DE69740050D1 - Atmosphärendruckionenquelle - Google Patents

Atmosphärendruckionenquelle

Info

Publication number
DE69740050D1
DE69740050D1 DE69740050T DE69740050T DE69740050D1 DE 69740050 D1 DE69740050 D1 DE 69740050D1 DE 69740050 T DE69740050 T DE 69740050T DE 69740050 T DE69740050 T DE 69740050T DE 69740050 D1 DE69740050 D1 DE 69740050D1
Authority
DE
Germany
Prior art keywords
api
capillary
heater
atmospheric pressure
endplate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69740050T
Other languages
English (en)
Inventor
Craig M Whitehouse
Bruce A Andrien
Michael A Sansone
Clement Catalano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Revvity Health Sciences Inc
Original Assignee
PerkinElmer Health Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PerkinElmer Health Sciences Inc filed Critical PerkinElmer Health Sciences Inc
Application granted granted Critical
Publication of DE69740050D1 publication Critical patent/DE69740050D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/02Details
    • H01J49/04Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0468Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components with means for heating or cooling the sample
    • H01J49/0477Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components with means for heating or cooling the sample using a hot fluid
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/02Details
    • H01J49/04Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0404Capillaries used for transferring samples or ions
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/02Details
    • H01J49/04Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0431Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples
    • H01J49/044Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples with means for preventing droplets from entering the analyzer; Desolvation of droplets

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Electron Tubes For Measurement (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69740050T 1996-09-10 1997-09-10 Atmosphärendruckionenquelle Expired - Lifetime DE69740050D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2586696P 1996-09-10 1996-09-10
PCT/US1997/015968 WO1998011595A1 (en) 1996-09-10 1997-09-10 Improvements to atmospheric pressure ion sources

Publications (1)

Publication Number Publication Date
DE69740050D1 true DE69740050D1 (de) 2010-12-23

Family

ID=21828477

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69740050T Expired - Lifetime DE69740050D1 (de) 1996-09-10 1997-09-10 Atmosphärendruckionenquelle

Country Status (7)

Country Link
US (1) US6593568B1 (de)
EP (1) EP0925601B1 (de)
AT (1) ATE488025T1 (de)
AU (1) AU4338997A (de)
CA (1) CA2268448C (de)
DE (1) DE69740050D1 (de)
WO (1) WO1998011595A1 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2328074B (en) 1997-08-06 2001-11-07 Masslab Ltd Ion source for a mass analyser and method of cleaning an ion source
EP0966022B1 (de) 1998-06-18 2007-05-30 Micromass UK Limited Mehrfachprobeninlassmassenspektrometer
JP3876554B2 (ja) * 1998-11-25 2007-01-31 株式会社日立製作所 化学物質のモニタ方法及びモニタ装置並びにそれを用いた燃焼炉
GB2425399B (en) * 2002-05-31 2007-03-14 Waters Investments Ltd A high speed combination multi-mode ionization source for mass spectrometers
US7208727B2 (en) * 2003-01-14 2007-04-24 Georgia Tech Research Corporation Electrospray systems and methods
US7312440B2 (en) * 2003-01-14 2007-12-25 Georgia Tech Research Corporation Integrated micro fuel processor and flow delivery infrastructure
US7427750B2 (en) * 2003-01-17 2008-09-23 Griffin Analytical Technologies, L.L.C. Mass spectrometer assemblies, mass spectrometry vacuum chamber lid assemblies, and mass spectrometer operational methods
US7199364B2 (en) * 2004-05-21 2007-04-03 Thermo Finnigan Llc Electrospray ion source apparatus
WO2006002027A2 (en) * 2004-06-15 2006-01-05 Griffin Analytical Technologies, Inc. Portable mass spectrometer configured to perform multidimensional mass analysis
US7145136B2 (en) * 2004-12-17 2006-12-05 Varian, Inc. Atmospheric pressure ionization with optimized drying gas flow
DE112006001030T5 (de) 2005-04-25 2008-03-20 Griffin Analytical Technologies L.L.C., West Lafayette Analyseinstrumente, -Vorrichtungen und -Verfahren
US7335877B1 (en) * 2005-12-30 2008-02-26 Metara, Inc. Inline automated chemical analysis signal optimization
CN1901137B (zh) * 2006-06-20 2010-05-12 周振 大气压离子源接口及其实现方法与应用
US7992424B1 (en) 2006-09-14 2011-08-09 Griffin Analytical Technologies, L.L.C. Analytical instrumentation and sample analysis methods
US7547891B2 (en) * 2007-02-16 2009-06-16 Agilent Technologies, Inc. Ion sampling apparatuses in fast polarity-switching ion sources
US7564029B2 (en) * 2007-08-15 2009-07-21 Varian, Inc. Sample ionization at above-vacuum pressures
US20100282966A1 (en) * 2008-05-30 2010-11-11 DH Technologies Development Pte Ltd. Method and system for vacuum driven mass spectrometer interface with adjustable resolution and selectivity
WO2009143623A1 (en) * 2008-05-30 2009-12-03 Mds Analytical Technologies Method and system for vacuum driven differential mobility spectrometer/mass spectrometer interface with adjustable resolution and selectivity
US20100154568A1 (en) * 2008-11-19 2010-06-24 Roth Michael J Analytical Instruments, Assemblies, and Methods
US7939798B2 (en) * 2009-01-30 2011-05-10 Agilent Technologies, Inc. Tandem ionizer ion source for mass spectrometer and method of use
CN102347199B (zh) * 2010-08-04 2014-07-02 江苏天瑞仪器股份有限公司 Esi源质谱中金属毛细管伸出长度的微调机构
CN102903596B (zh) * 2012-09-18 2015-08-12 清华大学 一种离子源温控加热装置
WO2015100233A2 (en) * 2013-12-24 2015-07-02 Waters Technologies Corporation Atmospheric interface for electrically grounded electrospray
DE102014113482B4 (de) 2014-09-18 2019-01-03 Bruker Daltonik Gmbh Ionisierungskammer mit temperierter Gaszufuhr
CN106298429B (zh) * 2016-09-20 2018-03-06 中国科学技术大学 一种电喷雾离子源装置
CN110211863B (zh) * 2019-06-14 2021-04-23 清华大学深圳研究生院 一种微量液体样品定量进样装置及方法
WO2023021424A1 (en) * 2021-08-18 2023-02-23 Dh Technologies Development Pte. Ltd. Sealing interface for curtain chamber

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4023398A (en) * 1975-03-03 1977-05-17 John Barry French Apparatus for analyzing trace components
US4542293A (en) * 1983-04-20 1985-09-17 Yale University Process and apparatus for changing the energy of charged particles contained in a gaseous medium
US4531056A (en) * 1983-04-20 1985-07-23 Yale University Method and apparatus for the mass spectrometric analysis of solutions
US4960992A (en) * 1983-08-30 1990-10-02 Research Corporation Technologies Method and means for vaporizing liquids by means of heating a sample capillary tube for detection or analysis
JP2834136B2 (ja) * 1988-04-27 1998-12-09 株式会社日立製作所 質量分析計
JPH0675390B2 (ja) * 1990-11-30 1994-09-21 株式会社島津製作所 質量分析計イオン源装置
US5171990A (en) * 1991-05-17 1992-12-15 Finnigan Corporation Electrospray ion source with reduced neutral noise and method
JP2902197B2 (ja) * 1992-02-04 1999-06-07 株式会社日立製作所 大気圧イオン化質量分析装置
US5304798A (en) * 1992-04-10 1994-04-19 Millipore Corporation Housing for converting an electrospray to an ion stream
US5352892A (en) * 1992-05-29 1994-10-04 Cornell Research Foundation, Inc. Atmospheric pressure ion interface for a mass analyzer
US5349186A (en) * 1993-06-25 1994-09-20 The Governors Of The University Of Alberta Electrospray interface for mass spectrometer and method of supplying analyte to a mass spectrometer
CA2184982C (en) * 1994-03-08 2004-01-20 Craig Whitehouse Electrospray and atmospheric pressure chemical ionization sources
US5495108A (en) * 1994-07-11 1996-02-27 Hewlett-Packard Company Orthogonal ion sampling for electrospray LC/MS
JP3415682B2 (ja) * 1994-08-10 2003-06-09 株式会社日立製作所 キャピラリー電気泳動・質量分析計
US5545304A (en) * 1995-05-15 1996-08-13 Battelle Memorial Institute Ion current detector for high pressure ion sources for monitoring separations
US5672868A (en) * 1996-02-16 1997-09-30 Varian Associates, Inc. Mass spectrometer system and method for transporting and analyzing ions

Also Published As

Publication number Publication date
ATE488025T1 (de) 2010-11-15
CA2268448C (en) 2006-08-22
CA2268448A1 (en) 1998-03-19
WO1998011595A1 (en) 1998-03-19
US6593568B1 (en) 2003-07-15
EP0925601A4 (de) 2006-08-09
AU4338997A (en) 1998-04-02
EP0925601A1 (de) 1999-06-30
EP0925601B1 (de) 2010-11-10

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