DK0381958T3 - Fremgangsmåde til fremstilling af en insulinpræcursor - Google Patents

Fremgangsmåde til fremstilling af en insulinpræcursor

Info

Publication number
DK0381958T3
DK0381958T3 DK90100889.6T DK90100889T DK0381958T3 DK 0381958 T3 DK0381958 T3 DK 0381958T3 DK 90100889 T DK90100889 T DK 90100889T DK 0381958 T3 DK0381958 T3 DK 0381958T3
Authority
DK
Denmark
Prior art keywords
insulin
acid
residue
amino
precursor
Prior art date
Application number
DK90100889.6T
Other languages
Danish (da)
English (en)
Inventor
Michael Dr Doerschug
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Application granted granted Critical
Publication of DK0381958T3 publication Critical patent/DK0381958T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/62Insulins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Glass Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Steroid Compounds (AREA)
DK90100889.6T 1989-01-21 1990-01-17 Fremgangsmåde til fremstilling af en insulinpræcursor DK0381958T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3901719A DE3901719A1 (de) 1989-01-21 1989-01-21 Verfahren zur herstellung eines insulinvorlaeufers

Publications (1)

Publication Number Publication Date
DK0381958T3 true DK0381958T3 (da) 1995-12-18

Family

ID=6372512

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90100889.6T DK0381958T3 (da) 1989-01-21 1990-01-17 Fremgangsmåde til fremstilling af en insulinpræcursor

Country Status (17)

Country Link
EP (1) EP0381958B1 (pt)
JP (1) JPH02233699A (pt)
AT (1) ATE126808T1 (pt)
AU (1) AU624894B2 (pt)
CA (1) CA2008245A1 (pt)
DE (2) DE3901719A1 (pt)
DK (1) DK0381958T3 (pt)
ES (1) ES2078249T3 (pt)
FI (1) FI900296A0 (pt)
GR (1) GR3017591T3 (pt)
HU (1) HU208704B (pt)
IE (1) IE900217L (pt)
IL (1) IL93115A (pt)
NO (1) NO178861C (pt)
NZ (1) NZ232178A (pt)
PT (1) PT92907B (pt)
ZA (1) ZA90396B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3901718A1 (de) * 1989-01-21 1990-07-26 Hoechst Ag Verfahren zur renaturierung falscher rekombinanten von insulinvorlaeufern
DE69129747T2 (de) * 1990-09-05 1998-11-12 Southern Cross Biotech Pty. Ltd., Toorak, Victoria In lösung bringen von proteinen in aktiver form
SG46612A1 (en) * 1992-12-02 1998-02-20 Hoechst Ag Process for obtaining proinsulin in processing correctly linked cystine bridges
DE95907193T1 (de) * 1994-12-29 2005-02-10 Savient Pharmaceuticals, Inc. Herstellung von humaninsulin
KR100253916B1 (ko) * 1997-12-29 2000-05-01 김충환 사람 인슐린 전구체의 제조방법
AU2151401A (en) * 1999-12-22 2001-07-03 Novo Nordisk A/S Method for extractive refolding of scrambled single-chain polypeptides

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ196609A (en) * 1980-03-27 1984-02-03 Lilly Co Eli Preparation of proinsulin-like insulin precursors
DE3501641A1 (de) * 1985-01-19 1986-07-24 Hoechst Ag, 6230 Frankfurt Verfahren zur gewinnung von insulin-vorlaeufern aus reaktionsgemischen, die bei der faltung von insulin-vorlaeufern aus den entsprechenden s-sulfonaten anfallen
DE3901718A1 (de) * 1989-01-21 1990-07-26 Hoechst Ag Verfahren zur renaturierung falscher rekombinanten von insulinvorlaeufern

Also Published As

Publication number Publication date
AU624894B2 (en) 1992-06-25
NO178861B (no) 1996-03-11
HUT54389A (en) 1991-02-28
HU208704B (en) 1993-12-28
DE59009540D1 (de) 1995-09-28
ATE126808T1 (de) 1995-09-15
EP0381958B1 (de) 1995-08-23
GR3017591T3 (en) 1995-12-31
ES2078249T3 (es) 1995-12-16
IL93115A0 (en) 1990-11-05
HU900197D0 (en) 1990-03-28
NO900278D0 (no) 1990-01-19
JPH02233699A (ja) 1990-09-17
NO900278L (no) 1990-07-23
NZ232178A (en) 1991-10-25
PT92907B (pt) 1995-12-29
IE900217L (en) 1990-07-21
EP0381958A2 (de) 1990-08-16
FI900296A0 (fi) 1990-01-18
AU4862190A (en) 1990-07-26
NO178861C (no) 1996-06-19
PT92907A (pt) 1990-07-31
CA2008245A1 (en) 1990-07-21
EP0381958A3 (de) 1991-07-24
ZA90396B (en) 1990-09-26
IL93115A (en) 1995-07-31
DE3901719A1 (de) 1990-07-26

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