DE69739295D1 - Löslicher, rekombinanter alphaV beta3 Adhäsionsrezeptor - Google Patents

Löslicher, rekombinanter alphaV beta3 Adhäsionsrezeptor

Info

Publication number
DE69739295D1
DE69739295D1 DE69739295T DE69739295T DE69739295D1 DE 69739295 D1 DE69739295 D1 DE 69739295D1 DE 69739295 T DE69739295 T DE 69739295T DE 69739295 T DE69739295 T DE 69739295T DE 69739295 D1 DE69739295 D1 DE 69739295D1
Authority
DE
Germany
Prior art keywords
recombinant
soluble
adhesion receptor
alphav beta3
alphav
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69739295T
Other languages
English (en)
Inventor
Simon L Goodman
Raj Mehta
Beate Diefenbach
Eilish Cullen
Detlev Guessow
Alex Brown
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Application granted granted Critical
Publication of DE69739295D1 publication Critical patent/DE69739295D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70546—Integrin superfamily
    • C07K14/70557—Integrin beta3-subunit-containing molecules, e.g. CD41, CD51, CD61
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69739295T 1996-12-09 1997-11-27 Löslicher, rekombinanter alphaV beta3 Adhäsionsrezeptor Expired - Lifetime DE69739295D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96119700 1996-12-09

Publications (1)

Publication Number Publication Date
DE69739295D1 true DE69739295D1 (de) 2009-04-23

Family

ID=8223479

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69739295T Expired - Lifetime DE69739295D1 (de) 1996-12-09 1997-11-27 Löslicher, rekombinanter alphaV beta3 Adhäsionsrezeptor

Country Status (5)

Country Link
US (2) US20020055136A1 (de)
EP (1) EP0846702B1 (de)
JP (1) JP4349662B2 (de)
DE (1) DE69739295D1 (de)
ES (1) ES2321991T3 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6268215B1 (en) * 1998-11-04 2001-07-31 The Research Foundation Of State University Of New York Recombinant keratinocytes
AU2593600A (en) 1998-12-23 2000-07-12 G.D. Searle & Co. Method of using a cyclooxygenase-2 inhibitor and a matrix metalloproteinase inhibitor as a combination therapy in the treatment of neoplasia
WO2002008280A2 (en) * 2000-07-26 2002-01-31 The Burnham Institute SCREENING METHODS BASED ON SUPERACTIVATED αVβ3 INTEGRIN

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5212071A (en) * 1988-04-01 1993-05-18 The Johns Hopkins University Nucleic acids encoding a human C3b/C4b receptor (CR1)
US4223002A (en) * 1978-08-28 1980-09-16 Hoffmann-La Roche Inc. Isolation of alpha1 -fetoprotein
US4745051A (en) * 1983-05-27 1988-05-17 The Texas A&M University System Method for producing a recombinant baculovirus expression vector
JP3608572B2 (ja) * 1988-12-22 2005-01-12 ジェネンテク，インコーポレイテッド 水溶性ポリペプチドの製造方法
US5298418A (en) * 1991-09-16 1994-03-29 Boyce Thompson Institute For Plant Research, Inc. Cell line isolated from larval midgut tissue of Trichoplusia ni
EP0633945B1 (de) * 1992-04-03 1998-12-30 Genentech, Inc. Antikörper gegen alpha v beta 3 integrin
US5753230A (en) * 1994-03-18 1998-05-19 The Scripps Research Institute Methods and compositions useful for inhibition of angiogenesis
SI0719859T1 (en) * 1994-12-20 2003-12-31 Merck Patent Gmbh Anti-alpha V-integrin monoclonal antibody
EP0854920A4 (de) * 1995-08-31 2002-06-19 Merck & Co Inc Integrin - untereinheiten der maus
US5854205A (en) * 1995-10-23 1998-12-29 The Children's Medical Center Corporation Therapeutic antiangiogenic compositions and methods

Also Published As

Publication number Publication date
EP0846702A2 (de) 1998-06-10
US20050130137A1 (en) 2005-06-16
EP0846702B1 (de) 2009-03-11
US20020055136A1 (en) 2002-05-09
EP0846702A3 (de) 2001-07-18
ES2321991T3 (es) 2009-06-15
US8067197B2 (en) 2011-11-29
JPH10174591A (ja) 1998-06-30
JP4349662B2 (ja) 2009-10-21

Similar Documents

Publication Publication Date Title
ZA974234B (en) Adhesion receptor antagonists.
NO994325D0 (no) TrÕdlöst telefonsystem med PC-basert funksjonalitet
DE69734833D1 (de) Vitronektin rezeptor antagonisten
NO994198L (no) Forbedret cellulaert kommunikasjonssystem
DE69734306D1 (de) Zwei-wege schnurloses Nachrichtensystem
DE69735926D1 (de) Interleukin-18 Rezeptorproteine
NO2010013I2 (no) Rekombinant FSH-CTP
ATE324839T1 (de) Einstufiges implantatsystem
EP1221482A4 (de) NEUES HäMOPOIETINREZEPTOR-PROTEIN, NR12
ID16698A (id) Pengikat cincin
ID16853A (id) Pengikat cincin
EE9900160A (et) Elastne vaheriie
TR199600359A2 (tr) Adezyon reseptörü antagonistleri.
NO950606D0 (no) Adhesjonsreseptor-antagonister
ID24726A (id) Antagonis-antagonis reseptor trombin
DE59707522D1 (de) Biocid ausgerüstetes, faserverstärktes schwammtuch
ID24162A (id) Antagonis-antagonis reseptor vitronektin
DZ2322A1 (fr) Antagonistes de récepteurs de vitronectine.
DE69717300D1 (de) Digitales kommunikationssystem
DE69739295D1 (de) Löslicher, rekombinanter alphaV beta3 Adhäsionsrezeptor
DE19882305T1 (de) Nicht-Phenolische Kautschukklebrigmacher
DE69610613D1 (de) Ring-Ordner
DE69615850D1 (de) G-protein-gekoppelter rezeptor hnfd578
TR199601082A3 (tr) Entegrin reseptör antagonistleri.
DE59703966D1 (de) Schnittstellen-übertrager

Legal Events

Date Code Title Description
8364 No opposition during term of opposition