DE709456C - Method of stabilizing vitamin C. - Google Patents

Method of stabilizing vitamin C.

Info

Publication number
DE709456C
DE709456C DEG97225D DEG0097225D DE709456C DE 709456 C DE709456 C DE 709456C DE G97225 D DEG97225 D DE G97225D DE G0097225 D DEG0097225 D DE G0097225D DE 709456 C DE709456 C DE 709456C
Authority
DE
Germany
Prior art keywords
vitamin
added
stabilizing vitamin
juice
stabilizing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DEG97225D
Other languages
German (de)
Inventor
Dr Heinrich Gockel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HEINRICH GOCKEL DR
Original Assignee
HEINRICH GOCKEL DR
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by HEINRICH GOCKEL DR filed Critical HEINRICH GOCKEL DR
Priority to DEG97225D priority Critical patent/DE709456C/en
Application granted granted Critical
Publication of DE709456C publication Critical patent/DE709456C/en
Expired legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Non-Alcoholic Beverages (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Description

Verfahren zum Stabilisieren von Vitamin C Das Vitamin C ist bekanntlich in den Naturprodukten und besonders in den daraus hergestellten Extrakten nur beschränkte Zeit haltbar. Es geht zwar häufig zunächst in die biologisch noch wertvolle Dehydroascorbinsäure über, nach mehr oder weniger kurzer Zeit entstehen daraus jedoch biologisch unwirksame Produkte.Method of Stabilizing Vitamin C The vitamin C is well known in the natural products and especially in the extracts made from them only to a limited extent Time durable. It is true that it often first goes into the biologically valuable dehydroascorbic acid over, after a more or less short period of time, however, biologically ineffective ones arise Products.

Es wurde gefunden, daß Schwefelharnstoff, in ganz geringen Mengen den vitamul-C-haltigen Produkten oder Extrakten zugesetzt, das Vitamin C monatelang in fast unveränderter Wirksamkeit erhält, während es ohne diesen Zusatz schon nach kurzer Zeit auf einen Bruchteil seiner Wirksamkeit zurückgeht. Der Zusatz der erforderlichen geringen Mengen Schwefelharnstoff ist unbedenklich. It has been found that urea, in very small amounts added to the vitamul-C-containing products or extracts, the vitamin C for months in almost unchanged effectiveness, while without this addition it is already after decreases to a fraction of its effectiveness in a short time. The addition of the required small amounts of urea is harmless.

Die stabilisierende Wirkung reduzierender bzw. schwefelhaltiger Stoffe, wie Cystein, Cystin, Glutathion, auf das Vitamin C ist bekannt. Thioharnstoff ist leichter und billiger zugänglich als diese Stoffe. The stabilizing effect of reducing or sulfur-containing substances, like cysteine, cystine, glutathione, to which vitamin C is known. Is thiourea easier and cheaper to access than these substances.

Beispilele 1. 11 Zitronensaft mit 280 mg Vitamin C wurde mit 50 mg Thioharnstoff versetzt. Examples 1. 11 lemon juice with 280 mg of vitamin C was made with 50 mg Thiourea added.

Dieser Saft, in geschlossener Flasche auf. bewahrt, enthielt nach 4 Wochen noch 245 mg Vitamin C, während ein gleicher Zitronensaft, mit 50 mg Cystein versetzt, nach 4 Wochen nur noch 65 mg Vitamin C aufwies. This juice, in a closed bottle. preserved, contained after 4 weeks still 245 mg of vitamin C, while the same lemon juice, with 50 mg of cysteine added, after 4 weeks only 65 mg of vitamin C remained.

2. Zu 1 1 Tomatensaft wurden 5 ccm einer 5 0/oigen Thioharnstofflösung in 1o0/ÖigerEssig. säure zugesetzt. Der Vitamin-C-Gehalt des Saftes sank innerhalb von 6 Wochen von - einem Anfangsgehalt von 14,3 mg% auf ,ImgO/o und betrug nach 4Monaten noch 12,4 mg%. Mit 250mg Glutathion als Stabilisator zeigte 1 1 des gleichen Tomatensaftes nach 4 Monaten nur noch einen Vitamin-C-Gehalt von 3,2 mg%. 2. 5 cc of a 5% thiourea solution were added to 1 liter of tomato juice in 1o0 / oil vinegar. acid added. The vitamin C content of the juice decreased within of 6 weeks from - an initial content of 14.3 mg%, ImgO / o and was after 4 months still 12.4 mg%. With 250 mg of glutathione as a stabilizer, 1 1 showed the same Tomato juice only has a vitamin C content of 3.2 mg% after 4 months.

Claims (1)

P A T E N T A N S P R U C H: Verfahren zum Stabilisieren von Vitamin C durch Reduktionsmittel, dadurch gekennzeichnet, daß man Vitamin C enthaltende Zubereitungen mit Schwefelharnstoff oder seinen wasserlöslichen Derivaten versetzt. P A T E N T A N S P R U C H: Method of stabilizing vitamin C by reducing agents, characterized in that one containing vitamin C. Preparations with urea or its water-soluble derivatives added.
DEG97225D 1938-02-11 1938-02-11 Method of stabilizing vitamin C. Expired DE709456C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DEG97225D DE709456C (en) 1938-02-11 1938-02-11 Method of stabilizing vitamin C.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEG97225D DE709456C (en) 1938-02-11 1938-02-11 Method of stabilizing vitamin C.

Publications (1)

Publication Number Publication Date
DE709456C true DE709456C (en) 1941-08-16

Family

ID=7140642

Family Applications (1)

Application Number Title Priority Date Filing Date
DEG97225D Expired DE709456C (en) 1938-02-11 1938-02-11 Method of stabilizing vitamin C.

Country Status (1)

Country Link
DE (1) DE709456C (en)

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