DE69942910D1 - Chemisch modifizierte enzyme und methoden zu ihrer herstellung und zum screeningder enzyme - Google Patents
Chemisch modifizierte enzyme und methoden zu ihrer herstellung und zum screeningder enzymeInfo
- Publication number
- DE69942910D1 DE69942910D1 DE69942910T DE69942910T DE69942910D1 DE 69942910 D1 DE69942910 D1 DE 69942910D1 DE 69942910 T DE69942910 T DE 69942910T DE 69942910 T DE69942910 T DE 69942910T DE 69942910 D1 DE69942910 D1 DE 69942910D1
- Authority
- DE
- Germany
- Prior art keywords
- enzymes
- screening
- preparation
- methods
- chemically modified
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21062—Subtilisin (3.4.21.62)
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
- C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Chemical & Material Sciences (AREA)
- Enzymes And Modification Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Detergent Compositions (AREA)
- Chemical Or Physical Treatment Of Fibers (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7226698P | 1998-01-23 | 1998-01-23 | |
PCT/US1999/001230 WO1999037323A1 (en) | 1998-01-23 | 1999-01-21 | Chemically modified mutant enzymes and methods for producing them and screening them |
Publications (1)
Publication Number | Publication Date |
---|---|
DE69942910D1 true DE69942910D1 (de) | 2010-12-16 |
Family
ID=22106555
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69942910T Expired - Lifetime DE69942910D1 (de) | 1998-01-23 | 1999-01-21 | Chemisch modifizierte enzyme und methoden zu ihrer herstellung und zum screeningder enzyme |
Country Status (9)
Country | Link |
---|---|
US (3) | US6284512B1 (de) |
EP (1) | EP1064019B1 (de) |
JP (1) | JP4475371B2 (de) |
KR (1) | KR20010040398A (de) |
AU (1) | AU2330899A (de) |
CA (1) | CA2327254C (de) |
DE (1) | DE69942910D1 (de) |
DK (1) | DK1064019T3 (de) |
WO (1) | WO1999037323A1 (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1093459B1 (de) | 1998-07-02 | 2008-09-10 | The Governing Council Of The University Of Toronto | Mit einer kohlenhydratgruppe chemisch modifizierte proteine |
ATE433485T1 (de) * | 1998-11-10 | 2009-06-15 | Univ Toronto | Chemisch modifizierte mutante serinhydrolasen |
EP1185302B1 (de) * | 1999-04-28 | 2013-07-24 | Genencor International, Inc. | Spezifischer zielrichtung von katalytische antagoniste und deren verwendungen |
US6627744B2 (en) | 1999-07-02 | 2003-09-30 | Genencor International, Inc. | Synthesis of glycodendrimer reagents |
US7595065B2 (en) * | 2002-06-25 | 2009-09-29 | Wm. Wrigley Jr. Company | Breath freshening and oral cleansing products with synergistic combinations of magnolia bark extract and essential oils |
US8865743B2 (en) | 2006-01-06 | 2014-10-21 | Acelrx Pharmaceuticals, Inc. | Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain |
US9066847B2 (en) | 2007-01-05 | 2015-06-30 | Aceirx Pharmaceuticals, Inc. | Storage and dispensing devices for administration of oral transmucosal dosage forms |
US8252329B2 (en) | 2007-01-05 | 2012-08-28 | Acelrx Pharmaceuticals, Inc. | Bioadhesive drug formulations for oral transmucosal delivery |
US8535714B2 (en) | 2006-01-06 | 2013-09-17 | Acelrx Pharmaceuticals, Inc. | Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain |
US8202535B2 (en) * | 2006-01-06 | 2012-06-19 | Acelrx Pharmaceuticals, Inc. | Small-volume oral transmucosal dosage forms |
US8357114B2 (en) | 2006-01-06 | 2013-01-22 | Acelrx Pharmaceuticals, Inc. | Drug dispensing device with flexible push rod |
US8753308B2 (en) | 2006-01-06 | 2014-06-17 | Acelrx Pharmaceuticals, Inc. | Methods for administering small volume oral transmucosal dosage forms using a dispensing device |
US20070260491A1 (en) * | 2006-05-08 | 2007-11-08 | Pamela Palmer | System for delivery and monitoring of administration of controlled substances |
US8945592B2 (en) | 2008-11-21 | 2015-02-03 | Acelrx Pharmaceuticals, Inc. | Sufentanil solid dosage forms comprising oxygen scavengers and methods of using the same |
US20110091544A1 (en) * | 2009-10-16 | 2011-04-21 | Acelrx Pharmaceuticals, Inc. | Compositions and Methods for Mild Sedation, Anxiolysis and Analgesia in the Procedural Setting |
CN107955721A (zh) | 2010-07-22 | 2018-04-24 | 荷兰联合利华有限公司 | 用于提高清洁的鼠李糖脂和酶的组合物 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5244791A (en) | 1984-05-29 | 1993-09-14 | Genecor International, Inc. | Methods of ester hydrolysis |
US5155033A (en) | 1989-01-06 | 1992-10-13 | Genencor, Inc. | Subtilisins modified at position 225 resulting in a shift in catalytic activity |
DK97190D0 (da) | 1990-04-19 | 1990-04-19 | Novo Nordisk As | Oxidationsstabile detergentenzymer |
US5629173A (en) | 1990-08-09 | 1997-05-13 | Genentech, Inc. | Methods of use of serine protease variants having peptide ligase activity |
EP0542931B1 (de) * | 1990-08-09 | 1999-12-08 | Genentech, Inc. | Serinproteasevarianten mit peptidligase aktivität |
US5316935A (en) | 1992-04-06 | 1994-05-31 | California Institute Of Technology | Subtilisin variants suitable for hydrolysis and synthesis in organic media |
US5837516A (en) | 1995-03-03 | 1998-11-17 | Genentech, Inc. | Subtilisin variants capable of cleaving substrates containing basic residues |
-
1999
- 1999-01-21 US US09/234,956 patent/US6284512B1/en not_active Expired - Lifetime
- 1999-01-21 DK DK99903240.2T patent/DK1064019T3/da active
- 1999-01-21 EP EP99903240A patent/EP1064019B1/de not_active Expired - Lifetime
- 1999-01-21 DE DE69942910T patent/DE69942910D1/de not_active Expired - Lifetime
- 1999-01-21 CA CA002327254A patent/CA2327254C/en not_active Expired - Fee Related
- 1999-01-21 JP JP2000528303A patent/JP4475371B2/ja not_active Expired - Fee Related
- 1999-01-21 AU AU23308/99A patent/AU2330899A/en not_active Abandoned
- 1999-01-21 KR KR1020007008074A patent/KR20010040398A/ko not_active Application Discontinuation
- 1999-01-21 WO PCT/US1999/001230 patent/WO1999037323A1/en not_active Application Discontinuation
-
2001
- 2001-08-24 US US09/938,801 patent/US20020012959A1/en not_active Abandoned
- 2001-08-24 US US09/938,940 patent/US20020015976A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20020015976A1 (en) | 2002-02-07 |
EP1064019A4 (de) | 2003-05-07 |
CA2327254C (en) | 2009-08-11 |
EP1064019A1 (de) | 2001-01-03 |
CA2327254A1 (en) | 1999-07-29 |
EP1064019B1 (de) | 2010-11-03 |
US20020012959A1 (en) | 2002-01-31 |
JP4475371B2 (ja) | 2010-06-09 |
AU2330899A (en) | 1999-08-09 |
US6284512B1 (en) | 2001-09-04 |
DK1064019T3 (da) | 2011-01-24 |
KR20010040398A (ko) | 2001-05-15 |
JP2002500873A (ja) | 2002-01-15 |
WO1999037323A1 (en) | 1999-07-29 |
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