DE69921650D1 - Patientenspezifische dosimetrie - Google Patents

Patientenspezifische dosimetrie

Info

Publication number
DE69921650D1
DE69921650D1 DE69921650T DE69921650T DE69921650D1 DE 69921650 D1 DE69921650 D1 DE 69921650D1 DE 69921650 T DE69921650 T DE 69921650T DE 69921650 T DE69921650 T DE 69921650T DE 69921650 D1 DE69921650 D1 DE 69921650D1
Authority
DE
Germany
Prior art keywords
patient
dose
radiopharmaceutical
specific
disease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69921650T
Other languages
English (en)
Other versions
DE69921650T2 (de
Inventor
M Kroll
A Siegel
L Wahl
R Zasadny
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Michigan
SmithKline Beecham Corp
Original Assignee
Coulter Pharmaceutical Inc
University of Michigan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Coulter Pharmaceutical Inc, University of Michigan filed Critical Coulter Pharmaceutical Inc
Application granted granted Critical
Publication of DE69921650D1 publication Critical patent/DE69921650D1/de
Publication of DE69921650T2 publication Critical patent/DE69921650T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1045Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
    • A61K51/1069Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants the tumor cell being from blood cells, e.g. the cancer being a myeloma

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Optics & Photonics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Radiation-Therapy Devices (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medical Treatment And Welfare Office Work (AREA)
DE69921650T 1998-06-04 1999-06-04 Patientenspezifische dosimetrie Expired - Lifetime DE69921650T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8832798P 1998-06-04 1998-06-04
US88327P 1998-06-04
PCT/US1999/012506 WO1999062565A2 (en) 1998-06-04 1999-06-04 Patient-specific dosimetry

Publications (2)

Publication Number Publication Date
DE69921650D1 true DE69921650D1 (de) 2004-12-09
DE69921650T2 DE69921650T2 (de) 2005-10-20

Family

ID=22210726

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69921650T Expired - Lifetime DE69921650T2 (de) 1998-06-04 1999-06-04 Patientenspezifische dosimetrie

Country Status (12)

Country Link
US (1) US7668662B2 (de)
EP (2) EP1083938B1 (de)
JP (2) JP5099944B2 (de)
AT (1) ATE281184T1 (de)
AU (1) AU766107B2 (de)
CA (1) CA2331064A1 (de)
DE (1) DE69921650T2 (de)
ES (1) ES2233083T3 (de)
HK (1) HK1033553A1 (de)
IL (2) IL140028A0 (de)
NZ (1) NZ508674A (de)
WO (1) WO1999062565A2 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2722568C1 (ru) * 2019-12-31 2020-06-01 Федеральное Государственное Бюджетное Учреждение "Национальный Медицинский Исследовательский Центр Эндокринологии" Министерства Здравоохранения Российской Федерации (Фгбу "Нмиц Эндокринологии" Минздрава России) Способ определения индивидуальной активности 131-йода для проведения радиойодтерапии тиреотоксикоза и прогнозирования времени достижения безопасного уровня активности 131-йода в организме пациента после введения индивидуальной активности 131-йода

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US8489176B1 (en) 2000-08-21 2013-07-16 Spectrum Dynamics Llc Radioactive emission detector equipped with a position tracking system and utilization thereof with medical systems and in medical procedures
US8565860B2 (en) 2000-08-21 2013-10-22 Biosensors International Group, Ltd. Radioactive emission detector equipped with a position tracking system
US8909325B2 (en) 2000-08-21 2014-12-09 Biosensors International Group, Ltd. Radioactive emission detector equipped with a position tracking system and utilization thereof with medical systems and in medical procedures
EP1416297A1 (de) * 2002-10-31 2004-05-06 AEA Technology QSA GmbH Standard Dosis-Kalibrierungsvorrichtung für Beta-Strahler und Verfahren dazu
WO2007010534A2 (en) 2005-07-19 2007-01-25 Spectrum Dynamics Llc Imaging protocols
US7176466B2 (en) 2004-01-13 2007-02-13 Spectrum Dynamics Llc Multi-dimensional image reconstruction
US9040016B2 (en) 2004-01-13 2015-05-26 Biosensors International Group, Ltd. Diagnostic kit and methods for radioimaging myocardial perfusion
US7968851B2 (en) 2004-01-13 2011-06-28 Spectrum Dynamics Llc Dynamic spect camera
US9470801B2 (en) 2004-01-13 2016-10-18 Spectrum Dynamics Llc Gating with anatomically varying durations
US8571881B2 (en) 2004-11-09 2013-10-29 Spectrum Dynamics, Llc Radiopharmaceutical dispensing, administration, and imaging
US8586932B2 (en) 2004-11-09 2013-11-19 Spectrum Dynamics Llc System and method for radioactive emission measurement
US7734331B2 (en) * 2004-03-02 2010-06-08 General Electric Company Systems, methods and apparatus for preparation, delivery and monitoring of radioisotopes in positron emission tomography
EP1778957A4 (de) 2004-06-01 2015-12-23 Biosensors Int Group Ltd Optimierung der messung radioaktiver strahlung an besonderen körperstrukturen
US9943274B2 (en) 2004-11-09 2018-04-17 Spectrum Dynamics Medical Limited Radioimaging using low dose isotope
US8423125B2 (en) 2004-11-09 2013-04-16 Spectrum Dynamics Llc Radioimaging
EP1827505A4 (de) 2004-11-09 2017-07-12 Biosensors International Group, Ltd. Radiodarstellung
US9316743B2 (en) 2004-11-09 2016-04-19 Biosensors International Group, Ltd. System and method for radioactive emission measurement
US8615405B2 (en) 2004-11-09 2013-12-24 Biosensors International Group, Ltd. Imaging system customization using data from radiopharmaceutical-associated data carrier
US20060127311A1 (en) * 2004-11-17 2006-06-15 Duke University Radiation dosimetry and blocking antibodies and methods and uses therefor in the treatment of cancer
WO2008059489A2 (en) 2006-11-13 2008-05-22 Spectrum Dynamics Llc Radioimaging applications of and novel formulations of teboroxime
US8834338B2 (en) * 2005-02-10 2014-09-16 Snip Holdings, Inc. Dosimetry implant for treating restenosis and hyperplasia
US8114264B2 (en) * 2005-02-10 2012-02-14 Brookhaven Science Associates Method of electroplating a conversion electron emitting source on implant
US8837793B2 (en) 2005-07-19 2014-09-16 Biosensors International Group, Ltd. Reconstruction stabilizer and active vision
EP1922689A4 (de) * 2005-08-11 2010-05-05 Opto Global Holdings Pty Ltd Verfahren und system zur steuerung einer therapeutischen prozedur
CN101247755B (zh) * 2005-08-25 2018-04-24 皇家飞利浦电子股份有限公司 用于针对性医疗的基于图像的设备
US8894974B2 (en) 2006-05-11 2014-11-25 Spectrum Dynamics Llc Radiopharmaceuticals for diagnosis and therapy
US8315810B2 (en) * 2006-11-10 2012-11-20 Koninklijke Philips Electronics N.V. Apparatus, method, computer-readable medium, and use for therapy planning in treatment of a patient
US9387344B2 (en) 2006-11-21 2016-07-12 The Johns Hopkins University Methods for determining absorbed dose information
US9275451B2 (en) 2006-12-20 2016-03-01 Biosensors International Group, Ltd. Method, a system, and an apparatus for using and processing multidimensional data
US8260559B2 (en) * 2007-07-20 2012-09-04 General Electric Company System and method for measurement of radioactivity concentration of a radiopharmaceutical
US8521253B2 (en) 2007-10-29 2013-08-27 Spectrum Dynamics Llc Prostate imaging
GB0818490D0 (en) * 2008-10-09 2008-11-12 Siemens Medical Solutions Post injection interval time correction of SUV in static PET scans
WO2010068744A2 (en) * 2008-12-11 2010-06-17 Mount Sinai School Of Medicine Of New York University System and method for generating hybrid bed contour maps
US8688618B2 (en) 2009-06-23 2014-04-01 The Johns Hopkins University Method and system for determining treatment plans
US8693629B2 (en) 2009-12-09 2014-04-08 The Johns Hopkins University Method and system for administering internal radionuclide therapy (IRT) and external radiation therapy (XRT)
US9757084B2 (en) 2011-12-22 2017-09-12 The Johns Hopkins University Method and system for administering radiopharmaceutical therapy (RPT)
US8914237B2 (en) * 2010-01-20 2014-12-16 The John Hopkins University Method and system for gamma camera count rate saturation correction
US8338788B2 (en) 2009-07-29 2012-12-25 Spectrum Dynamics Llc Method and system of optimized volumetric imaging
US10007961B2 (en) * 2009-09-09 2018-06-26 Wisconsin Alumni Research Foundation Treatment planning system for radiopharmaceuticals
US20160066891A1 (en) * 2014-09-10 2016-03-10 International Business Machines Corporation Image representation set
CN104383639B (zh) * 2014-11-28 2017-04-12 四川大学 一种利用模拟分子动力学方法确定后装源驻留时间的方法
FR3050028B1 (fr) 2016-04-08 2020-02-14 Theradial Dispositif de recueil d'un echantillon de dialysat.
JP7389758B2 (ja) 2018-05-18 2023-11-30 バード・ペリフェラル・バスキュラー・インコーポレーテッド 放射線塞栓術処置計画のため線量測定および球体選択をカスタマイズするための線量測定アプリケーションソフトウェアツールの使用のためのシステムおよび方法
CN111951925B (zh) * 2019-05-17 2024-01-30 南京巨鲨显示科技有限公司 一种确定放射性药物注射剂量的系统及方法
US11524178B2 (en) * 2019-10-09 2022-12-13 Siemens Medical Solutions Usa, Inc. Internal dose tomography
WO2022251450A1 (en) * 2021-05-27 2022-12-01 Memorial Sloan-Kettering Cancer Center Lesional dosimetry for targeted radiotherapy of cancer cross-reference to related applications

Family Cites Families (3)

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US4831122A (en) * 1986-01-09 1989-05-16 Regents Of The University Of Minnesota Radioimmunotoxins
US6022521A (en) * 1995-05-04 2000-02-08 The Regents Of The University Of Michigan Method of establishing the optimal radiation dose for radiopharmaceutical treatment of disease
WO1997042522A1 (en) * 1996-05-07 1997-11-13 The Regents Of The University Of California Radiation therapy dose calculation engine

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2722568C1 (ru) * 2019-12-31 2020-06-01 Федеральное Государственное Бюджетное Учреждение "Национальный Медицинский Исследовательский Центр Эндокринологии" Министерства Здравоохранения Российской Федерации (Фгбу "Нмиц Эндокринологии" Минздрава России) Способ определения индивидуальной активности 131-йода для проведения радиойодтерапии тиреотоксикоза и прогнозирования времени достижения безопасного уровня активности 131-йода в организме пациента после введения индивидуальной активности 131-йода

Also Published As

Publication number Publication date
WO1999062565A2 (en) 1999-12-09
EP1083938B1 (de) 2004-11-03
IL140028A0 (en) 2002-02-10
IL140028A (en) 2007-06-03
DE69921650T2 (de) 2005-10-20
US7668662B2 (en) 2010-02-23
AU4333699A (en) 1999-12-20
CA2331064A1 (en) 1999-12-09
AU766107B2 (en) 2003-10-09
EP1083938A2 (de) 2001-03-21
US20050288869A1 (en) 2005-12-29
ES2233083T3 (es) 2005-06-01
WO1999062565A3 (en) 2000-04-06
NZ508674A (en) 2003-09-26
JP2002516884A (ja) 2002-06-11
HK1033553A1 (en) 2001-09-07
ATE281184T1 (de) 2004-11-15
JP5099944B2 (ja) 2012-12-19
EP1523995A3 (de) 2005-04-27
JP2007026431A (ja) 2007-02-01
EP1523995A2 (de) 2005-04-20

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: THE REGENTS OF THE UNIVERSITY OF MICHIGAN, ANN ARB

Owner name: SMITHKLINE BEECHAM CORPORATION, PHILADELPHIA, PA.,