09-20

Similar Documents

Publication Publication Date Title
DK0386793T3 (da) 1alfa-hydroxyvitamin D2 epimer og derivater heraf
OA08581A (en) Treatment of diseases caused by retroviruses.
ZA878877B (en) Treatment of diseases caused by viruses
FR2615097B1 (fr) Impacteur-extracteur de prothese notamment de hanche
FR2617488B1 (fr) Procede de fabrication de structures organisees de collagene, notamment d'origine humaine, et structures organisees de collagene correspondantes
FR2642515B1 (fr) Procede de defense antiaerienne
PT88684A (pt) Metodo de tratamento fosfatidilico de doencas virais
IT1231549B (it) Procedimento per la produzione di semilavorati di cuoio
ZM3087A1 (en) Treatment of diseases caused by retroviruses
ATE70069T1 (de) Antibiotika-a40926-n-acylaminoglycuronyl-aglyko e und antibiotika-a40926-aglykone.
DK0406745T3 (da) Antibiotiske GE 2270 faktorer A1, A2, A3 og H
DK29889D0 (da) Heparinbindende hjernemitogener, deres fremstilling og anvendelse
DK637389D0 (da) Plantebehandlingspraeparat
ES2019053A4 (es) Centro quirurgico modular ambulatorio.
ATE209500T1 (de) Ein neuartiges, antineoplastisches cytokin
FR2637465B1 (fr) Procede de conservation, notamment d'algues fraiches
PT85229A (fr) Procede de preparation des variants de l:alpha-antitrysine humaine glycosylee et vecteurs viral d:expression de l:alpha1-at
DK189285D0 (da) (6,11-dihydro-11-oxodibenz(b,e)oxepinyl)-pentancarboxylsyrer, deres fremstilling og anvendelse
IT8041526A0 (it) Preparazione biologica per la stimolazione dell'attivita' vitale di organismi biologici eprocedimento per la produzione della stessa.
DK552889A (da) Coleopteran-aktive mikroorganismer, beslaegtede insekticide midler og fremgangsmaade til deres fremstilling og anvendelse
FR2643790B1 (fr) Procede de fumigation
NO963789D0 (no) Nye benvekstinduserende preparater
PL268566A1 (en) Biological treatment plant
PL268567A1 (en) Biological treatment plant
IT209939Z2 (it) Apparecchio per abbronzatura artificiale del viso e delle mani a mezzo di lampade autonome.