DE69925488D1 - Verwendung von fk506 und verwandten makroliden zur herstellung eines medikaments für die behandlung und vorbeugung von schmerzen - Google Patents

Verwendung von fk506 und verwandten makroliden zur herstellung eines medikaments für die behandlung und vorbeugung von schmerzen

Info

Publication number
DE69925488D1
DE69925488D1 DE69925488T DE69925488T DE69925488D1 DE 69925488 D1 DE69925488 D1 DE 69925488D1 DE 69925488 T DE69925488 T DE 69925488T DE 69925488 T DE69925488 T DE 69925488T DE 69925488 D1 DE69925488 D1 DE 69925488D1
Authority
DE
Germany
Prior art keywords
pain
medicament
prevention
manufacture
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69925488T
Other languages
English (en)
Other versions
DE69925488T2 (de
Inventor
S Kelly
S Mcqueen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astellas Pharma Inc
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE69925488D1 publication Critical patent/DE69925488D1/de
Publication of DE69925488T2 publication Critical patent/DE69925488T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE69925488T 1998-07-06 1999-07-02 Verwendung von fk506 und verwandten makroliden zur herstellung eines medikaments für die behandlung und vorbeugung von schmerzen Expired - Fee Related DE69925488T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9814640 1998-07-06
GBGB9814640.0A GB9814640D0 (en) 1998-07-06 1998-07-06 New use
PCT/JP1999/003602 WO2000001385A1 (en) 1998-07-06 1999-07-02 Use of fk506 and related macrolides in the manufacture of a medicament for treatment or prevention of pain

Publications (2)

Publication Number Publication Date
DE69925488D1 true DE69925488D1 (de) 2005-06-30
DE69925488T2 DE69925488T2 (de) 2005-11-17

Family

ID=10835037

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69925488T Expired - Fee Related DE69925488T2 (de) 1998-07-06 1999-07-02 Verwendung von fk506 und verwandten makroliden zur herstellung eines medikaments für die behandlung und vorbeugung von schmerzen

Country Status (6)

Country Link
EP (1) EP1093371B1 (de)
JP (1) JP2002519378A (de)
DE (1) DE69925488T2 (de)
ES (1) ES2239446T3 (de)
GB (1) GB9814640D0 (de)
WO (1) WO2000001385A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9826656D0 (en) 1998-12-03 1999-01-27 Novartis Ag Organic compounds
EP1594484A2 (de) * 2003-02-17 2005-11-16 Cipla Ltd. Pharmazeutisches pflaster
WO2008083169A2 (en) 2006-12-26 2008-07-10 The Johns Hopkins University Compositions and methods for the treatment of immunologic disorders
AU2007339762B2 (en) 2006-12-27 2011-03-31 The Johns Hopkins University Compositions and methods for treating inflammation and auto-immune diseases
US7989173B2 (en) 2006-12-27 2011-08-02 The Johns Hopkins University Detection and diagnosis of inflammatory disorders
US10265265B2 (en) 2007-03-15 2019-04-23 Drug Delivery Solutions Limited Topical composition
KR20100051829A (ko) 2007-07-31 2010-05-18 리머릭 바이오파르마 인코오포레이티드 인산화된 피론 유사체 및 방법
AU2010286361A1 (en) 2009-08-31 2012-03-15 Amplimmune, Inc. Methods and compositions for the inhibition of transplant rejection
US20130209463A1 (en) 2010-06-30 2013-08-15 Compugen Ltd. Polypeptides and uses thereof as a drug for treatment of multiple sclerosis, rheumatoid arthritis and other autoimmune disorders
EP2726503B1 (de) 2011-06-30 2019-09-04 Compugen Ltd. Polypetide und ihre verwendung zur behandlung von autoimmunerkrankungen und infektionen
WO2013155493A1 (en) 2012-04-12 2013-10-17 Yale University Methods of treating inflammatory and autoimmune diseases and disorders
JP2016505843A (ja) 2012-12-19 2016-02-25 アンプリミューン， インコーポレイテッド Ｂ７−ｈ４特異的抗体、並びにその組成物及び使用方法
CA2912801A1 (en) 2013-05-17 2014-11-20 Medimmune, Llc Receptors for b7-h4
WO2017041053A1 (en) 2015-09-04 2017-03-09 Yale University Polymeric bile acid nanocompositions targeting the pancreas and colon
WO2017070676A1 (en) 2015-10-23 2017-04-27 Massachusetts Instittue Of Technology Nanoparticles comprising a metal core surrounded by a monolayer for lymph node targeting
BR112018069741A2 (pt) 2016-04-04 2019-02-05 Drug Delivery Solutions Ltd composição para aplicação tópica, e, método para fabricar uma composição para aplicação tópica.
KR20240035625A (ko) 2016-09-21 2024-03-15 넥스트큐어 인코포레이티드 Siglec-15를 위한 항체 및 이의 사용 방법
EP3542788A1 (de) 2018-03-19 2019-09-25 MC2 Therapeutics Limited Topische zusammensetzung enthaltend calcipotriol und betamethason dipropionat
EP3782627A4 (de) * 2018-04-17 2021-07-07 Shanghai Tonglian Pharmaceutical Co., Ltd. Zur vorbeugung und/oder behandlung von schmerz und/oder fieber verwendetes arzneimittel, kombinationsprodukt und verwendung davon
WO2019217661A1 (en) 2018-05-09 2019-11-14 Yale University Compositions and systems for ex vivo cell modulation and methods of use thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4859782A (en) * 1986-06-26 1989-08-22 Harbor Branch Oceanographic Institution, Inc. Misakinolide compositions and their derivatives
WO1993007884A1 (en) * 1991-10-25 1993-04-29 Senju Pharmaceutical Co., Ltd. External preparation for treating hemorrhoidal diseases
JPH06345646A (ja) * 1993-06-08 1994-12-20 Fujisawa Pharmaceut Co Ltd ローション剤
DK1147766T3 (da) * 1994-10-26 2005-08-29 Novartis Ag Farmaceutiske sammensætninger

Also Published As

Publication number Publication date
DE69925488T2 (de) 2005-11-17
ES2239446T3 (es) 2005-09-16
EP1093371B1 (de) 2005-05-25
JP2002519378A (ja) 2002-07-02
GB9814640D0 (en) 1998-09-02
EP1093371A1 (de) 2001-04-25
WO2000001385A1 (en) 2000-01-13

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: ASTELLAS PHARMA INC., TOKIO/TOKYO, JP

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee