DE69841809D1 - Befestigung von substanzen an mikroorganismen - Google Patents

Befestigung von substanzen an mikroorganismen

Info

Publication number
DE69841809D1
DE69841809D1 DE69841809T DE69841809T DE69841809D1 DE 69841809 D1 DE69841809 D1 DE 69841809D1 DE 69841809 T DE69841809 T DE 69841809T DE 69841809 T DE69841809 T DE 69841809T DE 69841809 D1 DE69841809 D1 DE 69841809D1
Authority
DE
Germany
Prior art keywords
attaching
microorganisms
micro
proteinaceous substance
proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69841809T
Other languages
English (en)
Inventor
Girbe Buist
Cornelis Johannes Leenhouts
Gerard Venema
Jan Kok
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Applied Nanosystems BV
Original Assignee
Applied Nanosystems BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Nanosystems BV filed Critical Applied Nanosystems BV
Application granted granted Critical
Publication of DE69841809D1 publication Critical patent/DE69841809D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411—Amylases
    • C12N9/2414—Alpha-amylase (3.2.1.1.)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2462—Lysozyme (3.2.1.17)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/86—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in cyclic amides, e.g. penicillinase (3.5.2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mycology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Dairy Products (AREA)
  • General Preparation And Processing Of Foods (AREA)
DE69841809T 1997-11-13 1998-11-12 Befestigung von substanzen an mikroorganismen Expired - Lifetime DE69841809D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97203539A EP0916726A1 (de) 1997-11-13 1997-11-13 Befestigungs-Substanzen an Mikroorganismen
PCT/NL1998/000655 WO1999025836A1 (en) 1997-11-13 1998-11-12 Attaching substances to micro-organisms

Publications (1)

Publication Number Publication Date
DE69841809D1 true DE69841809D1 (de) 2010-09-16

Family

ID=8228921

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69841809T Expired - Lifetime DE69841809D1 (de) 1997-11-13 1998-11-12 Befestigung von substanzen an mikroorganismen

Country Status (10)

Country Link
US (3) US7169383B1 (de)
EP (2) EP0916726A1 (de)
JP (1) JP5442918B2 (de)
AT (1) ATE476509T1 (de)
AU (1) AU752666B2 (de)
CA (1) CA2310228C (de)
DE (1) DE69841809D1 (de)
DK (1) DK1032675T3 (de)
NZ (1) NZ504486A (de)
WO (1) WO1999025836A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6696251B1 (en) * 1996-05-31 2004-02-24 Board Of Trustees Of The University Of Illinois Yeast cell surface display of proteins and uses thereof
US6759243B2 (en) * 1998-01-20 2004-07-06 Board Of Trustees Of The University Of Illinois High affinity TCR proteins and methods
ES2316458T3 (es) * 2000-07-06 2009-04-16 Id Biomedical Corporation Antigeno de streptococcus pyogenes.
GB0022742D0 (en) * 2000-09-15 2000-11-01 Smithkline Beecham Biolog Vaccine
AU2002254134B2 (en) 2001-03-07 2006-06-01 Children's Medical Center Corporation Method to screen peptide display libraries using minicell display
CA2450318C (en) * 2001-06-11 2011-08-02 Applied Nanosystems B.V. Improved methods for binding acma-type protein anchor fusions to cell-wall material of micro-organisms
JP4204471B2 (ja) * 2001-10-22 2009-01-07 第一三共株式会社 細胞壁作用性薬剤のスクリーニング方法
AU2003225432A1 (en) * 2002-04-04 2003-10-20 Applied Nanosystems B.V. Delivery of a substance to a pre-determined site
EP1350507A1 (de) * 2002-04-04 2003-10-08 Applied NanoSystems B.V. Verabreichung einer Substanz in einen vorbestimmten Zielort
JP2008523116A (ja) 2004-12-14 2008-07-03 アルカベロ アクチェセルスカプ 異種タンパク質化合物をディスプレイするバクテリア細胞を含んでなる医薬組成物
EP1746103A1 (de) 2005-07-20 2007-01-24 Applied NanoSystems B.V. Bifunktionelle Protein-Anker
JP4982849B2 (ja) * 2005-09-29 2012-07-25 国立大学法人広島大学 細菌検出およびグラム陽性／陰性識別方法
US9585953B2 (en) 2011-03-22 2017-03-07 Mucosis B.V. Immunogenic compositions in particulate form and methods for producing the same
RU2476591C1 (ru) * 2011-08-19 2013-02-27 Федеральное государственное образовательное учреждение высшего профессионального образования "Горский государственный аграрный университет" Штамм enterococcus hirae, используемый для приготовления кисломолочных продуктов
RU2477313C1 (ru) * 2011-08-25 2013-03-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Горский государственный аграрный университет" ШТАММ Enterococcus hirae, ИСПОЛЬЗУЕМЫЙ ПРИ ПРОИЗВОДСТВЕ КИСЛОМОЛОЧНЫХ ПРОДУКТОВ
RU2476592C1 (ru) * 2011-09-02 2013-02-27 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Горский государственный аграрный университет" Штамм enterococcus hirae, используемый для производства кисломолочных продуктов
US9060975B2 (en) 2013-03-14 2015-06-23 Mucosis Bv Heat-stable respiratory syncytial virus F protein oligomers and their use in immunological compositions

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5616686A (en) * 1990-05-11 1997-04-01 The Rockefeller University Polypeptide of a hybrid surface protein by bacteria
AU6139794A (en) 1993-02-10 1994-08-29 Unilever Plc Immobilized proteins with specific binding capacities and their use in processes and products
US5510264A (en) * 1993-09-28 1996-04-23 Insight Biotech Inc. Antibodies which bind meningitis related homologous antigenic sequences
AU706127B2 (en) * 1994-05-12 1999-06-10 Quest International B.V. Process for the lysis of a culture of lactic acid bacteria by means of a lysin, and uses of the resulting lysed culture
WO1997008553A1 (en) 1995-08-22 1997-03-06 The Regents Of The University Of California Targeting of proteins to the cell wall of gram-positive bacteria
GB9518323D0 (en) * 1995-09-07 1995-11-08 Steidler Lothar Materials and methods relating to the attachment and display of substances on cell surfaces

Also Published As

Publication number Publication date
WO1999025836A1 (en) 1999-05-27
JP5442918B2 (ja) 2014-03-19
NZ504486A (en) 2003-02-28
EP1032675A1 (de) 2000-09-06
ATE476509T1 (de) 2010-08-15
US20050169937A1 (en) 2005-08-04
US7312311B2 (en) 2007-12-25
DK1032675T3 (da) 2010-11-01
AU1179999A (en) 1999-06-07
US20070104724A1 (en) 2007-05-10
CA2310228A1 (en) 1999-05-27
CA2310228C (en) 2014-05-27
EP0916726A1 (de) 1999-05-19
AU752666B2 (en) 2002-09-26
US7169383B1 (en) 2007-01-30
JP2002514381A (ja) 2002-05-21
EP1032675B1 (de) 2010-08-04

Similar Documents

Publication Publication Date Title
DE69841809D1 (de) Befestigung von substanzen an mikroorganismen
ID20467A (id) Mikroorganisme dan proses-proses untuk pembuatan fermentasi l-sistein, l-sistin, n-asetilserin atau turunan-turunan tiazolidina
BR0008772B1 (pt) vetor de expressão, célula bacteriana ou fúngica cultivada, processos para expandir in vitro células hematopoiéticas e progenitores de células hematopoiéticas, e para detectar a presença de rna de ligando zalfa11 e de ligando zalfa 11 in vitro em uma amostra biológica.
WO1998051799A1 (fr) Nouvel inhibiteur de differentiation
ATE109161T1 (de) Hydrophobe bindungsstelle für adhäsionspeptide.
ATE414162T1 (de) Verfahren und materialien zur herstellung von glucosamin
ATE464386T1 (de) Verfahren zur herstellung sekretierter proteine
ATE247167T1 (de) Methode zur kontrollierten herstellung von polypeptiden in bakterien
ATE282705T1 (de) Verbessertes barstar-gen
ATE222065T1 (de) Verbesserte verfahren zur herstellung von nährhydrolysaten
ES2169225T3 (es) Micro-organismo tolerante del estres y procedimiento de produccion de producto de fermentacion.
DE69532646D1 (de) Verfahren zur herstellung extrazellulärer proteine in bakterien
DE69633676D1 (de) Alkaline protease, verfahren zu ihrer herstellung, anwendung derselben und diese herstellende mikroorganismen
Morihara et al. On the specificity of Bacillus subtilis neutral protease in relation to the compound active site
NZ503020A (en) Bacillus gene for secreted beta-glucuronidase
CA2342072A1 (en) Kunitz domain polypeptide zkun6
NZ296562A (en) Recombinant peptides and secretory mehods for their preparation
CA2252616A1 (en) Biocatalysts with amine acylase activity
CA2337088A1 (en) Methods and constructs for protein expression
DE69941789D1 (de) In vivo-verfahren zur herstellung von proteinen, die nicht-konventionelle aminosäuren enthalten
CA2286395A1 (en) Production method of heterologous protein
JPS557015A (en) Proline acylase, its preparation and preparation of l-proline
EA200500905A1 (ru) Получение псевдомицина pseudomonas syringae
DE69923595D1 (de) Herstellung von proteinen
Matsuoka et al. Microbial process for the production of trans-4-hydroxy-L-proline