DE69932427D1 - Verfahren und testen verwendbar bei der behandlung von alkoholabhängigkeit oder -missbrauch - Google Patents
Verfahren und testen verwendbar bei der behandlung von alkoholabhängigkeit oder -missbrauchInfo
- Publication number
- DE69932427D1 DE69932427D1 DE69932427T DE69932427T DE69932427D1 DE 69932427 D1 DE69932427 D1 DE 69932427D1 DE 69932427 T DE69932427 T DE 69932427T DE 69932427 T DE69932427 T DE 69932427T DE 69932427 D1 DE69932427 D1 DE 69932427D1
- Authority
- DE
- Germany
- Prior art keywords
- abuse
- treatment
- alcohol dependency
- tests useful
- tests
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
- C12Q1/32—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8514898P | 1998-05-12 | 1998-05-12 | |
| US85148P | 1998-05-12 | ||
| PCT/US1999/010339 WO1999058124A1 (en) | 1998-05-12 | 1999-05-12 | Methods and assays useful in the treatment of alcohol dependence or alcohol abuse |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69932427D1 true DE69932427D1 (de) | 2006-08-31 |
| DE69932427T2 DE69932427T2 (de) | 2007-02-22 |
Family
ID=22189761
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69932427T Expired - Lifetime DE69932427T2 (de) | 1998-05-12 | 1999-05-12 | Verfahren und testen verwendbar bei der behandlung von alkoholabhängigkeit oder -missbrauch |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US6121010A (de) |
| EP (1) | EP1077697B1 (de) |
| AU (1) | AU3899199A (de) |
| CA (1) | CA2334830A1 (de) |
| DE (1) | DE69932427T2 (de) |
| WO (1) | WO1999058124A1 (de) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6391310B1 (en) * | 1996-03-13 | 2002-05-21 | Archer Daniels Midland Company | Method of preparing and using isoflavones for the treatment of neurological symptoms |
| US6261565B1 (en) * | 1996-03-13 | 2001-07-17 | Archer Daniels Midland Company | Method of preparing and using isoflavones |
| US6465436B2 (en) | 2000-06-01 | 2002-10-15 | Mclean Hospital | Method for treating alcohol intoxication and alcohol abuse |
| ES2375347T3 (es) | 2000-06-30 | 2012-02-29 | Abdulla Badawy | Métodos y composiciones para el tratamiento del alcoholismo y la dependencia del alcohol. |
| NZ532583A (en) * | 2001-11-05 | 2006-12-22 | Krele Pharmaceuticals | Compositions and methods for increasing compliance using aldehyde dehydrogenase inhibitors ( ALDH ) such as disulfiram and monoamine oxidase B inhibitors ( MAOB ) such as selegiline |
| US6703216B2 (en) | 2002-03-14 | 2004-03-09 | The Regents Of The University Of California | Methods, compositions and apparatuses for detection of gamma-hydroxybutyric acid (GHB) |
| EP1542675A4 (de) * | 2002-06-27 | 2008-11-19 | Endowment For Res In Human Bio | N tzliche verbindungen zur hemmung von aldh |
| EP2345412A1 (de) * | 2005-12-02 | 2011-07-20 | The Johns Hopkins University | Verwendung von hochdosierten Oxazaphosphorinmedikamenten zur Behandlung von Immunstörungen |
| US20080207610A1 (en) * | 2006-07-27 | 2008-08-28 | Jeff Zablocki | Aldh-2 inhibitors in the treatment of addiction |
| US8158810B2 (en) * | 2006-07-27 | 2012-04-17 | Gilead Sciences, Inc. | ALDH-2 inhibitors in the treatment of addiction |
| MX2008015765A (es) | 2006-07-27 | 2009-03-26 | Cv Therapeutics Inc | Inhibidores de aldh-2 en el tratamiento de adiccion. |
| WO2008034074A2 (en) | 2006-09-15 | 2008-03-20 | The Johns Hopkins University | Cyclosphosphamide in combination with anti-idiotypic vaccines |
| WO2008034071A2 (en) | 2006-09-15 | 2008-03-20 | The Johns Hopkins University | Method of identifying patients suitable for high-dose cyclophosphamide treatment |
| WO2008034076A2 (en) | 2006-09-15 | 2008-03-20 | The Johns Hopkins University | Cyclophosphamide in combination with immune therapeutics |
| US7951813B2 (en) | 2007-04-05 | 2011-05-31 | Gilead Sciences, Inc. | Quinazolinone derivatives as ALDH-2 inhibitors |
| KR20100097675A (ko) * | 2007-11-06 | 2010-09-03 | 씨브이 쎄러퓨틱스, 인코포레이티드 | 정신 장애 치료에 있어서의 ａｌｄｈ-2 억제제 |
| WO2009067699A2 (en) * | 2007-11-21 | 2009-05-28 | Accentia Biopharmaceuticals, Inc. | Methods for providing a system of care for an oxazaphosphorine drug regimen |
| US9026372B2 (en) * | 2007-11-21 | 2015-05-05 | Accentia Biopharmaceuticals, Inc. | Methods for providing a system of care for a high-dose oxazaphosphorine drug regimen |
| AU2008348372A1 (en) * | 2008-01-24 | 2009-07-30 | Gilead Palo Alto, Inc. | ALDH-2 inhibitors in the treatment of addiction |
| JP6355921B2 (ja) | 2010-09-01 | 2018-07-11 | トニックス ファーマスーティカルズ, インコーポレイテッドTONIX Pharmaceuticals, Inc. | コカイン嗜癖の治療 |
| TWI567061B (zh) * | 2011-07-01 | 2017-01-21 | 吉李德科學股份有限公司 | 用於治療成癮之化合物 |
| AR087700A1 (es) * | 2011-08-30 | 2014-04-09 | Gilead Sciences Inc | Inhibidores de aldh-2 en el tratamiento de adicciones |
| CN103145673B (zh) | 2011-12-06 | 2015-05-20 | 安徽贝克生物制药有限公司 | 黄豆苷元衍生物及其药学上可接受的盐 |
| WO2023244584A1 (en) | 2022-06-14 | 2023-12-21 | Amygdala Neurosciences, Inc. | Aldh-2 inhibitor compounds and methods of use |
| WO2023244563A1 (en) | 2022-06-14 | 2023-12-21 | Amygdala Neurosciences, Inc. | Aldh-2 inhibitor compounds and methods of use |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5204369A (en) * | 1991-07-01 | 1993-04-20 | The Endowment For Research In Human Biology | Method for the inhibition of aldh-i useful in the treatment of alcohol dependence or alcohol abuse |
| EP1542675A4 (de) * | 2002-06-27 | 2008-11-19 | Endowment For Res In Human Bio | N tzliche verbindungen zur hemmung von aldh |
-
1999
- 1999-05-12 EP EP99921892A patent/EP1077697B1/de not_active Expired - Lifetime
- 1999-05-12 CA CA002334830A patent/CA2334830A1/en not_active Abandoned
- 1999-05-12 WO PCT/US1999/010339 patent/WO1999058124A1/en active IP Right Grant
- 1999-05-12 DE DE69932427T patent/DE69932427T2/de not_active Expired - Lifetime
- 1999-05-12 AU AU38991/99A patent/AU3899199A/en not_active Abandoned
- 1999-05-12 US US09/310,614 patent/US6121010A/en not_active Expired - Lifetime
-
2007
- 2007-07-31 US US11/831,795 patent/US20070270332A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE69932427T2 (de) | 2007-02-22 |
| EP1077697B1 (de) | 2006-07-19 |
| US20070270332A1 (en) | 2007-11-22 |
| EP1077697A1 (de) | 2001-02-28 |
| CA2334830A1 (en) | 1999-11-18 |
| US6121010A (en) | 2000-09-19 |
| WO1999058124A1 (en) | 1999-11-18 |
| AU3899199A (en) | 1999-11-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69932427D1 (de) | Verfahren und testen verwendbar bei der behandlung von alkoholabhängigkeit oder -missbrauch | |
| DE69516152T2 (de) | Zusammensetzungen und verfahren zur anewndung in nachweis von analyten | |
| DE69925266D1 (de) | Verfahren und gerät zur behandlung von herzarhythmie | |
| DE69833071D1 (de) | Blattrahmen-IC-Karte und Verfahren zur Herstellung derselben | |
| DE69534700D1 (de) | Halbleiteranordnungen und verfahren | |
| DE69834401D1 (de) | Businterfacesystem und verfahren | |
| DE69625690T2 (de) | Verfahren zur vorbeugung und behandlung von allergien | |
| ATE351910T1 (de) | Ob-fusionsprotein enthaltende zusammensetzungen und verfahren | |
| DE69830891D1 (de) | Methode und Einrichtung zur Schwingungsdämpfung bei Komponenten von Turbomaschinen | |
| DE69824312D1 (de) | Verfahren und gerät zur beendigung von tachyarrhythmien | |
| DE69608880T2 (de) | Testsatz und verfahren | |
| DE69615355T2 (de) | Verfahren zur schaffung gleichmässiger dicke und zur kapselung von mikromechanischen anordnungen in halbleiterprozessen | |
| DE69840199D1 (de) | Chirurgisches instrument und verfahren | |
| DE69923067D1 (de) | Stentplazierinstrument und verfahren zum beladen | |
| DE69726289D1 (de) | Verfahren und zusammensetzung zur behandlung von substraten bezüglich benetzbarkeit | |
| DE69802229D1 (de) | Kesselstein verhinderndes Mittel und Verfahren zum Verwenden desselben | |
| DE69629054D1 (de) | Abrasiver Gegenstand und Verfahren zu seiner Herstellung. | |
| DE69731700D1 (de) | Arithmetischer Schaltkreis und arithmetisches Verfahren | |
| DE69706043D1 (de) | Integrierte schaltungsschutzanordnung und verfahren | |
| DE19782204T1 (de) | Verlängerungseinrichtung und Verfahren | |
| DE69807021D1 (de) | Verfahren und Geraet zur Implementierung von mehrfachen Ruecksprungstellen | |
| DE69900339D1 (de) | Mittel und Verfahren zur Behandlung von Kunstfasern | |
| DE69838683D1 (de) | Halbleiterbauelement und verfahren zur herstellung | |
| DE69506585D1 (de) | Verfahren und gerät zur prüfung von halbleiterplatten | |
| ATE212855T1 (de) | Verfahren und zusammensetzungen zur behandlung von rheumatoider arthritis |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |