DE69818482D1 - Physiologisch aktive substanzen tkr2449, verfahren zu ihrer herstellung und mikroorganismen - Google Patents

Physiologisch aktive substanzen tkr2449, verfahren zu ihrer herstellung und mikroorganismen

Info

Publication number
DE69818482D1
DE69818482D1 DE69818482T DE69818482T DE69818482D1 DE 69818482 D1 DE69818482 D1 DE 69818482D1 DE 69818482 T DE69818482 T DE 69818482T DE 69818482 T DE69818482 T DE 69818482T DE 69818482 D1 DE69818482 D1 DE 69818482D1
Authority
DE
Germany
Prior art keywords
tkr2449
microorganisms
production
active substances
physiologically active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69818482T
Other languages
English (en)
Other versions
DE69818482T2 (de
Inventor
Kazutoh Takesako
Mitsuhiro Ueno
Naoyuki Awazu
Yoko Uno
Ikunoshin Kato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takara Bio Inc
Original Assignee
Takara Bio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takara Bio Inc filed Critical Takara Bio Inc
Publication of DE69818482D1 publication Critical patent/DE69818482D1/de
Application granted granted Critical
Publication of DE69818482T2 publication Critical patent/DE69818482T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/72—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms
    • C07C235/76—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69818482T 1997-06-09 1998-06-09 Physiologisch aktive substanzen tkr2449, verfahren zu ihrer herstellung und mikroorganismen Expired - Fee Related DE69818482T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP16801197 1997-06-09
JP16801197 1997-06-09
PCT/JP1998/002530 WO1998056755A1 (fr) 1997-06-09 1998-06-09 Substances physiologiquement actives tkr2449, leur procede de preparation et micro-organisme

Publications (2)

Publication Number Publication Date
DE69818482D1 true DE69818482D1 (de) 2003-10-30
DE69818482T2 DE69818482T2 (de) 2004-07-01

Family

ID=15860158

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69818482T Expired - Fee Related DE69818482T2 (de) 1997-06-09 1998-06-09 Physiologisch aktive substanzen tkr2449, verfahren zu ihrer herstellung und mikroorganismen

Country Status (7)

Country Link
US (1) US6303350B1 (de)
EP (1) EP1002793B1 (de)
JP (1) JP4091130B2 (de)
AU (1) AU7552098A (de)
DE (1) DE69818482T2 (de)
ES (1) ES2209140T3 (de)
WO (1) WO1998056755A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1044983B1 (de) 1997-12-22 2007-02-14 Takara Bio Inc. Antibiotikum tkr2999, verfahren zur herstellung desselben sowie mikrobe
JP5042528B2 (ja) * 2003-02-12 2012-10-03 中外製薬株式会社 ウイルス治療薬
MY141506A (en) * 2003-02-12 2010-05-14 Chugai Pharmaceutical Co Ltd Virus therapeutic drug
CN100502853C (zh) * 2003-02-12 2009-06-24 中外制药株式会社 抗病毒药
CN1819990B (zh) 2003-07-09 2010-04-21 中外制药株式会社 具有抗hcv作用的化合物及其制法
JP2006077004A (ja) * 2004-08-11 2006-03-23 Chugai Pharmaceut Co Ltd 抗ｈｃｖ作用を有する化合物およびそれを含む医薬組成物
US8183005B1 (en) 2004-08-11 2012-05-22 Chugai Seiyaku Kabushiki Kaisha Pharmaceutical agents for treating HCV infections
JPWO2006088071A1 (ja) 2005-02-17 2008-07-03 中外製薬株式会社 抗ｈｃｖ作用を有する化合物の製造方法およびその中間体
WO2007000994A1 (ja) * 2005-06-28 2007-01-04 Chugai Seiyaku Kabushiki Kaisha 抗ｈｃｖ作用を有する化合物の製造方法
TW201010692A (en) 2008-06-19 2010-03-16 Public Univ Corp Nagoya City Univ Pharmaceutical composition for treatment or prevention of hbv infection
WO2010061881A1 (ja) 2008-11-26 2010-06-03 中外製薬株式会社 Ｃ型肝炎ウイルスの働きを阻害するオリゴリボヌクレオチドまたはペプチド核酸

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5364948A (en) 1991-08-02 1994-11-15 Merck & Co., Inc. Biologically active compounds isolated from aerobic fermentation of Trichoderma viride
EP0526936A3 (en) 1991-08-02 1993-05-05 Merck & Co. Inc. Cholesterol-lowering agents
AU714072B2 (en) * 1995-06-29 1999-12-16 Banyu Pharmaceutical Co., Ltd. Combinations of inhibitors of farnesyl-protein transferase

Also Published As

Publication number Publication date
US6303350B1 (en) 2001-10-16
WO1998056755A1 (fr) 1998-12-17
ES2209140T3 (es) 2004-06-16
EP1002793A4 (de) 2001-01-31
JP4091130B2 (ja) 2008-05-28
EP1002793B1 (de) 2003-09-24
DE69818482T2 (de) 2004-07-01
EP1002793A1 (de) 2000-05-24
AU7552098A (en) 1998-12-30

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee