DE69938453D1 - Phosphorylierte polymere und deren konjugate - Google Patents

Phosphorylierte polymere und deren konjugate

Info

Publication number
DE69938453D1
DE69938453D1 DE69938453T DE69938453T DE69938453D1 DE 69938453 D1 DE69938453 D1 DE 69938453D1 DE 69938453 T DE69938453 T DE 69938453T DE 69938453 T DE69938453 T DE 69938453T DE 69938453 D1 DE69938453 D1 DE 69938453D1
Authority
DE
Germany
Prior art keywords
conjugates
phosphorylated polymers
phosphorylated
polymers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69938453T
Other languages
English (en)
Inventor
Shalaby Wahba Shalaby
Joel Thomas Corbett
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Poly Med Inc
Original Assignee
Poly Med Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Poly Med Inc filed Critical Poly Med Inc
Application granted granted Critical
Publication of DE69938453D1 publication Critical patent/DE69938453D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/593—Polyesters, e.g. PLGA or polylactide-co-glycolide

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Polyesters Or Polycarbonates (AREA)
DE69938453T 1998-08-10 1999-08-10 Phosphorylierte polymere und deren konjugate Expired - Lifetime DE69938453D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13147298A 1998-08-10 1998-08-10
US9587598P 1998-08-10 1998-08-10
PCT/US1999/018146 WO2000009166A2 (en) 1998-08-10 1999-08-10 Phosphorylated polymers and conjugates thereof

Publications (1)

Publication Number Publication Date
DE69938453D1 true DE69938453D1 (de) 2008-05-15

Family

ID=26790709

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69938453T Expired - Lifetime DE69938453D1 (de) 1998-08-10 1999-08-10 Phosphorylierte polymere und deren konjugate

Country Status (11)

Country Link
EP (1) EP1105161B1 (de)
JP (1) JP2002522596A (de)
AR (1) AR020650A1 (de)
AT (1) ATE390935T1 (de)
AU (1) AU5475599A (de)
CA (1) CA2339143A1 (de)
DE (1) DE69938453D1 (de)
NO (1) NO20010682L (de)
PL (1) PL346758A1 (de)
RU (1) RU2202563C2 (de)
WO (1) WO2000009166A2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7083634B2 (en) * 1998-11-12 2006-08-01 Poly Med Inc Stabilized polyester/cyanoacrylate tissue adhesive formulation
US7109166B1 (en) 1999-08-18 2006-09-19 Societe De Conseils De Recherches Et D'applications Scientifiques, Sas Sustained release formulation of a peptide
EP1348444B1 (de) * 1999-08-18 2006-04-12 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Zusammensetzung mit verzögerter Abgabe in der ein Peptid mit einem Polymer komplexiert ist
PT1204429E (pt) * 1999-08-18 2004-02-27 Conseils De Rec Appl Scient S Formulacao de libertacao prolongada de um peptido
EP2210900A3 (de) 2003-12-16 2010-08-11 Ipsen Pharma GlLP-1-Analoga
EP2650006A1 (de) 2007-09-07 2013-10-16 Ipsen Pharma S.A.S. Analoga von Exendin-4 und Exendin-3
MX339137B (es) 2008-08-07 2016-05-13 Ipsen Pharma Sas Analogos de polipeptidos insulinotropicos dependientes de glucosa (gip) modificados en n terminal.
EP2987805A3 (de) 2008-08-07 2016-04-13 Ipsen Pharma S.A.S. Analoga des glucoseabhängigen insulinotropen polypeptids
JP5571186B2 (ja) 2009-07-22 2014-08-13 イプセン ファルマ ソシエテ パール アクシオン サンプリフィエ ５９位にアミノ酸置換を有するインスリン様増殖因子−１（ｉｇｆ−１）の類似体

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA953456A (en) * 1970-11-30 1974-08-27 John G. Papalos Leather treating composition and process
US4041223A (en) * 1974-08-30 1977-08-09 Nippon Gohsei Kagaku Kogyo Kabushiki Kaisha Process for preparing hydrolyzed ethylene-vinyl acetate copolymer having improved heat stability
JPS59122416A (ja) * 1982-12-29 1984-07-14 Lion Corp 口腔組成物用基材
CH656884A5 (de) * 1983-08-26 1986-07-31 Sandoz Ag Polyolester, deren herstellung und verwendung.
DE3581430D1 (de) * 1984-03-21 1991-02-28 Ici Plc Detergens.
GB8506792D0 (en) * 1985-03-15 1985-04-17 Janssen Pharmaceutica Nv Derivatives of y-cyclodextrin
US5310879A (en) * 1985-04-30 1994-05-10 The Scripps Research Institute Antibodies which immunoreact with lapine lipopolysaccharide binding protein (LBP)
CA1288881C (en) * 1985-10-04 1991-09-10 Ismael Colon Phosphorylated reaction products and compositions incorporating such products
FR2600894B1 (fr) * 1986-07-02 1989-01-13 Centre Nat Rech Scient Conjugues macromoleculaires d'hemoglobine, leur procede de preparation et leurs applications
JPH07116409B2 (ja) * 1987-05-02 1995-12-13 株式会社バイオマテリアルユニバ−ス 外科用接着剤組成物
US5760015A (en) * 1988-01-19 1998-06-02 The Trustees Of The University Of Pennsylvania Cyclodextrin compounds and methods of making and use thereof
US5183809A (en) * 1990-02-15 1993-02-02 The Trustees Of The University Of Pennsylvania/Childrens Hospital Corporation Cyclodextrin polymers and cyclodextrins immobilized on a solid surface
JPH01197500A (ja) * 1988-01-29 1989-08-09 Sumitomo Chem Co Ltd ヒトモノクローナル抗体
DE69030786T2 (de) * 1989-01-27 1998-02-19 Mitsui Toatsu Chemicals Verfahren zur herstellung eines bioverträglichen polyesters
EP0449249B1 (de) * 1990-03-28 1995-06-21 MITSUI TOATSU CHEMICALS, Inc. Auf verölten Flächen haftende Heissschmelzklebmasse und eine rutschstabile Verarbeitungsmethode für metallische Blendbleche
US5143716A (en) * 1991-02-01 1992-09-01 Unger Evan C Phosphorylated sugar alcohols, Mono- and Di-Saccharides as contrast agents for use in magnetic resonance imaging of the gastrointestinal region
KR950002607B1 (ko) * 1991-08-21 1995-03-23 주식회사삼양사 내열성이 우수한 폴리글리콜산의 제조방법
EP0544097A1 (de) * 1991-10-23 1993-06-02 Boehringer Ingelheim Kg Halbfeste Mischungen aus Oligomeren und/oder Polymeren auf der Basis von Milchsäure, Verfahren zur deren Herstellung und deren Verwendung als resorbierbare Implantate
US5672659A (en) * 1993-01-06 1997-09-30 Kinerton Limited Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides
US5635216A (en) * 1993-12-16 1997-06-03 Eli Lilly And Company Microparticle compositions containing peptides, and methods for the preparation thereof
DE4414138A1 (de) * 1994-04-22 1995-10-26 Consortium Elektrochem Ind Acylierte gamma-Cyclodextrine
BR9508139A (pt) * 1994-06-28 1999-11-30 Tri Point Medical Corp Processo, processo de regular uma velocidade de biodegradação in vivo de um polìmero e de unir entre si duas superfìcies in vivo, composição biocompatìvel, adesivo, vedante e implante cirúrgico e sistema de liberação para um agente terapêutico
DE4435082C1 (de) * 1994-09-30 1996-04-18 Fraunhofer Ges Forschung Verfahren zur Herstellung von Celluloseacetatphosphat oder Celluloseacetatsulfat (Celluloseacetatmischester) mit definierter Molekülstruktur und die Verwendung der erhaltenen Celluloseacetatmischester zur Herstellung von Cellulosephosphat bzw. Cellulosesulfat
CA2167455A1 (en) * 1995-01-19 1996-07-20 Kevin Cooper Absorbable polyalkylene diglycolates
GB9524475D0 (en) * 1995-11-30 1996-01-31 Zeneca Ltd Compound preparation and use

Also Published As

Publication number Publication date
AU5475599A (en) 2000-03-06
RU2202563C2 (ru) 2003-04-20
EP1105161B1 (de) 2008-04-02
JP2002522596A (ja) 2002-07-23
ATE390935T1 (de) 2008-04-15
NO20010682L (no) 2001-03-27
EP1105161A2 (de) 2001-06-13
NO20010682D0 (no) 2001-02-09
WO2000009166A3 (en) 2000-11-09
PL346758A1 (en) 2002-02-25
WO2000009166A2 (en) 2000-02-24
AR020650A1 (es) 2002-05-22
CA2339143A1 (en) 2000-02-24

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Legal Events

Date Code Title Description
8332 No legal effect for de