DE69829223D1 - Zytotoxische alkaloidderivate, die asmarin a und b umfassen, und aus einem schwamm isoliert wurden - Google Patents

Zytotoxische alkaloidderivate, die asmarin a und b umfassen, und aus einem schwamm isoliert wurden

Info

Publication number
DE69829223D1
DE69829223D1 DE69829223T DE69829223T DE69829223D1 DE 69829223 D1 DE69829223 D1 DE 69829223D1 DE 69829223 T DE69829223 T DE 69829223T DE 69829223 T DE69829223 T DE 69829223T DE 69829223 D1 DE69829223 D1 DE 69829223D1
Authority
DE
Germany
Prior art keywords
isolated
sponge
lower alkyl
asmarin
alkaloid derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69829223T
Other languages
English (en)
Other versions
DE69829223T2 (de
Inventor
Yoel Kashman
Amira Rudi
Tesfamariam Yosief
Dolores G Gravalos
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Instituto Biomar SA
Original Assignee
Instituto Biomar SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Instituto Biomar SA filed Critical Instituto Biomar SA
Publication of DE69829223D1 publication Critical patent/DE69829223D1/de
Application granted granted Critical
Publication of DE69829223T2 publication Critical patent/DE69829223T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/16—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69829223T 1997-12-23 1998-12-23 Zytotoxische alkaloidderivate, die asmarin a und b umfassen, und aus einem schwamm isoliert wurden Expired - Fee Related DE69829223T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9727301.5A GB9727301D0 (en) 1997-12-23 1997-12-23 Asmarine A and B: New cytotoxic alkaloids
GB9727301 1997-12-23
PCT/GB1998/003884 WO1999033832A1 (en) 1997-12-23 1998-12-23 Cytotoxic alkaloid derivatives including asmarine a and b isolated from a sponge

Publications (2)

Publication Number Publication Date
DE69829223D1 true DE69829223D1 (de) 2005-04-07
DE69829223T2 DE69829223T2 (de) 2006-01-12

Family

ID=10824201

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69829223T Expired - Fee Related DE69829223T2 (de) 1997-12-23 1998-12-23 Zytotoxische alkaloidderivate, die asmarin a und b umfassen, und aus einem schwamm isoliert wurden

Country Status (16)

Country Link
EP (1) EP1070067B1 (de)
JP (1) JP2001527076A (de)
KR (1) KR100533244B1 (de)
CN (1) CN1258534C (de)
AT (1) ATE290005T1 (de)
AU (1) AU763093B2 (de)
BR (1) BR9814462A (de)
CA (1) CA2316308A1 (de)
DE (1) DE69829223T2 (de)
ES (1) ES2238782T3 (de)
GB (1) GB9727301D0 (de)
HU (1) HUP0100838A3 (de)
IL (1) IL136956A0 (de)
PL (1) PL341475A1 (de)
RU (1) RU2221800C2 (de)
WO (1) WO1999033832A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JOP20190254A1 (ar) 2017-04-27 2019-10-27 Pharma Mar Sa مركبات مضادة للأورام

Also Published As

Publication number Publication date
HUP0100838A3 (en) 2001-12-28
DE69829223T2 (de) 2006-01-12
KR100533244B1 (ko) 2005-12-05
WO1999033832A1 (en) 1999-07-08
GB9727301D0 (en) 1998-02-25
CN1258534C (zh) 2006-06-07
JP2001527076A (ja) 2001-12-25
AU763093B2 (en) 2003-07-10
HUP0100838A2 (hu) 2001-09-28
ATE290005T1 (de) 2005-03-15
IL136956A0 (en) 2001-06-14
CA2316308A1 (en) 1999-07-08
KR20010033447A (ko) 2001-04-25
AU1774099A (en) 1999-07-19
PL341475A1 (en) 2001-04-23
BR9814462A (pt) 2000-10-10
ES2238782T3 (es) 2005-09-01
EP1070067B1 (de) 2005-03-02
RU2221800C2 (ru) 2004-01-20
CN1336928A (zh) 2002-02-20
EP1070067A1 (de) 2001-01-24

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee