DE69914940D1 - Diagnostische methode basierend auf der function eines proteins das in einer zellfreien umgebung produziert wird, ausgehend von einer probe von nukleinsäuren - Google Patents

Diagnostische methode basierend auf der function eines proteins das in einer zellfreien umgebung produziert wird, ausgehend von einer probe von nukleinsäuren

Info

Publication number
DE69914940D1
DE69914940D1 DE69914940T DE69914940T DE69914940D1 DE 69914940 D1 DE69914940 D1 DE 69914940D1 DE 69914940 T DE69914940 T DE 69914940T DE 69914940 T DE69914940 T DE 69914940T DE 69914940 D1 DE69914940 D1 DE 69914940D1
Authority
DE
Germany
Prior art keywords
function
nucleic acids
sample
cell
diagnostic method
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69914940T
Other languages
English (en)
Other versions
DE69914940T2 (de
Inventor
Jean-Francois Bloch
Daniel Dupret
Jean-Michel Masson
Fabrice Lefevre
Sandrine Dautel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Proteus SA
Original Assignee
Proteus SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Proteus SA filed Critical Proteus SA
Application granted granted Critical
Publication of DE69914940D1 publication Critical patent/DE69914940D1/de
Publication of DE69914940T2 publication Critical patent/DE69914940T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE69914940T 1998-12-08 1999-12-08 Diagnostische Methode basierend auf der Funktion eines Proteins, das in einer Zellfreien Umgebung produziert wird, ausgehend von einer Probe von Nucleinsäuren Expired - Lifetime DE69914940T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9815487A FR2786787B1 (fr) 1998-12-08 1998-12-08 Methode d'analyse in vitro d'un phenotype connu a partir d'un echantillon d'acides nucleiques
FR9815487 1998-12-08
PCT/FR1999/003059 WO2000034512A1 (fr) 1998-12-08 1999-12-08 Methode de detection et/ou de quantification d'une fonction connue a partir d'un echantillon d'acides nucleiques

Publications (2)

Publication Number Publication Date
DE69914940D1 true DE69914940D1 (de) 2004-03-25
DE69914940T2 DE69914940T2 (de) 2004-12-16

Family

ID=9533724

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69914940T Expired - Lifetime DE69914940T2 (de) 1998-12-08 1999-12-08 Diagnostische Methode basierend auf der Funktion eines Proteins, das in einer Zellfreien Umgebung produziert wird, ausgehend von einer Probe von Nucleinsäuren

Country Status (11)

Country Link
US (1) US8017318B1 (de)
EP (2) EP1431401A3 (de)
JP (1) JP2002531142A (de)
AT (1) ATE259883T1 (de)
AU (1) AU774181B2 (de)
CA (1) CA2354607C (de)
DE (1) DE69914940T2 (de)
ES (1) ES2216592T3 (de)
FR (1) FR2786787B1 (de)
IL (2) IL143638A0 (de)
WO (1) WO2000034512A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2805280B1 (fr) * 2000-02-17 2005-01-14 Proteus Methode de detection d'une inteine specifique de mycobacterium tuberculosis et son utilisation pour le diagnostic de la tuberculose
EP1402064A4 (de) * 2001-05-30 2005-08-24 Gene Therapy Systems Inc Protein-arrays sowie verfahren und systeme für deren herstellung
AU2020329166A1 (en) 2019-08-09 2022-03-03 Nutcracker Therapeutics, Inc. Microfluidic apparatus and methods of use thereof

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4557862A (en) * 1983-10-28 1985-12-10 University Patents, Inc. Rhodamine derivatives as fluorogenic substrates for proteinases
WO1992007949A1 (en) * 1990-11-05 1992-05-14 The United States Of America, As Represented By The Secretary Of The Army Method for the in vitro production of protein from a dna sequence without cloning
US5235039A (en) * 1991-06-10 1993-08-10 Eli Lilly And Company Substrates for hiv protease
JPH07184648A (ja) * 1992-02-07 1995-07-25 Kunitada Shimotoono Ｈｃｖプロテイナーゼ活性物質、その製造法並びに同プロテイナーゼおよび同プロテイナーゼ阻害剤のアッセイ法
WO1994005812A1 (en) * 1992-09-02 1994-03-17 The Scripps Research Institute Coupled isothermal polynucleotide amplification and translation system
US5436131A (en) * 1993-04-02 1995-07-25 Merck & Co., Inc. Color screening assay for identifying inhibitor resistant HIV protease mutants
NZ265504A (en) * 1993-04-08 1996-09-25 Res Dev Foundation Cell free engineering and synthesis of protein, using transcription/translation media
GB9320562D0 (en) * 1993-10-06 1993-11-24 Zeneca Ltd Novel assay and applications
US5709998A (en) * 1993-12-15 1998-01-20 The Johns Hopkins University Molecular diagnosis of familial adenomatous polyposis
US6063562A (en) * 1994-09-16 2000-05-16 Sepracor, Inc. In vitro method for predicting the evolutionary response of HIV protease to a drug targeted thereagainst
KR20000011069A (ko) * 1996-05-09 2000-02-25 스리-디멘셔널 파마슈티컬스 인코포레이티드 리간드 개발 및 다변수 단백질 화학의 최적화를 위한미량이식판 열 이동 분석 및 그 장치
US6207371B1 (en) * 1996-10-04 2001-03-27 Lexicon Genetics Incorporated Indexed library of cells containing genomic modifications and methods of making and utilizing the same
JP4663824B2 (ja) * 1996-12-31 2011-04-06 ハイ スループット ジェノミクス インコーポレイテッド 多重化分子分析装置および方法
EP1003853B1 (de) * 1997-09-03 2005-11-30 Biovation Limited Methoden zur durchforstung (screenen) von proteinen
DE60027472T2 (de) * 1999-12-20 2006-12-07 Et Agroalimentaire Canada, Lennoxville Methode und zusammensetzung zur behandlung und/oder prophylaxe von antibiotikum-resistenten-mikroorganismus infektionen

Also Published As

Publication number Publication date
IL143638A0 (en) 2002-04-21
IL143638A (en) 2007-10-31
FR2786787A1 (fr) 2000-06-09
EP1431401A2 (de) 2004-06-23
AU774181B2 (en) 2004-06-17
CA2354607A1 (fr) 2000-06-15
CA2354607C (fr) 2011-08-09
JP2002531142A (ja) 2002-09-24
US8017318B1 (en) 2011-09-13
EP1137801A1 (de) 2001-10-04
DE69914940T2 (de) 2004-12-16
AU1509900A (en) 2000-06-26
EP1431401A3 (de) 2007-07-25
ATE259883T1 (de) 2004-03-15
EP1137801B1 (de) 2004-02-18
ES2216592T3 (es) 2004-10-16
FR2786787B1 (fr) 2002-04-19
WO2000034512A1 (fr) 2000-06-15
EP1137801B9 (de) 2004-10-06

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