DE69816054D1 - Einmalinhalator - Google Patents

Einmalinhalator

Info

Publication number
DE69816054D1
DE69816054D1 DE69816054T DE69816054T DE69816054D1 DE 69816054 D1 DE69816054 D1 DE 69816054D1 DE 69816054 T DE69816054 T DE 69816054T DE 69816054 T DE69816054 T DE 69816054T DE 69816054 D1 DE69816054 D1 DE 69816054D1
Authority
DE
Germany
Prior art keywords
container
dose
subsidiary
substance
medicament
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69816054T
Other languages
English (en)
Other versions
DE69816054T2 (de
Inventor
Carin Widerstroem
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Application granted granted Critical
Publication of DE69816054D1 publication Critical patent/DE69816054D1/de
Publication of DE69816054T2 publication Critical patent/DE69816054T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001—Particle size control
    • A61M11/002—Particle size control by flow deviation causing inertial separation of transported particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0043—Non-destructive separation of the package, e.g. peeling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0048—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged in a plane, e.g. on diskettes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0066—Inhalators with dosage or measuring devices with means for varying the dose size
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Laser Beam Printer (AREA)
  • Electron Beam Exposure (AREA)
DE69816054T 1997-02-07 1998-01-29 Einmalinhalator Expired - Lifetime DE69816054T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9700423 1997-02-07
SE9700423A SE9700423D0 (sv) 1997-02-07 1997-02-07 Disposable inhaler
PCT/SE1998/000131 WO1998034663A1 (en) 1997-02-07 1998-01-29 Disposable inhaler

Publications (2)

Publication Number Publication Date
DE69816054D1 true DE69816054D1 (de) 2003-08-07
DE69816054T2 DE69816054T2 (de) 2004-04-15

Family

ID=20405705

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69816054T Expired - Lifetime DE69816054T2 (de) 1997-02-07 1998-01-29 Einmalinhalator

Country Status (8)

Country Link
US (1) US7533668B1 (de)
EP (1) EP0973570B1 (de)
AT (1) ATE244032T1 (de)
AU (1) AU6009098A (de)
DE (1) DE69816054T2 (de)
HK (1) HK1025270A1 (de)
SE (1) SE9700423D0 (de)
WO (1) WO1998034663A1 (de)

Families Citing this family (47)

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GB9905538D0 (en) 1999-03-10 1999-05-05 Glaxo Group Ltd A device
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US6679256B2 (en) * 1999-12-17 2004-01-20 Nektar Therapeutics Systems and methods for extracting powders from receptacles
JP2004531333A (ja) * 2001-06-20 2004-10-14 ネクター セラピューティクス 粉末エアロゾル化装置及び方法
US7931022B2 (en) 2001-10-19 2011-04-26 Respirks, Inc. Method and apparatus for dispensing inhalator medicament
ES2300568T3 (es) 2002-03-20 2008-06-16 Mannkind Corporation Aparato de inhalacion.
GR1004350B (el) * 2002-03-29 2003-09-26 Συσκευη εισπνοων ξηρης σκονης
CA2575692C (en) 2004-08-20 2014-10-14 Mannkind Corporation Catalysis of diketopiperazine synthesis
KR20130066695A (ko) 2004-08-23 2013-06-20 맨카인드 코포레이션 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염
US8763605B2 (en) 2005-07-20 2014-07-01 Manta Devices, Llc Inhalation device
CN104324362B (zh) 2005-09-14 2018-04-24 曼金德公司 以提高活性试剂对结晶微粒表面的亲和力为基础的药物配制方法
GB0520794D0 (en) * 2005-10-12 2005-11-23 Innovata Biomed Ltd Inhaler
MX2008010721A (es) 2006-02-22 2008-09-01 Mannkind Corp Un metodo para mejorar las propiedades farmaceuticas de microparticulas que contienen dicetopiperazina y un agente activo.
GR1005668B (el) * 2006-05-09 2007-10-02 Συσκευη εισπνοων ξηρης σκονης για την ταυτοχρονη χορηγηση περισσοτερων απο μιας φαρμακευτικων ουσιων
EP2043717A1 (de) * 2006-07-14 2009-04-08 Astra Zeneca AB Inhaliersystem und abgabevorrichtung zur verabreichung eines arzneimittels in form eines trockenpulvers
EP2230934B8 (de) 2007-12-14 2012-10-24 AeroDesigns, Inc Abgabe von aerosol-sprühbaren nahrungsmittelprodukten
AU2008341217B2 (en) * 2007-12-20 2012-04-12 Astrazeneca Ab Dispenser and method for entraining powder in an airflow 537
US8424518B2 (en) 2008-06-13 2013-04-23 Mannkind Corporation Dry powder inhaler and system for drug delivery
US8485180B2 (en) * 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
EP2609954B1 (de) 2008-06-20 2021-12-29 MannKind Corporation Interaktives Gerät für die Echtzeit-Profilierung von Inhalationsversuchen
TWI494123B (zh) 2008-08-11 2015-08-01 Mannkind Corp 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
JP5667095B2 (ja) 2009-03-11 2015-02-12 マンカインド コーポレイション 吸入器の抵抗を測定するための装置、システムおよび方法
KR20180036807A (ko) 2009-06-12 2018-04-09 맨카인드 코포레이션 한정된 비표면적을 갖는 디케토피페라진 마이크로입자
EP2448623B1 (de) 2009-07-01 2017-12-20 AstraZeneca AB Spender und verfahren zur einspeisung von pulver in einen luftstrom
WO2011056889A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
WO2011071845A1 (en) * 2009-12-08 2011-06-16 Meadwestvaco Calmar Gmbh Powder delivery device and methods of making the same
CA2801936C (en) 2010-06-21 2021-06-01 Mannkind Corporation Dry powder drug delivery system and methods
CN103826988B (zh) 2011-04-01 2016-03-09 曼金德公司 用于药物药盒的泡罩包装
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
WO2013036881A2 (en) * 2011-09-07 2013-03-14 Syphase, Llc Dry powder inhalation device
AU2012328885B2 (en) 2011-10-24 2017-08-31 Mannkind Corporation Methods and compositions for treating pain
JP6199375B2 (ja) 2012-05-09 2017-09-20 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ネブライザ
AU2013289957B2 (en) 2012-07-12 2017-02-23 Mannkind Corporation Dry powder drug delivery systems and methods
WO2014066856A1 (en) 2012-10-26 2014-05-01 Mannkind Corporation Inhalable influenza vaccine compositions and methods
CA2906817C (en) 2013-03-15 2022-01-18 Mannkind Corporation Microcrystalline diketopiperazine compositions and methods
MX2016000739A (es) 2013-07-18 2017-04-06 Mannkind Corp Composiciones farmacéuticas en polvo seco estables al calor y métodos.
CA2920488C (en) 2013-08-05 2022-04-26 Mannkind Corporation Insufflation apparatus and methods
US11491288B2 (en) 2014-01-08 2022-11-08 Seroton, Inc. Dispenser for dry-powder inhalation devices
US10238820B2 (en) 2014-01-08 2019-03-26 Seroton, Inc. Dry-powder inhalation device
WO2015148905A1 (en) 2014-03-28 2015-10-01 Mannkind Corporation Use of ultrarapid acting insulin
US11147936B2 (en) * 2014-05-02 2021-10-19 Manta Devices, Llc Dose delivery device with cover connected to dose chamber seal
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
DE102014017409B4 (de) * 2014-11-26 2016-06-09 Klaus Dieter Beller Einzeldosis-Pulverinhalator und Verfahren zu dessen Herstellung
SE539111C2 (en) * 2015-06-03 2017-04-11 Iconovo Ab Single dose dry powder inhaler
EP3600504B1 (de) 2017-03-28 2023-07-12 Concentrx Pharmaceuticals, Inc. Vorrichtung zur ausgabe von trockenpulvermedikamenten
EA201992119A1 (ru) * 2017-04-06 2020-03-27 Милан Инк. Недорогой ингалятор порошка для одноразового использования

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5239991A (en) * 1989-06-21 1993-08-31 Fisons Plc Disposable powder medicament inhalation device with peel-off cover
SE9002895D0 (sv) * 1990-09-12 1990-09-12 Astra Ab Inhalation devices for dispensing powders i
EP0558879B1 (de) * 1992-03-04 1997-05-14 Astra Aktiebolag Wegwerfinhalator
US5888477A (en) * 1993-01-29 1999-03-30 Aradigm Corporation Use of monomeric insulin as a means for improving the bioavailability of inhaled insulin
US5915378A (en) * 1993-01-29 1999-06-29 Aradigm Corporation Creating an aerosolized formulation of insulin
US5970973A (en) * 1993-01-29 1999-10-26 Aradigm Corporation Method of delivering insulin lispro
US5743250A (en) * 1993-01-29 1998-04-28 Aradigm Corporation Insulin delivery enhanced by coached breathing
US5873358A (en) * 1993-01-29 1999-02-23 Aradigm Corporation Method of maintaining a diabetic patient's blood glucose level in a desired range
US6024090A (en) * 1993-01-29 2000-02-15 Aradigm Corporation Method of treating a diabetic patient by aerosolized administration of insulin lispro
DE4400084C2 (de) * 1994-01-04 2001-08-02 Softec Gmbh & Co Kg Vorrichtung zum Verabreichen von Medikamenten in fester in einem Luftstrom fein verteilter Form
PT101450B (pt) * 1994-02-02 1999-11-30 Hovione Produtos Farmaceuticos Novo dispositivo para inalacao
US5582591A (en) * 1994-09-02 1996-12-10 Delab Delivery of solid drug compositions
DE19523516C1 (de) * 1995-06-30 1996-10-31 Asta Medica Ag Inhalator zum Verabreichen von Medikamenten aus Blisterpackungen
SE9502799D0 (sv) * 1995-08-10 1995-08-10 Astra Ab Device in inhalers
US5797392C1 (en) * 1996-01-22 2001-01-09 Direct Haler As Inhaler
SE9700422D0 (sv) * 1997-02-07 1997-02-07 Astra Ab Single dose inhaler II
US5945123A (en) * 1998-04-02 1999-08-31 K-V Pharmaceutical Company Maximizing effectiveness of substances used to improve health and well being

Also Published As

Publication number Publication date
US7533668B1 (en) 2009-05-19
ATE244032T1 (de) 2003-07-15
EP0973570B1 (de) 2003-07-02
AU6009098A (en) 1998-08-26
DE69816054T2 (de) 2004-04-15
EP0973570A1 (de) 2000-01-26
HK1025270A1 (en) 2000-11-10
SE9700423D0 (sv) 1997-02-07
WO1998034663A1 (en) 1998-08-13

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition