DE69933212D1 - Benzocarbazol und indenoindole derivate als östrogene agentien - Google Patents

Benzocarbazol und indenoindole derivate als östrogene agentien

Info

Publication number
DE69933212D1
DE69933212D1 DE69933212T DE69933212T DE69933212D1 DE 69933212 D1 DE69933212 D1 DE 69933212D1 DE 69933212 T DE69933212 T DE 69933212T DE 69933212 T DE69933212 T DE 69933212T DE 69933212 D1 DE69933212 D1 DE 69933212D1
Authority
DE
Germany
Prior art keywords
agents
benzocarbazol
estrogene
indenoindole derivatives
indenoindole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69933212T
Other languages
English (en)
Inventor
Paul Miller
David Collini
Bach Dinh Tran
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
Wyeth LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth LLC filed Critical Wyeth LLC
Application granted granted Critical
Publication of DE69933212D1 publication Critical patent/DE69933212D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/94—[b, c]- or [b, d]-condensed containing carbocyclic rings other than six-membered

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
DE69933212T 1998-05-12 1999-05-11 Benzocarbazol und indenoindole derivate als östrogene agentien Expired - Lifetime DE69933212D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7640798A 1998-05-12 1998-05-12
US7671198A 1998-05-12 1998-05-12
PCT/US1999/010216 WO1999058524A1 (en) 1998-05-12 1999-05-11 Benzocarbazole and indenoindole derived estrogenic agents

Publications (1)

Publication Number Publication Date
DE69933212D1 true DE69933212D1 (de) 2006-10-26

Family

ID=26758069

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69933212T Expired - Lifetime DE69933212D1 (de) 1998-05-12 1999-05-11 Benzocarbazol und indenoindole derivate als östrogene agentien

Country Status (8)

Country Link
EP (1) EP1082319B1 (de)
JP (1) JP2002514641A (de)
CN (1) CN1173973C (de)
AT (1) ATE339415T1 (de)
AU (1) AU3894399A (de)
CA (1) CA2331631A1 (de)
DE (1) DE69933212D1 (de)
WO (1) WO1999058524A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7759498B2 (en) * 2004-09-20 2010-07-20 Janssen Pharmaceutica N.V Tetracyclic heteroatom containing derivatives useful as sex steroid hormone receptor modulators

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3821148A1 (de) * 1988-06-23 1989-12-28 Erwin Von Dr Angerer Aminoalkylindole, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate
CA2135160A1 (en) * 1992-05-08 1993-11-25 Masatoshi Inai Indole derivative
DE4426625A1 (de) * 1994-07-27 1996-03-14 Schering Ag 2-Phenylindole, Verfahren zu deren Herstellung, diese enthaltende pharmazeutische Präparate sowie deren Verwendung zur Herstellung von Arzneimitteln
DE69707189T2 (de) * 1996-04-19 2002-06-20 American Home Products Corp., Madison Östrogene Verbindungen
TW397821B (en) * 1996-04-19 2000-07-11 American Home Produits Corp 3-[4-(2-phenyl-indole-1-ylmethyl)-phenyl]-acrylamides and 2-phenyl-1-[4-(amino-1-yl-alk-1-ynyl)-benzyl]-1H-indol-5-ol as well as pharmaceutical compositions of estrogenic agents thereof

Also Published As

Publication number Publication date
CA2331631A1 (en) 1999-11-18
ATE339415T1 (de) 2006-10-15
EP1082319B1 (de) 2006-09-13
CN1173973C (zh) 2004-11-03
WO1999058524A1 (en) 1999-11-18
CN1308630A (zh) 2001-08-15
AU3894399A (en) 1999-11-29
EP1082319A1 (de) 2001-03-14
JP2002514641A (ja) 2002-05-21

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Legal Events

Date Code Title Description
8332 No legal effect for de