ATE290605T1 - Verfahren und reagentiensatz zur erkennung von antiviralen wirkstoff resistenzen - Google Patents

Verfahren und reagentiensatz zur erkennung von antiviralen wirkstoff resistenzen

Info

Publication number
ATE290605T1
ATE290605T1 AT99930490T AT99930490T ATE290605T1 AT E290605 T1 ATE290605 T1 AT E290605T1 AT 99930490 T AT99930490 T AT 99930490T AT 99930490 T AT99930490 T AT 99930490T AT E290605 T1 ATE290605 T1 AT E290605T1
Authority
AT
Austria
Prior art keywords
reverse transcriptase
dna
drug
assay
amplified
Prior art date
Application number
AT99930490T
Other languages
English (en)
Inventor
Walid M Heneine
Gerardo Garcia Lerma
Shinji Yamamoto
William M Switzer
Thomas M Folks
Original Assignee
Us Gov Health & Human Serv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Gov Health & Human Serv filed Critical Us Gov Health & Human Serv
Application granted granted Critical
Publication of ATE290605T1 publication Critical patent/ATE290605T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/702Specific hybridization probes for retroviruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Investigating Or Analyzing Materials By The Use Of Fluid Adsorption Or Reactions (AREA)
  • Saccharide Compounds (AREA)
AT99930490T 1998-06-19 1999-06-18 Verfahren und reagentiensatz zur erkennung von antiviralen wirkstoff resistenzen ATE290605T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9005198P 1998-06-19 1998-06-19
PCT/US1999/013957 WO1999066068A2 (en) 1998-06-19 1999-06-18 Method and kit for detecting resistance to antiviral drugs

Publications (1)

Publication Number Publication Date
ATE290605T1 true ATE290605T1 (de) 2005-03-15

Family

ID=22221041

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99930490T ATE290605T1 (de) 1998-06-19 1999-06-18 Verfahren und reagentiensatz zur erkennung von antiviralen wirkstoff resistenzen

Country Status (6)

Country Link
EP (1) EP1100959B1 (de)
AT (1) ATE290605T1 (de)
CA (1) CA2331260C (de)
DE (1) DE69924118T2 (de)
ES (1) ES2237923T3 (de)
WO (1) WO1999066068A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1160332A1 (de) * 2000-05-30 2001-12-05 Amsterdam Support Diagnostics B.V. Verfahren zum Nachweis von enzymatischer Aktivität oder von Resistenz gegen enzymatiche Inhibitoren
EP1343918A2 (de) * 2000-06-21 2003-09-17 Vigen Laboratories, Inc. Verfahren zur messung viraler reverstranskriptase-akitvität
US20210139947A1 (en) * 2017-07-04 2021-05-13 Cavidi Ab Method for assessing susceptibility of a virus to treatment by measuring enzyme activity and a system therefore
CN116732242A (zh) * 2023-03-16 2023-09-12 赛立安生物技术(广州)有限公司 一种用于检测hiv-1蛋白酶区和逆转录酶区耐药突变的引物组、试剂盒及其检测方法
US11977085B1 (en) 2023-09-05 2024-05-07 Elan Ehrlich Date rape drug detection device and method of using same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993023574A1 (en) * 1992-05-14 1993-11-25 Kozal Michael J Polymerase chain reaction assays for monitoring antiviral therapy
DE69604051T2 (de) * 1995-01-27 1999-12-16 Us Gov Health & Human Serv Verfahren zum sensitiven nachweis von reverser transcriptase
EA005426B1 (ru) * 1996-01-29 2005-02-24 Виролоджик, Инк. Векторы для определения чувствительности вируса к противовирусному лекарственному соединению и способы их применения

Also Published As

Publication number Publication date
WO1999066068A2 (en) 1999-12-23
EP1100959A2 (de) 2001-05-23
DE69924118D1 (de) 2005-04-14
ES2237923T3 (es) 2005-08-01
WO1999066068A3 (en) 2001-03-29
CA2331260A1 (en) 1999-12-23
CA2331260C (en) 2008-03-18
EP1100959B1 (de) 2005-03-09
DE69924118T2 (de) 2005-12-22

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties