DE69810146D1 - Analgetika, einen cholezystokinin antagonisten und ein opioid enthaltend - Google Patents

Analgetika, einen cholezystokinin antagonisten und ein opioid enthaltend

Info

Publication number
DE69810146D1
DE69810146D1 DE69810146T DE69810146T DE69810146D1 DE 69810146 D1 DE69810146 D1 DE 69810146D1 DE 69810146 T DE69810146 T DE 69810146T DE 69810146 T DE69810146 T DE 69810146T DE 69810146 D1 DE69810146 D1 DE 69810146D1
Authority
DE
Germany
Prior art keywords
opioid
analgetic
cholecystokinin antagonist
antagonist
amount
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69810146T
Other languages
English (en)
Other versions
DE69810146T2 (de
Inventor
Lars Iversen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Panos Therapeutics Ltd
Original Assignee
Panos Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Panos Therapeutics Ltd filed Critical Panos Therapeutics Ltd
Publication of DE69810146D1 publication Critical patent/DE69810146D1/de
Application granted granted Critical
Publication of DE69810146T2 publication Critical patent/DE69810146T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Dispersion Chemistry (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Electrotherapy Devices (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
DE69810146T 1997-10-15 1998-10-12 Analgetika, einen cholezystokinin antagonisten und ein opioid enthaltend Expired - Fee Related DE69810146T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9721746.7A GB9721746D0 (en) 1997-10-15 1997-10-15 Compositions
PCT/GB1998/003076 WO1999018967A1 (en) 1997-10-15 1998-10-12 Analgesic compositions

Publications (2)

Publication Number Publication Date
DE69810146D1 true DE69810146D1 (de) 2003-01-23
DE69810146T2 DE69810146T2 (de) 2003-11-13

Family

ID=10820524

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69810146T Expired - Fee Related DE69810146T2 (de) 1997-10-15 1998-10-12 Analgetika, einen cholezystokinin antagonisten und ein opioid enthaltend

Country Status (8)

Country Link
EP (1) EP1023072B1 (de)
JP (1) JP2001519396A (de)
AT (1) ATE229337T1 (de)
AU (1) AU9547598A (de)
DE (1) DE69810146T2 (de)
ES (1) ES2189252T3 (de)
GB (1) GB9721746D0 (de)
WO (1) WO1999018967A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050192220A1 (en) * 2001-02-05 2005-09-01 Gevys Pharmaceuticas Ltd. Composition and method for potentiating drugs
GB0201367D0 (en) * 2002-01-22 2002-03-13 Ml Lab Plc Composition
US6713470B2 (en) * 2002-01-22 2004-03-30 Ml Laboratories Plc Method of treatment
GB0208129D0 (en) * 2002-04-09 2002-05-22 Ml Lab Plc Method of treatment
GB0207091D0 (en) * 2002-03-26 2002-05-08 Ml Lab Plc Method of treatment
ITRM20020194A1 (it) 2002-04-09 2003-10-09 Sigma Tau Healthscience Spa Composizione utile per aumentare la concentrazione e la motilita' degli spermatozoi e migliorarne la morfologia nell'uomo.
GB0213198D0 (en) * 2002-06-10 2002-07-17 Ml Lab Plc Method of treatment
WO2005007114A2 (en) * 2003-07-14 2005-01-27 Creagri, Inc. Method of treating diabetes type ii
AU2004285327A1 (en) * 2003-10-21 2005-05-12 Arakis Ltd. The use of non-opiates for the potentation of opiates
US20090286832A1 (en) * 2008-05-15 2009-11-19 Kiichiro Nabeta Narcotic emulsion formulations for treatment of surgical pain
FR2934953B1 (fr) * 2008-08-14 2011-01-21 Commissariat Energie Atomique Nanoemulsions de nanocristaux
FR2934955B1 (fr) 2008-08-14 2011-07-08 Commissariat Energie Atomique Encapsulation d'agents therapeutiques lipophiles ou amphiphiles dans des nanoemulsions
FR2934954B1 (fr) 2008-08-14 2011-07-22 Commissariat Energie Atomique Emulsion fluorescente de vert d'indocyanine
GB0818473D0 (en) 2008-10-08 2008-11-12 Probio Nutraceuticals As Composition
CN102333443A (zh) 2009-02-26 2012-01-25 帝国制药美国公司 治疗癌症疼痛的麻醉乳液制剂
GB201006175D0 (en) * 2010-04-14 2010-06-02 Ayanda As Composition
GB201006200D0 (en) * 2010-04-14 2010-06-02 Ayanda As Composition
US9132096B1 (en) 2014-09-12 2015-09-15 Alkermes Pharma Ireland Limited Abuse resistant pharmaceutical compositions

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1564039A (en) * 1976-12-09 1980-04-02 Berger F Analgesic compositions comprising dextropropoxyphene and benzodiazepines
IE57892B1 (en) * 1984-06-25 1993-05-05 Rotta Research Lab Glutamic and aspartic acid derivatives
US4797286A (en) * 1985-11-12 1989-01-10 Eli Lilly And Company Orally administerable sustained release pharmaceutical formulations
AU614465B2 (en) * 1989-04-05 1991-08-29 Yissum Research Development Company Of The Hebrew University Of Jerusalem Medicinal emulsions

Also Published As

Publication number Publication date
EP1023072A1 (de) 2000-08-02
GB9721746D0 (en) 1997-12-10
EP1023072B1 (de) 2002-12-11
WO1999018967A1 (en) 1999-04-22
ATE229337T1 (de) 2002-12-15
AU9547598A (en) 1999-05-03
DE69810146T2 (de) 2003-11-13
JP2001519396A (ja) 2001-10-23
ES2189252T3 (es) 2003-07-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee