DE69933776D1 - GABA B-REZEPTOR-SUBTYPEN GABA B-R1c UND GABA B-R2 UND DEREN HETERODIMERE - Google Patents
GABA B-REZEPTOR-SUBTYPEN GABA B-R1c UND GABA B-R2 UND DEREN HETERODIMEREInfo
- Publication number
- DE69933776D1 DE69933776D1 DE69933776T DE69933776T DE69933776D1 DE 69933776 D1 DE69933776 D1 DE 69933776D1 DE 69933776 T DE69933776 T DE 69933776T DE 69933776 T DE69933776 T DE 69933776T DE 69933776 D1 DE69933776 D1 DE 69933776D1
- Authority
- DE
- Germany
- Prior art keywords
- gaba
- gabab
- receptor
- heterodimers
- types
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Nutrition Science (AREA)
- Genetics & Genomics (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Hospice & Palliative Care (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Urology & Nephrology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9819420.2A GB9819420D0 (en) | 1998-09-07 | 1998-09-07 | Novel receptor |
GB9819420 | 1998-09-07 | ||
US10367098P | 1998-10-09 | 1998-10-09 | |
US103670P | 1998-10-09 | ||
PCT/GB1999/002918 WO2000014222A2 (en) | 1998-09-07 | 1999-09-03 | GABAB RECEPTOR SUBTYPES GABAB-R1c AND GABAB-R2 AND HETERODIMERS THEREOF |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69933776D1 true DE69933776D1 (de) | 2006-12-07 |
DE69933776T2 DE69933776T2 (de) | 2008-01-03 |
Family
ID=26314336
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69933776T Expired - Lifetime DE69933776T2 (de) | 1998-09-07 | 1999-09-03 | GABA B-REZEPTOR-SUBTYPEN GABA B-R1c UND GABA B-R2 UND DEREN HETERODIMERE |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP1109901B1 (de) |
JP (1) | JP2002524074A (de) |
AT (1) | ATE343634T1 (de) |
AU (1) | AU5639799A (de) |
DE (1) | DE69933776T2 (de) |
ES (1) | ES2275351T3 (de) |
WO (1) | WO2000014222A2 (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1044265A4 (de) * | 1998-08-27 | 2002-10-29 | Synaptic Pharma Corp | Dna, die für ein gaba br2 polypeptid kodiert und deren verwendungen |
JP4581277B2 (ja) * | 2000-03-28 | 2010-11-17 | 味の素株式会社 | 非意図的行動抑制用医薬組成物、および、ランニングニューロン抑制物質の該医薬組成物製造のための使用 |
CA2413451A1 (en) * | 2000-06-19 | 2001-12-27 | Merck Frosst Canada & Co. | Methods of identifying gabab receptor subtype-specific agonists |
US6833441B2 (en) | 2001-08-01 | 2004-12-21 | Abmaxis, Inc. | Compositions and methods for generating chimeric heteromultimers |
US7175983B2 (en) | 2001-11-02 | 2007-02-13 | Abmaxis, Inc. | Adapter-directed display systems |
WO2005026208A2 (en) * | 2003-09-12 | 2005-03-24 | Janssen Pharmaceutica N.V. | Chimeric gabab receptor |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE290079T1 (de) * | 1996-05-30 | 2005-03-15 | Novartis Pharma Gmbh | Metabotropische gaba(b) rezeptoren, rezeptoren- spezifische liganden und deren anwendungen |
WO1999020751A1 (en) * | 1997-10-17 | 1999-04-29 | Synaptic Pharmaceutical Corporation | Dna encoding a gababr2 polypeptide and uses thereof |
EP1027374A1 (de) * | 1997-10-27 | 2000-08-16 | AstraZeneca AB | Nukleotidsequenzen |
CA2321193A1 (en) * | 1998-02-05 | 1999-08-12 | Merck & Co., Inc. | Novel gabab receptor dna sequences |
EP0937777A3 (de) * | 1998-02-20 | 1999-11-24 | Smithkline Beecham Plc | GABA Rezeporen und deren Anwendungen |
WO1999042603A1 (en) * | 1998-02-20 | 1999-08-26 | Smithkline Beecham Corporation | GABAB-R2a, A 7TM RECEPTOR |
WO1999051636A2 (en) * | 1998-04-03 | 1999-10-14 | Nps Pharmaceuticals, Inc. | Gaba b receptor |
IL138747A0 (en) * | 1998-04-03 | 2001-10-31 | Nps Pharma Inc | G-protein fusion receptors and chimeric gabab receptors |
AUPP438498A0 (en) * | 1998-06-29 | 1998-07-23 | Garvan Institute Of Medical Research | Novel Gaba-B receptor |
-
1999
- 1999-09-03 EP EP99943118A patent/EP1109901B1/de not_active Expired - Lifetime
- 1999-09-03 AU AU56397/99A patent/AU5639799A/en not_active Abandoned
- 1999-09-03 ES ES99943118T patent/ES2275351T3/es not_active Expired - Lifetime
- 1999-09-03 WO PCT/GB1999/002918 patent/WO2000014222A2/en active IP Right Grant
- 1999-09-03 JP JP2000568966A patent/JP2002524074A/ja active Pending
- 1999-09-03 AT AT99943118T patent/ATE343634T1/de not_active IP Right Cessation
- 1999-09-03 DE DE69933776T patent/DE69933776T2/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ATE343634T1 (de) | 2006-11-15 |
WO2000014222A3 (en) | 2000-07-06 |
EP1109901B1 (de) | 2006-10-25 |
JP2002524074A (ja) | 2002-08-06 |
EP1109901A2 (de) | 2001-06-27 |
WO2000014222A2 (en) | 2000-03-16 |
AU5639799A (en) | 2000-03-27 |
ES2275351T3 (es) | 2007-06-01 |
DE69933776T2 (de) | 2008-01-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |