DE69932817D1 - Reinigungsverfahren zur herstellng von mannan bindendem lectin (mbl) und mbl enthaltende medizinische zubereitung - Google Patents

Reinigungsverfahren zur herstellng von mannan bindendem lectin (mbl) und mbl enthaltende medizinische zubereitung

Info

Publication number
DE69932817D1
DE69932817D1 DE69932817T DE69932817T DE69932817D1 DE 69932817 D1 DE69932817 D1 DE 69932817D1 DE 69932817 T DE69932817 T DE 69932817T DE 69932817 T DE69932817 T DE 69932817T DE 69932817 D1 DE69932817 D1 DE 69932817D1
Authority
DE
Germany
Prior art keywords
mbl
product
virus
manufacture
cleaning procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69932817T
Other languages
English (en)
Other versions
DE69932817T2 (de
Inventor
Inga Laursen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Statens Serum Institut SSI
Original Assignee
Statens Serum Institut SSI
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Statens Serum Institut SSI filed Critical Statens Serum Institut SSI
Publication of DE69932817D1 publication Critical patent/DE69932817D1/de
Application granted granted Critical
Publication of DE69932817T2 publication Critical patent/DE69932817T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4726—Lectins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Detergent Compositions (AREA)
DE69932817T 1998-06-10 1999-06-10 Reinigungsverfahren zur herstellng von mannan bindendem lectin (mbl) und mbl enthaltende medizinische zubereitung Expired - Lifetime DE69932817T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DK79398 1998-06-10
DK79398 1998-06-10
US10100798P 1998-09-18 1998-09-18
US101007P 1998-09-18
PCT/DK1999/000319 WO1999064453A1 (en) 1998-06-10 1999-06-10 Purification process for production of mannan-binding lectin and an mbl medicinal product

Publications (2)

Publication Number Publication Date
DE69932817D1 true DE69932817D1 (de) 2006-09-28
DE69932817T2 DE69932817T2 (de) 2007-03-15

Family

ID=26064673

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69932817T Expired - Lifetime DE69932817T2 (de) 1998-06-10 1999-06-10 Reinigungsverfahren zur herstellng von mannan bindendem lectin (mbl) und mbl enthaltende medizinische zubereitung

Country Status (9)

Country Link
EP (1) EP1084143B1 (de)
AT (1) ATE336504T1 (de)
AU (1) AU764066B2 (de)
CA (1) CA2334696C (de)
DE (1) DE69932817T2 (de)
DK (1) DK1084143T3 (de)
ES (1) ES2272067T3 (de)
NZ (1) NZ509089A (de)
WO (1) WO1999064453A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1106846C (zh) * 1997-08-21 2003-04-30 宝酒造株式会社 抗癌症剂
WO2000070043A1 (en) 1999-05-14 2000-11-23 Steffen Thiel Recombinant human mannan-binding lectin
WO2002005833A1 (en) * 2000-07-13 2002-01-24 Natimmune A/S MANNAN-BINDING LECTIN (MBL) TREATMENT OF INFECTIONS IN INDIVIDUALS TREATED WITH TNF-αinhibitors
CN101011573A (zh) 2001-07-23 2007-08-08 纳蒂芒公司 高分子量凝集素的生产
WO2003018617A1 (fr) * 2001-08-31 2003-03-06 Fuso Pharmaceutical Industries, Ltd. Procede de purification de lectine liant le mannose humain, compositions de lectine liant le mannose humain et utilisation medicale de la lectine liant le mannose humain
CN1652813A (zh) * 2002-03-15 2005-08-10 纳蒂芒公司 包含甘露糖结合凝集素的药用组合物
NZ535600A (en) * 2002-04-24 2008-03-28 Queensland Inst Med Res MASP-depleted MBL compositions are superior at activating the complement cascade when compared with MBL purified in complex with its associated MASPs
GB0222014D0 (en) * 2002-09-23 2002-10-30 Leuven K U Res & Dev Mannan-binding lectin
US20090247454A1 (en) * 2004-09-29 2009-10-01 Mellitus, S.L. Method for detecting a predisposition to develop gestational diabetes mellitus and treatment for this disease
WO2006042541A1 (en) * 2004-10-21 2006-04-27 Statens Serum Institut A method comprising nanofiltration to obtain an mbl product safe from infectious agents and the product obtainable by this method
WO2007095154A2 (en) * 2006-02-10 2007-08-23 The Brigham And Women's Hospital, Inc. Lectin complement pathway assays and related compositions and methods

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5270199A (en) * 1987-08-20 1993-12-14 The Children's Medical Center Corporation Human mannose-binding protein

Also Published As

Publication number Publication date
NZ509089A (en) 2002-10-25
DK1084143T3 (da) 2006-12-27
AU764066B2 (en) 2003-08-07
ES2272067T3 (es) 2007-04-16
EP1084143B1 (de) 2006-08-16
WO1999064453A1 (en) 1999-12-16
EP1084143A1 (de) 2001-03-21
AU4134399A (en) 1999-12-30
CA2334696A1 (en) 1999-12-16
DE69932817T2 (de) 2007-03-15
CA2334696C (en) 2014-03-25
ATE336504T1 (de) 2006-09-15

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