DE69905604D1 - Enantioselective alkylierung von trizyklischen verbindungen - Google Patents

Enantioselective alkylierung von trizyklischen verbindungen

Info

Publication number
DE69905604D1
DE69905604D1 DE69905604T DE69905604T DE69905604D1 DE 69905604 D1 DE69905604 D1 DE 69905604D1 DE 69905604 T DE69905604 T DE 69905604T DE 69905604 T DE69905604 T DE 69905604T DE 69905604 D1 DE69905604 D1 DE 69905604D1
Authority
DE
Germany
Prior art keywords
tricyclic compounds
enantioselective alkylation
enantioselective
alkylation
tricyclic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69905604T
Other languages
English (en)
Other versions
DE69905604T2 (de
Inventor
Shen-Chun Kuo
F Bernard
Xing Chen
Donald Hou
S Kim-Meade
G Wu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme Corp
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of DE69905604D1 publication Critical patent/DE69905604D1/de
Publication of DE69905604T2 publication Critical patent/DE69905604T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DE69905604T 1998-11-20 1999-11-18 Enantioselective alkylierung von trizyklischen verbindungen Expired - Lifetime DE69905604T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19700598A 1998-11-20 1998-11-20
PCT/US1999/026009 WO2000031064A1 (en) 1998-11-20 1999-11-18 Enantioselective alkylation of tricyclic compounds

Publications (2)

Publication Number Publication Date
DE69905604D1 true DE69905604D1 (de) 2003-04-03
DE69905604T2 DE69905604T2 (de) 2003-12-04

Family

ID=22727630

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69905604T Expired - Lifetime DE69905604T2 (de) 1998-11-20 1999-11-18 Enantioselective alkylierung von trizyklischen verbindungen

Country Status (14)

Country Link
EP (1) EP1131313B1 (de)
JP (2) JP4527288B2 (de)
CN (2) CN101544604B (de)
AR (1) AR028139A1 (de)
AT (1) ATE233257T1 (de)
AU (1) AU1606500A (de)
CA (1) CA2352204C (de)
DE (1) DE69905604T2 (de)
DK (1) DK1131313T3 (de)
ES (1) ES2189523T3 (de)
HK (1) HK1038748B (de)
PT (1) PT1131313E (de)
WO (1) WO2000031064A1 (de)
ZA (1) ZA200103243B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE461921T1 (de) * 2002-10-03 2010-04-15 Schering Corp Enantioselektive alkylierung von trizyklischen verbindungen

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03133958A (ja) * 1989-10-18 1991-06-07 Nippon Arukiru Alum Kk 光学活性ピリジルカルビノールの製造方法
JP2879456B2 (ja) * 1989-12-15 1999-04-05 関東化学株式会社 光学活性フルオロアルコールおよびその製造方法
JPH05986A (ja) * 1991-06-20 1993-01-08 Nippon Alkyl Alum Kk 光学活性アルコキシアルコールの製造方法
US5264577A (en) * 1992-04-22 1993-11-23 Warner-Lambert Company Cyclic amino acids and derivatives thereof
US5977125A (en) * 1994-10-31 1999-11-02 Eisai Co., Ltd. Mono-or polyenic carboxylic acid derivatives
US5712280A (en) * 1995-04-07 1998-01-27 Schering Corporation Tricyclic compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
DK1019392T3 (da) * 1995-12-22 2006-03-20 Schering Corp Tricykliske amider anvendelige til inhibering af G-proteinfunktion og til behandling af proliferative sygdomme

Also Published As

Publication number Publication date
HK1038748B (zh) 2003-06-06
HK1038748A1 (en) 2002-03-28
CN101544604B (zh) 2010-09-01
EP1131313A1 (de) 2001-09-12
PT1131313E (pt) 2003-06-30
DE69905604T2 (de) 2003-12-04
AR028139A1 (es) 2003-04-30
CA2352204A1 (en) 2000-06-02
ZA200103243B (en) 2002-07-22
WO2000031064A1 (en) 2000-06-02
EP1131313B1 (de) 2003-02-26
CN100503597C (zh) 2009-06-24
ES2189523T3 (es) 2003-07-01
JP2010189436A (ja) 2010-09-02
DK1131313T3 (da) 2003-03-31
CN1326454A (zh) 2001-12-12
ATE233257T1 (de) 2003-03-15
CN101544604A (zh) 2009-09-30
AU1606500A (en) 2000-06-13
JP4527288B2 (ja) 2010-08-18
CA2352204C (en) 2007-10-16
JP2002530398A (ja) 2002-09-17

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition