DE69837349D1 - Monomer- und dimer-arylisochinolinalkaloide und derivate - Google Patents
Monomer- und dimer-arylisochinolinalkaloide und derivateInfo
- Publication number
- DE69837349D1 DE69837349D1 DE69837349T DE69837349T DE69837349D1 DE 69837349 D1 DE69837349 D1 DE 69837349D1 DE 69837349 T DE69837349 T DE 69837349T DE 69837349 T DE69837349 T DE 69837349T DE 69837349 D1 DE69837349 D1 DE 69837349D1
- Authority
- DE
- Germany
- Prior art keywords
- monomeric
- present
- arylisoquinoline
- compounds
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Tropical Medicine & Parasitology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/001,801 US6140339A (en) | 1994-02-14 | 1997-12-31 | Monomeric and dimeric arylisoquinoline alkaloids and derivatives thereof |
PCT/US1998/027407 WO1999033811A1 (en) | 1997-12-31 | 1998-12-23 | Monomeric and dimeric arylisoquinoline alkaloids and derivatives thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
DE69837349D1 true DE69837349D1 (de) | 2007-04-26 |
Family
ID=21697901
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69837349T Expired - Lifetime DE69837349D1 (de) | 1997-12-31 | 1998-12-23 | Monomer- und dimer-arylisochinolinalkaloide und derivate |
Country Status (8)
Country | Link |
---|---|
US (2) | US6140339A (de) |
EP (1) | EP1045837B1 (de) |
AT (1) | ATE356809T1 (de) |
AU (1) | AU751591B2 (de) |
BR (1) | BR9814575A (de) |
CA (1) | CA2313487A1 (de) |
DE (1) | DE69837349D1 (de) |
WO (1) | WO1999033811A1 (de) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6140339A (en) | 1994-02-14 | 2000-10-31 | The United States Of America As Represented By The Department Of Health And Human Services | Monomeric and dimeric arylisoquinoline alkaloids and derivatives thereof |
US8449858B2 (en) * | 2009-06-10 | 2013-05-28 | Carbon Solutions, Inc. | Continuous extraction technique for the purification of carbon nanomaterials |
US8394159B2 (en) * | 2011-01-31 | 2013-03-12 | Honda Motor Co., Ltd. | Vehicle air cleaner housing |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH541609A (de) * | 1970-02-03 | 1973-09-15 | Ciba Geigy Ag | Verfahren zur Herstellung von Bi-isochinolinonen und deren Verwendung als Fluoreszenzfarbstoffe in Kunststoffen |
US4096190A (en) * | 1976-11-26 | 1978-06-20 | Ici Americas Inc. | Oxidative coupling of alkylphenols catalyzed by metal ammonia complexes |
US5001115A (en) * | 1989-05-17 | 1991-03-19 | University Of Florida | Prodrugs of biologically active hydroxyaromatic compounds |
US5025020A (en) * | 1989-09-28 | 1991-06-18 | Cancer Biologics Of America, Inc. | Use of tetrandrine and its derivatives to treat malaria |
WO1992018125A1 (en) * | 1991-04-12 | 1992-10-29 | The United States Of America, As Represented By The Secretary, U.S. Department Of Commerce | Michellamines useful as antiviral agents, composition and method of treatment |
DE4117080A1 (de) * | 1991-05-25 | 1992-11-26 | Basf Ag | Anwendung von dioncophyllinen als fungizide |
EP0695294A1 (de) * | 1993-04-19 | 1996-02-07 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | Michellamine derivate nützlich als antivirale mittel |
US5571919A (en) * | 1994-07-22 | 1996-11-05 | The United States Of America As Represented By The Department Of Health And Human Services | Dimeric naphthylisoquinoline alkaloids and synthesis methods thereof |
US5578729A (en) * | 1994-07-22 | 1996-11-26 | The United States Of America As Represented By The Department Of Health And Human Services | Dimeric arylisoquinoline alkaloid compounds |
US5639761A (en) * | 1994-02-14 | 1997-06-17 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Antimalarial naphthylisoquinoline alkaloids and pharmaceutical compositions and medical uses thereof |
US5552550A (en) * | 1994-07-22 | 1996-09-03 | The United States Of America, As Represented By The Department Of Health And Human Services | Monomeric Naphthylisoquinoline alkaloids and synthesis methods thereof |
US5409938A (en) * | 1994-02-14 | 1995-04-25 | The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Antimalarial korupensamines and pharmaceutical compositions and medical uses thereof |
US6140339A (en) | 1994-02-14 | 2000-10-31 | The United States Of America As Represented By The Department Of Health And Human Services | Monomeric and dimeric arylisoquinoline alkaloids and derivatives thereof |
ES2197205T3 (es) * | 1994-07-22 | 2004-01-01 | The United States Of America, As Represented By The Secretary, Departm. Of Health And Human Services | Alcaloides monomericos y dimericos de naftilisoquinoleina y procedimiento de sintesis de los mismos. |
US5543523A (en) * | 1994-11-15 | 1996-08-06 | Regents Of The University Of Minnesota | Method and intermediates for the synthesis of korupensamines |
-
1997
- 1997-12-31 US US09/001,801 patent/US6140339A/en not_active Expired - Fee Related
-
1998
- 1998-12-23 DE DE69837349T patent/DE69837349D1/de not_active Expired - Lifetime
- 1998-12-23 CA CA002313487A patent/CA2313487A1/en not_active Abandoned
- 1998-12-23 WO PCT/US1998/027407 patent/WO1999033811A1/en active IP Right Grant
- 1998-12-23 EP EP98966748A patent/EP1045837B1/de not_active Expired - Lifetime
- 1998-12-23 AU AU24496/99A patent/AU751591B2/en not_active Ceased
- 1998-12-23 BR BR9814575-4A patent/BR9814575A/pt not_active Application Discontinuation
- 1998-12-23 AT AT98966748T patent/ATE356809T1/de not_active IP Right Cessation
-
2000
- 2000-03-16 US US09/527,002 patent/US6331630B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US6140339A (en) | 2000-10-31 |
ATE356809T1 (de) | 2007-04-15 |
US6331630B1 (en) | 2001-12-18 |
AU2449699A (en) | 1999-07-19 |
BR9814575A (pt) | 2000-10-10 |
EP1045837B1 (de) | 2007-03-14 |
EP1045837A1 (de) | 2000-10-25 |
CA2313487A1 (en) | 1999-07-08 |
AU751591B2 (en) | 2002-08-22 |
WO1999033811A1 (en) | 1999-07-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NZ234327A (en) | Quinazoline derivatives and pharmaceutical compositions | |
CA2134964A1 (en) | Bridged Aza-Bicyclic Derivatives as Substance P Antagonists | |
EA200200716A1 (ru) | Арилконденсированные азаполициклические соединения | |
ATE203515T1 (de) | Meta-substituierte phenylsulphonamidderivate | |
BR9909488A (pt) | Ecteinascidinas semi-sintéticas | |
BRPI0209216B8 (pt) | derivados de quinolina e de quinazolina, composições farmacêuticas compreendendo os mesmos e seus usos | |
ATE242254T1 (de) | Kondensierte 1,2,4-thiadiazinderivate, ihre herstellung und verwendung | |
HUP0401643A2 (hu) | Szubsztituált karbamid neuropeptid Y Y5 receptor antagonisták, alkalmazásuk és ezeket tartalmazó gyógyszerkészítmények | |
LV12047A (lv) | Kondenseti pirimidina atvasinajumi un to lietosana par angiotenzina II antagonistiem | |
ATE377602T1 (de) | Morphinanderivate und ihre medizinische anwendung | |
ES2090081T3 (es) | Derivados de indolocarbazol, procedimientos para su obtencion y su empleo. | |
EA200000996A1 (ru) | Конденсированные с арилом азаполициклические соединения | |
EA200300579A1 (ru) | Соединение лактама | |
EA200101234A1 (ru) | Новые производные аминотиазола, их получение и содержащие их фармацевтические композиции | |
MXPA04006113A (es) | Derivados de triazoloquinolina utiles como ligandos receptores de adenosina. | |
ATE356809T1 (de) | Monomer- und dimer-arylisochinolinalkaloide und derivate | |
ATE416174T1 (de) | Substituierte homopiperidylbenzimidazolanaloga als fundusrelaxantien | |
EA200400323A1 (ru) | Аралкилтетрагидропиридины, их получение и содержащие их фармацевтические композиции | |
MY129094A (en) | Condensed polycyclic compounds | |
TR200001080T2 (tr) | 2 ile ikame edilmiş 1,2-Benisotiyazol türevleri ve bunların serrotonın antagonistleri | |
EA199800368A1 (ru) | Новые промежуточные продукты и их использование для получения n,n'-мостиковых бисиндолилмалеимидов | |
DK1178985T3 (da) | Substituerede thienocycloalk(en)ylamino-1,3,5-triaziner | |
DE69904025D1 (de) | Kondensierte Pyrimidinderivate und diese enthaltende pharmazeutische Zubereitungen | |
FR2397836A1 (fr) | Derives de l'oxo-1-dihydro-1,2-isoquinoleine utilises comme agents anti-inflammatoires analgesiques forts | |
CO5150221A1 (es) | Nuevas 3-fenoxi- y 3-fenilalquiloxi-2-fenil-propilaminas sustituidas |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8332 | No legal effect for de |