ATE290605T1 - Verfahren und reagentiensatz zur erkennung von antiviralen wirkstoff resistenzen - Google Patents
Verfahren und reagentiensatz zur erkennung von antiviralen wirkstoff resistenzenInfo
- Publication number
- ATE290605T1 ATE290605T1 AT99930490T AT99930490T ATE290605T1 AT E290605 T1 ATE290605 T1 AT E290605T1 AT 99930490 T AT99930490 T AT 99930490T AT 99930490 T AT99930490 T AT 99930490T AT E290605 T1 ATE290605 T1 AT E290605T1
- Authority
- AT
- Austria
- Prior art keywords
- reverse transcriptase
- dna
- drug
- assay
- amplified
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 230000000840 anti-viral effect Effects 0.000 title 1
- 239000003153 chemical reaction reagent Substances 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 5
- 229940079593 drug Drugs 0.000 abstract 5
- 108020004414 DNA Proteins 0.000 abstract 4
- 102100034343 Integrase Human genes 0.000 abstract 4
- 108010092799 RNA-directed DNA polymerase Proteins 0.000 abstract 4
- 238000003556 assay Methods 0.000 abstract 3
- 108020004635 Complementary DNA Proteins 0.000 abstract 2
- 108020001019 DNA Primers Proteins 0.000 abstract 2
- 239000003155 DNA primer Substances 0.000 abstract 2
- 241000710188 Encephalomyocarditis virus Species 0.000 abstract 2
- 239000012472 biological sample Substances 0.000 abstract 2
- 238000010804 cDNA synthesis Methods 0.000 abstract 2
- 239000002299 complementary DNA Substances 0.000 abstract 2
- 238000001514 detection method Methods 0.000 abstract 2
- 239000013615 primer Substances 0.000 abstract 2
- 239000003419 rna directed dna polymerase inhibitor Substances 0.000 abstract 2
- 102000053602 DNA Human genes 0.000 abstract 1
- 239000012807 PCR reagent Substances 0.000 abstract 1
- 238000004458 analytical method Methods 0.000 abstract 1
- 230000002255 enzymatic effect Effects 0.000 abstract 1
- 238000011534 incubation Methods 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000001177 retroviral effect Effects 0.000 abstract 1
- 239000000523 sample Substances 0.000 abstract 1
- 241001430294 unidentified retrovirus Species 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/702—Specific hybridization probes for retroviruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Investigating Or Analyzing Materials By The Use Of Fluid Adsorption Or Reactions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9005198P | 1998-06-19 | 1998-06-19 | |
| PCT/US1999/013957 WO1999066068A2 (en) | 1998-06-19 | 1999-06-18 | Method and kit for detecting resistance to antiviral drugs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE290605T1 true ATE290605T1 (de) | 2005-03-15 |
Family
ID=22221041
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99930490T ATE290605T1 (de) | 1998-06-19 | 1999-06-18 | Verfahren und reagentiensatz zur erkennung von antiviralen wirkstoff resistenzen |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1100959B1 (de) |
| AT (1) | ATE290605T1 (de) |
| CA (1) | CA2331260C (de) |
| DE (1) | DE69924118T2 (de) |
| ES (1) | ES2237923T3 (de) |
| WO (1) | WO1999066068A2 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1160332A1 (de) * | 2000-05-30 | 2001-12-05 | Amsterdam Support Diagnostics B.V. | Verfahren zum Nachweis von enzymatischer Aktivität oder von Resistenz gegen enzymatiche Inhibitoren |
| KR20020047124A (ko) * | 2000-06-21 | 2002-06-21 | 바이젠 레버러토리즈, 인코포레이티드 | 비루스 역전사효소 활성의 측정 |
| US20210139947A1 (en) * | 2017-07-04 | 2021-05-13 | Cavidi Ab | Method for assessing susceptibility of a virus to treatment by measuring enzyme activity and a system therefore |
| CN116732242A (zh) * | 2023-03-16 | 2023-09-12 | 赛立安生物技术(广州)有限公司 | 一种用于检测hiv-1蛋白酶区和逆转录酶区耐药突变的引物组、试剂盒及其检测方法 |
| US11977085B1 (en) | 2023-09-05 | 2024-05-07 | Elan Ehrlich | Date rape drug detection device and method of using same |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU4248593A (en) * | 1992-05-14 | 1993-12-13 | Mark Holodniy | Polymerase chain reaction assays for monitoring antiviral therapy |
| JP4256931B2 (ja) * | 1995-01-27 | 2009-04-22 | アメリカ合衆国 | 逆転写酵素の高感度検出法 |
| KR100537153B1 (ko) * | 1996-01-29 | 2006-12-15 | 바이럴러직, 인코퍼레이티드 | 항바이러스약품감수성및내성그리고항바이러스약물의스크리닝을결정하는방법및조성물 |
-
1999
- 1999-06-18 AT AT99930490T patent/ATE290605T1/de not_active IP Right Cessation
- 1999-06-18 DE DE69924118T patent/DE69924118T2/de not_active Expired - Lifetime
- 1999-06-18 WO PCT/US1999/013957 patent/WO1999066068A2/en not_active Ceased
- 1999-06-18 EP EP99930490A patent/EP1100959B1/de not_active Expired - Lifetime
- 1999-06-18 ES ES99930490T patent/ES2237923T3/es not_active Expired - Lifetime
- 1999-06-18 CA CA002331260A patent/CA2331260C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2331260A1 (en) | 1999-12-23 |
| CA2331260C (en) | 2008-03-18 |
| EP1100959B1 (de) | 2005-03-09 |
| EP1100959A2 (de) | 2001-05-23 |
| DE69924118D1 (de) | 2005-04-14 |
| DE69924118T2 (de) | 2005-12-22 |
| ES2237923T3 (es) | 2005-08-01 |
| WO1999066068A3 (en) | 2001-03-29 |
| WO1999066068A2 (en) | 1999-12-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |