DK0381219T3 - Gemfibrozilpræparat med modificeret afgivelse - Google Patents

Gemfibrozilpræparat med modificeret afgivelse

Info

Publication number
DK0381219T3
DK0381219T3 DK90102022.2T DK90102022T DK0381219T3 DK 0381219 T3 DK0381219 T3 DK 0381219T3 DK 90102022 T DK90102022 T DK 90102022T DK 0381219 T3 DK0381219 T3 DK 0381219T3
Authority
DK
Denmark
Prior art keywords
granulation
gemfibrozil
pharmaceutically acceptable
finely divided
divided particles
Prior art date
Application number
DK90102022.2T
Other languages
Danish (da)
English (en)
Inventor
Isaac Ghebre-Sellassie
Robert Harry Gordon
Sadath U Khan
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Application granted granted Critical
Publication of DK0381219T3 publication Critical patent/DK0381219T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Dental Preparations (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DK90102022.2T 1989-02-02 1990-02-01 Gemfibrozilpræparat med modificeret afgivelse DK0381219T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/305,082 US4927639A (en) 1989-02-02 1989-02-02 Modified release gemfibrozil composition

Publications (1)

Publication Number Publication Date
DK0381219T3 true DK0381219T3 (da) 1993-06-01

Family

ID=23179253

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90102022.2T DK0381219T3 (da) 1989-02-02 1990-02-01 Gemfibrozilpræparat med modificeret afgivelse

Country Status (21)

Country Link
US (1) US4927639A (de)
EP (1) EP0381219B1 (de)
JP (1) JPH02240017A (de)
KR (1) KR0137268B1 (de)
CN (1) CN1053744A (de)
AT (1) ATE88889T1 (de)
AU (1) AU622751B2 (de)
CA (1) CA2009135A1 (de)
DE (1) DE69001488T2 (de)
DK (1) DK0381219T3 (de)
ES (1) ES2055177T3 (de)
FI (1) FI900491A0 (de)
HU (1) HU204192B (de)
IE (1) IE900371L (de)
IL (1) IL92994A (de)
MY (1) MY104898A (de)
NO (1) NO900484L (de)
NZ (1) NZ232321A (de)
PH (1) PH26317A (de)
PT (1) PT93029A (de)
ZA (1) ZA90776B (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5331756A (en) * 1988-05-04 1994-07-26 Rehrig International, Inc. Basket wall with placard display assembly
EP0462066A1 (de) * 1990-06-15 1991-12-18 Warner-Lambert Company Amorphes Gemfibrozil
EP0462067A1 (de) * 1990-06-15 1991-12-18 Warner-Lambert Company Gemfibrozil-Formulierung
EP0475894A1 (de) * 1990-08-27 1992-03-18 Warner-Lambert Company Verbesserte Gemfibrozil-Formulierungen
US5102668A (en) * 1990-10-05 1992-04-07 Kingaform Technology, Inc. Sustained release pharmaceutical preparation using diffusion barriers whose permeabilities change in response to changing pH
EP0522128B1 (de) * 1991-01-30 1996-01-17 The Wellcome Foundation Limited Wasserlösliche tabletten
US5629016A (en) * 1991-01-30 1997-05-13 Glaxo Wellcome Inc. Water-dispersible tablets
JPH07503236A (ja) * 1991-11-26 1995-04-06 ワーナー−ランバート・コンパニー 制御放出性ジェムフィブロジル剤形の開発のための方法および組成物
US5358723A (en) * 1991-11-26 1994-10-25 Warner-Lambert Company Process and composition for the development of controlled release gemfibrozil dosage form
US5492700A (en) * 1991-11-26 1996-02-20 Warner-Lambert Company Process and composition for the development of controlled release gemfibrozil dosage form
GB9215908D0 (en) * 1992-07-27 1992-09-09 Wellcome Found Water dispersible tablets
US5698226A (en) * 1993-07-13 1997-12-16 Glaxo Wellcome Inc. Water-dispersible tablets
DE4333190C2 (de) * 1993-09-29 1996-05-30 Korsatko Werner Univ Prof Dr E Zerbeißtablette mit verzögerter Wirkstoff-Freisetzung
US5451409A (en) * 1993-11-22 1995-09-19 Rencher; William F. Sustained release matrix system using hydroxyethyl cellulose and hydroxypropyl cellulose polymer blends
US6103262A (en) * 1994-01-27 2000-08-15 G. D. Searle & Company Modified-release metronidazole compositions and methods for making and using same
HU212428B (en) * 1994-05-13 1996-06-28 Egyt Gyogyszervegyeszeti Gyar Process to prepare pharmaceutical compositions containing gemfibrozyl
EP1690531A3 (de) * 1996-09-30 2010-01-20 Alza Corporation Dosierungsform und Verfahren zur Verabreichung von einem Wirkstoff
CA2264852C (en) * 1996-09-30 2005-11-01 Alza Corporation Use of methylphenidate or a pharmaceutically acceptable salt thereof
US6919373B1 (en) 1996-11-12 2005-07-19 Alza Corporation Methods and devices for providing prolonged drug therapy
FR2758459B1 (fr) * 1997-01-17 1999-05-07 Pharma Pass Composition pharmaceutique de fenofibrate presentant une biodisponibilite elevee et son procede de preparation
US7014864B1 (en) 1998-12-18 2006-03-21 Abbott Laboratories Formulations comprising lipid-regulating agents
US6814977B1 (en) 1998-12-18 2004-11-09 Abbott Laboratories Formulations comprising lipid-regulating agents
US6838091B2 (en) 1998-12-18 2005-01-04 Abbott Laboratories Formulations comprising lipid-regulating agents
US6719999B2 (en) 1999-03-31 2004-04-13 Abbott Laboratories Formulations comprising lipid-regulating agents
US6465011B2 (en) 1999-05-29 2002-10-15 Abbott Laboratories Formulations comprising lipid-regulating agents
US6372251B2 (en) 1999-06-11 2002-04-16 Abbott Laboratories Formulations comprising lipid-regulating agents
TW200404544A (en) * 2002-06-17 2004-04-01 Kowa Co Controlled release pharmaceutical composition
US20050265955A1 (en) * 2004-05-28 2005-12-01 Mallinckrodt Inc. Sustained release preparations
EP1753398B1 (de) * 2004-06-10 2018-09-19 Glatt Air Techniques, Inc. Pharmazeutische darreichungsformulierung mit kontrollierter freisetzungsmatrix
FI125478B (fi) * 2010-03-30 2015-10-30 Pertti Neuvonen Farmaseuttinen koostumus, joka sisältää gemfibrotsiiliä ja CYP2C8- ja/tai OATP-substraattilääkettä
JP6364509B2 (ja) * 2014-09-22 2018-07-25 アンフェノール インターコン システムズ、インコーポレイテッド インターポーザ・アセンブリ及び方法
LT4037666T (lt) 2020-12-08 2024-06-10 Ruminant Biotech Corp Limited Medžiagų pristatymo gyvūnams prietaisų ir būdų patobulinimai

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4132753A (en) * 1965-02-12 1979-01-02 American Cyanamid Company Process for preparing oral sustained release granules
US4291016A (en) * 1976-07-27 1981-09-22 Sandoz Ltd. Enteric coated mixture of 4-(2-hydroxy-3-isopropylamino-propoxy) indole and sodium lauryl sulphate
US4195084A (en) * 1977-01-07 1980-03-25 Eli Lilly And Company Taste-stable aqueous pharmaceutical suspension of tall oil sitosterols and a method for the preparation thereof
IT1101649B (it) * 1978-12-15 1985-10-07 Lehner Ag Composizione farmaceutica ad azione prolungata contenente acidi biliari
JPS57171428A (en) * 1981-04-13 1982-10-22 Sankyo Co Ltd Preparation of coated solid preparation
JPS59193831A (ja) * 1983-04-18 1984-11-02 Sankyo Co Ltd 腸溶性製剤の製造法
HU190619B (en) * 1983-11-11 1986-09-29 Bezzegh,Denes,Hu Process for producing tablets with controlled dissolution of active ingredients
CH658188A5 (de) * 1984-03-23 1986-10-31 Ciba Geigy Ag Lagerstabile schnellzerfallende pharmazeutische presslinge.
JPS6144811A (ja) * 1984-08-10 1986-03-04 Ss Pharmaceut Co Ltd 徐放性ジクロフエナクナトリウム製剤
EP0212747B1 (de) * 1985-08-16 1991-04-10 The Procter & Gamble Company Wirkstoffpartikel mit sowohl kontinuierlicher als auch schneller Freisetzung
US4778676A (en) * 1985-12-20 1988-10-18 Warner-Lambert Company Confectionery delivery system for actives
US4716033A (en) * 1986-03-27 1987-12-29 Warner-Lambert Company Medicament adsorbates with surfactant and their preparation
US4816264A (en) * 1986-06-06 1989-03-28 Warner-Lambert Company Sustained release formulations
IT1200178B (it) * 1986-07-23 1989-01-05 Alfa Farmaceutici Spa Formulazioni galeniche a cessione programmata contenenti farmaci ad attivita' antiflogistica
US4814354A (en) * 1986-09-26 1989-03-21 Warner-Lambert Company Lipid regulating agents
EP0276807A3 (de) * 1987-01-27 1988-10-12 Warner-Lambert Company Lipide regulierende Zusammensetzungen

Also Published As

Publication number Publication date
JPH02240017A (ja) 1990-09-25
NO900484D0 (no) 1990-02-01
EP0381219B1 (de) 1993-05-05
CA2009135A1 (en) 1990-08-02
HUT52950A (en) 1990-09-28
HU900638D0 (en) 1990-04-28
IL92994A0 (en) 1990-09-17
US4927639A (en) 1990-05-22
ZA90776B (en) 1991-10-30
NO900484L (no) 1990-08-03
PT93029A (pt) 1990-08-31
MY104898A (en) 1994-06-30
EP0381219A2 (de) 1990-08-08
FI900491A0 (fi) 1990-01-31
HU204192B (en) 1991-12-30
IE900371L (en) 1990-08-02
CN1053744A (zh) 1991-08-14
KR900012604A (ko) 1990-09-01
NZ232321A (en) 1991-02-26
DE69001488T2 (de) 1993-08-26
EP0381219A3 (en) 1990-12-05
IL92994A (en) 1994-04-12
AU4899290A (en) 1990-08-09
ES2055177T3 (es) 1994-08-16
AU622751B2 (en) 1992-04-16
KR0137268B1 (ko) 1998-04-25
PH26317A (en) 1992-04-29
ATE88889T1 (de) 1993-05-15
DE69001488D1 (de) 1993-06-09

Similar Documents

Publication Publication Date Title
DK0381219T3 (da) Gemfibrozilpræparat med modificeret afgivelse
EP0157695B1 (de) Feste Arzneimittel-Darreichungsformen mit gesteuerter Freisetzung auf Basis von Mischungen aus wasserlöslichen nichtionischen Celluloseethern und anionischen Tensiden
EP0322222B1 (de) Hydroxypropylmethylzellulose und Alkalimetall-Carboxylate enthaltende Arzneimittelverabreichungsformen mit verzögerter Freisetzung
KR890004688B1 (ko) 서방형 약제의 담체 조성물
CA1188614A (en) Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose
EP0108218A2 (de) Orale feste Verabreichungsform mit konstanter Wirkstoffabgabe pharmazeutischer Verbindungen, die sehr wasserlöslich sind
KR890001526A (ko) 경구용 서방성 아세트 아미노펜 제형 및 이의 제조방법
DE3877764D1 (de) Ein freifliessendes granulat, enthaltend ibuprofen und ein herstellunsgverfahren.
KR880010757A (ko) 제약정제, 제약과립 및 그의 제조방법
AU7992987A (en) Method and formulation for orally administering bioactive agents to and through the peyer's patch
DE69203488D1 (de) Niedrigdosierte getrocknete pharmazeutische Präparate.
MY104010A (en) Pharmaceutical compositions.
EP0274845A1 (de) Ibuprofen und Codein enthaltende, stabile, feste Arzneimittel
EP0297866A3 (de) Arzneimittel
GEP20033078B (en) Controlled-Release Compositions of Betahistine
CA2361496A1 (en) Ph independent extended release pharmaceutical formulation
JPS5781409A (en) External plaster
JPS625915A (ja) 塩酸ジルチアゼム徐放性製剤及びその製法
ATE110564T1 (de) Pharmazeutische zusammensetzungen mit verzögerter freisetzung zur oralen verabreichung sowie deren herstellungsverfahren.
JPS5344617A (en) Drug composition
HU215191B (hu) Eljárás Levodopa és Carbidopa hatóanyag-kombinációt tartalmazó, szabályozott hatóanyag-leadású, központi dopaminhiányos állapotok kezeléséhez alkalmas orális gyógyszerkészítmény előállítására