DE69920943D1 - Verfahren zur herstellung von optisch aktiven 3-hydroxy-pyrrolidinderivaten durch enzymatische hydroxylierung - Google Patents
Verfahren zur herstellung von optisch aktiven 3-hydroxy-pyrrolidinderivaten durch enzymatische hydroxylierungInfo
- Publication number
- DE69920943D1 DE69920943D1 DE69920943T DE69920943T DE69920943D1 DE 69920943 D1 DE69920943 D1 DE 69920943D1 DE 69920943 T DE69920943 T DE 69920943T DE 69920943 T DE69920943 T DE 69920943T DE 69920943 D1 DE69920943 D1 DE 69920943D1
- Authority
- DE
- Germany
- Prior art keywords
- optically active
- hydroxy
- producing optically
- pyrrolidine derivatives
- biocatalyst
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/10—Nitrogen as only ring hetero atom
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98203893A EP1002871A1 (de) | 1998-11-17 | 1998-11-17 | Verfahren zur Herstellung von optisch aktiven 3-hydroxy-pyrrolidinderivaten durch enzymatische Hydroxylierung |
| EP98203893 | 1998-11-17 | ||
| PCT/EP1999/009041 WO2000029606A1 (en) | 1998-11-17 | 1999-11-15 | Process for preparing optically active-3-hydroxy-pyrrolidine derivatives by enzymatic hydroxylation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69920943D1 true DE69920943D1 (de) | 2004-11-11 |
| DE69920943T2 DE69920943T2 (de) | 2005-10-13 |
Family
ID=8234352
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69920943T Expired - Fee Related DE69920943T2 (de) | 1998-11-17 | 1999-11-15 | Verfahren zur herstellung von optisch aktiven 3-hydroxy-pyrrolidinderivaten durch enzymatische hydroxylierung |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20020106763A1 (de) |
| EP (2) | EP1002871A1 (de) |
| AT (1) | ATE278798T1 (de) |
| AU (1) | AU1273000A (de) |
| DE (1) | DE69920943T2 (de) |
| WO (1) | WO2000029606A1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1130109A1 (de) | 2000-02-29 | 2001-09-05 | Pfizer Products Inc. | Mikrobiologisches Verfahren zur Herstellung von optisch aktiven 3-Hydroxypyrrolidinderivaten |
| EP1188837A1 (de) * | 2000-09-18 | 2002-03-20 | Eidgenössische Technische Hochschule Zürich | Verfahren zur Herstellung von N-substituierten 4-Hydroxypiperidinen durch enzymatische Hydroxylierung |
| EP1197561A1 (de) * | 2000-10-13 | 2002-04-17 | Eidgenössische Technische Hochschule Zürich | Verfahren zur Herstellung optisch aktiver 4-Hydroxy-2-pyrrolidinone und N-substituierten 4-Hydroxy-2-pyrrolidinonen durch enzymatische hydroxylierung |
| FR2862647B1 (fr) | 2003-11-25 | 2008-07-04 | Aventis Pharma Sa | Derives de pyrazolyle, procede de preparation et intermediaires de ce procede a titre de medicaments et de compositions pharmaceutiques les renfermant |
| EP1926709A4 (de) * | 2005-08-25 | 2009-06-24 | Rstech Corp | Verfahren zur herstellung einer chiralen 3-hydroxypyrrolidinverbindung und derivaten davon mit hoher optischer reinheit |
| US8445700B2 (en) | 2008-11-24 | 2013-05-21 | Council Of Scientific & Industrial Research | Process for the preparation of optically active N-benzyl-3 hydroxypyrrolidines |
| CN113801821B (zh) * | 2021-09-29 | 2023-09-05 | 浙江工业大学 | 新奥尔良分枝杆菌wcj及其在降解有机污染物中的应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1140055A (en) * | 1965-05-04 | 1969-01-15 | Upjohn Co | Improvements in or relating to heterocyclic compounds and the manufacture thereof |
| JP3703928B2 (ja) * | 1996-11-26 | 2005-10-05 | 株式会社カネカ | 光学活性ｎ−ベンジル−３−ピロリジノールの製造方法 |
-
1998
- 1998-11-17 EP EP98203893A patent/EP1002871A1/de not_active Withdrawn
-
1999
- 1999-11-05 US US09/434,906 patent/US20020106763A1/en not_active Abandoned
- 1999-11-15 EP EP99956030A patent/EP1131460B1/de not_active Expired - Lifetime
- 1999-11-15 WO PCT/EP1999/009041 patent/WO2000029606A1/en active IP Right Grant
- 1999-11-15 AT AT99956030T patent/ATE278798T1/de not_active IP Right Cessation
- 1999-11-15 AU AU12730/00A patent/AU1273000A/en not_active Abandoned
- 1999-11-15 DE DE69920943T patent/DE69920943T2/de not_active Expired - Fee Related
-
2003
- 2003-02-24 US US10/372,483 patent/US7141412B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1131460B1 (de) | 2004-10-06 |
| US7141412B2 (en) | 2006-11-28 |
| ATE278798T1 (de) | 2004-10-15 |
| EP1131460A1 (de) | 2001-09-12 |
| DE69920943T2 (de) | 2005-10-13 |
| WO2000029606A1 (en) | 2000-05-25 |
| US20030219883A1 (en) | 2003-11-27 |
| AU1273000A (en) | 2000-06-05 |
| EP1002871A1 (de) | 2000-05-24 |
| US20020106763A1 (en) | 2002-08-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |