ATE278798T1 - Verfahren zur herstellung von optisch aktiven 3- hydroxy-pyrrolidinderivaten durch enzymatische hydroxylierung - Google Patents

Verfahren zur herstellung von optisch aktiven 3- hydroxy-pyrrolidinderivaten durch enzymatische hydroxylierung

Info

Publication number
ATE278798T1
ATE278798T1 AT99956030T AT99956030T ATE278798T1 AT E278798 T1 ATE278798 T1 AT E278798T1 AT 99956030 T AT99956030 T AT 99956030T AT 99956030 T AT99956030 T AT 99956030T AT E278798 T1 ATE278798 T1 AT E278798T1
Authority
AT
Austria
Prior art keywords
optically active
hydroxy
producing optically
pyrrolidine derivatives
biocatalyst
Prior art date
Application number
AT99956030T
Other languages
English (en)
Inventor
Bernard Witholt
Zhi Li
Original Assignee
Eidgenoess Tech Hochschule
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eidgenoess Tech Hochschule filed Critical Eidgenoess Tech Hochschule
Application granted granted Critical
Publication of ATE278798T1 publication Critical patent/ATE278798T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pyrrole Compounds (AREA)
AT99956030T 1998-11-17 1999-11-15 Verfahren zur herstellung von optisch aktiven 3- hydroxy-pyrrolidinderivaten durch enzymatische hydroxylierung ATE278798T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98203893A EP1002871A1 (de) 1998-11-17 1998-11-17 Verfahren zur Herstellung von optisch aktiven 3-hydroxy-pyrrolidinderivaten durch enzymatische Hydroxylierung
PCT/EP1999/009041 WO2000029606A1 (en) 1998-11-17 1999-11-15 Process for preparing optically active-3-hydroxy-pyrrolidine derivatives by enzymatic hydroxylation

Publications (1)

Publication Number Publication Date
ATE278798T1 true ATE278798T1 (de) 2004-10-15

Family

ID=8234352

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99956030T ATE278798T1 (de) 1998-11-17 1999-11-15 Verfahren zur herstellung von optisch aktiven 3- hydroxy-pyrrolidinderivaten durch enzymatische hydroxylierung

Country Status (6)

Country Link
US (2) US20020106763A1 (de)
EP (2) EP1002871A1 (de)
AT (1) ATE278798T1 (de)
AU (1) AU1273000A (de)
DE (1) DE69920943T2 (de)
WO (1) WO2000029606A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1130109A1 (de) * 2000-02-29 2001-09-05 Pfizer Products Inc. Mikrobiologisches Verfahren zur Herstellung von optisch aktiven 3-Hydroxypyrrolidinderivaten
EP1188837A1 (de) * 2000-09-18 2002-03-20 Eidgenössische Technische Hochschule Zürich Verfahren zur Herstellung von N-substituierten 4-Hydroxypiperidinen durch enzymatische Hydroxylierung
EP1197561A1 (de) * 2000-10-13 2002-04-17 Eidgenössische Technische Hochschule Zürich Verfahren zur Herstellung optisch aktiver 4-Hydroxy-2-pyrrolidinone und N-substituierten 4-Hydroxy-2-pyrrolidinonen durch enzymatische hydroxylierung
FR2862647B1 (fr) 2003-11-25 2008-07-04 Aventis Pharma Sa Derives de pyrazolyle, procede de preparation et intermediaires de ce procede a titre de medicaments et de compositions pharmaceutiques les renfermant
EP1926709A4 (de) * 2005-08-25 2009-06-24 Rstech Corp Verfahren zur herstellung einer chiralen 3-hydroxypyrrolidinverbindung und derivaten davon mit hoher optischer reinheit
AU2009318789B2 (en) 2008-11-24 2014-05-29 Council Of Scientific & Industrial Research A Process For The Preparation Of Optically Active N-Benzyl-3-Hydroxypyrrolidines
CN113801821B (zh) * 2021-09-29 2023-09-05 浙江工业大学 新奥尔良分枝杆菌wcj及其在降解有机污染物中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1140055A (en) * 1965-05-04 1969-01-15 Upjohn Co Improvements in or relating to heterocyclic compounds and the manufacture thereof
JP3703928B2 (ja) * 1996-11-26 2005-10-05 株式会社カネカ 光学活性ｎ−ベンジル−３−ピロリジノールの製造方法

Also Published As

Publication number Publication date
WO2000029606A1 (en) 2000-05-25
DE69920943T2 (de) 2005-10-13
DE69920943D1 (de) 2004-11-11
EP1131460B1 (de) 2004-10-06
US20030219883A1 (en) 2003-11-27
EP1131460A1 (de) 2001-09-12
AU1273000A (en) 2000-06-05
US7141412B2 (en) 2006-11-28
EP1002871A1 (de) 2000-05-24
US20020106763A1 (en) 2002-08-08

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Legal Events

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