DE69924118D1 - Verfahren und reagentiensatz zur erkennung von antiviralen wirkstoff resistenzen - Google Patents

Verfahren und reagentiensatz zur erkennung von antiviralen wirkstoff resistenzen

Info

Publication number
DE69924118D1
DE69924118D1 DE69924118T DE69924118T DE69924118D1 DE 69924118 D1 DE69924118 D1 DE 69924118D1 DE 69924118 T DE69924118 T DE 69924118T DE 69924118 T DE69924118 T DE 69924118T DE 69924118 D1 DE69924118 D1 DE 69924118D1
Authority
DE
Germany
Prior art keywords
reverse transcriptase
dna
drug
assay
amplified
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69924118T
Other languages
English (en)
Other versions
DE69924118T2 (de
Inventor
M Heneine
Gerardo Garcia Lerma
Shinji Yamamoto
M Switzer
M Folks
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Us Gov Sec Dis & Prev
Original Assignee
Us Gov Sec Dis & Prev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Gov Sec Dis & Prev filed Critical Us Gov Sec Dis & Prev
Publication of DE69924118D1 publication Critical patent/DE69924118D1/de
Application granted granted Critical
Publication of DE69924118T2 publication Critical patent/DE69924118T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/702—Specific hybridization probes for retroviruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Investigating Or Analyzing Materials By The Use Of Fluid Adsorption Or Reactions (AREA)
  • Saccharide Compounds (AREA)
DE69924118T 1998-06-19 1999-06-18 Verfahren und reagentiensatz zur erkennung von antiviralen wirkstoff resistenzen Expired - Lifetime DE69924118T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9005198P 1998-06-19 1998-06-19
US90051P 1998-06-19
PCT/US1999/013957 WO1999066068A2 (en) 1998-06-19 1999-06-18 Method and kit for detecting resistance to antiviral drugs

Publications (2)

Publication Number Publication Date
DE69924118D1 true DE69924118D1 (de) 2005-04-14
DE69924118T2 DE69924118T2 (de) 2005-12-22

Family

ID=22221041

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69924118T Expired - Lifetime DE69924118T2 (de) 1998-06-19 1999-06-18 Verfahren und reagentiensatz zur erkennung von antiviralen wirkstoff resistenzen

Country Status (6)

Country Link
EP (1) EP1100959B1 (de)
AT (1) ATE290605T1 (de)
CA (1) CA2331260C (de)
DE (1) DE69924118T2 (de)
ES (1) ES2237923T3 (de)
WO (1) WO1999066068A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1160332A1 (de) * 2000-05-30 2001-12-05 Amsterdam Support Diagnostics B.V. Verfahren zum Nachweis von enzymatischer Aktivität oder von Resistenz gegen enzymatiche Inhibitoren
EP1343918A2 (de) * 2000-06-21 2003-09-17 Vigen Laboratories, Inc. Verfahren zur messung viraler reverstranskriptase-akitvität
US20210139947A1 (en) * 2017-07-04 2021-05-13 Cavidi Ab Method for assessing susceptibility of a virus to treatment by measuring enzyme activity and a system therefore
CN116732242A (zh) * 2023-03-16 2023-09-12 赛立安生物技术(广州)有限公司 一种用于检测hiv-1蛋白酶区和逆转录酶区耐药突变的引物组、试剂盒及其检测方法
US11977085B1 (en) 2023-09-05 2024-05-07 Elan Ehrlich Date rape drug detection device and method of using same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993023574A1 (en) * 1992-05-14 1993-11-25 Kozal Michael J Polymerase chain reaction assays for monitoring antiviral therapy
DE69604051T2 (de) * 1995-01-27 1999-12-16 Us Gov Health & Human Serv Verfahren zum sensitiven nachweis von reverser transcriptase
EA005426B1 (ru) * 1996-01-29 2005-02-24 Виролоджик, Инк. Векторы для определения чувствительности вируса к противовирусному лекарственному соединению и способы их применения

Also Published As

Publication number Publication date
WO1999066068A2 (en) 1999-12-23
EP1100959A2 (de) 2001-05-23
ES2237923T3 (es) 2005-08-01
WO1999066068A3 (en) 2001-03-29
CA2331260A1 (en) 1999-12-23
CA2331260C (en) 2008-03-18
ATE290605T1 (de) 2005-03-15
EP1100959B1 (de) 2005-03-09
DE69924118T2 (de) 2005-12-22

Similar Documents

Publication Publication Date Title
DE3751423D1 (de) Primers und Sonden zum Nachweis von Nukleinsäuren.
DE69528706D1 (de) Gekoppeltes ampflikation- und ligationverfahren
DE69840743D1 (de) Nukleinsäure-primer und -sonden zur detektion von hiv-1 und hiv-2
ATE237698T1 (de) Primers und sonden zum nachweis von hiv
DK1427852T3 (da) Enkelnukleotidamplikation og -detektion med polymerase
ATE368129T1 (de) Verfahren unter verwendung ungleicher primer- konzentrationen zur herstellung von nukleinsäure- amplifikaten
ATE92538T1 (de) Verstaerkung und nachweis von nukleinsaeuresequenzen.
WO2002083839A3 (en) P450 single nucleotide polymorphism biochip analysis
KR870007427A (ko) 증폭 및 하이브리드화로 바이러스를 검출하는 방법
ATE427999T1 (de) Erkennung von nukleinsaurepolymorphismen
NZ223039A (en) Methods of sequencing dna using t7 dna polymerase and a kit therefor
DE69622347T2 (de) Oligonukleotid-Primer für Amplifizierung von HCV-Nukleinsäure
DE59606675D1 (de) Verfahren zum nachweis von telomerase-aktivität
DE60219813D1 (de) Test-streife-probesystem und verfahren zur nachweis von spezifischen nukleinsäuresequenzen
ATE368752T1 (de) Verfahren zum nachweis von cytosin-methylierungen
ATE408030T1 (de) Dna-nachweis über einen strangreassoziationskomplex
DE69924118D1 (de) Verfahren und reagentiensatz zur erkennung von antiviralen wirkstoff resistenzen
ATE184055T1 (de) Verfahren zum sensitiven nachweis von reverser transcriptase
BRPI0413825A (pt) detecção molecular multialélica de coronavìrus associado com sars
WO2000066774A3 (en) Improved assay and reagents therefor
ATE197481T1 (de) Verfahren und reagenzien zur typisierung von hla- genen der klasse i
DE69833120D1 (de) Verfahren zur Typisierung des HA-1 Nebenhistokompatibilitätsantigens
Merzouki et al. Accurate and differential quantitation of HIV-1 tat, rev and nef mRNAs by competitive PCR
DE602005024023D1 (de) Nachweis von neisseria gonorrhoeae unter verwendun
Kwoh et al. The use of transcription-based amplification systems in the diagnosis of HIV-1 infections

Legal Events

Date Code Title Description
8364 No opposition during term of opposition