DE69738888D1 - Bordetella-stamm die eine hybride-fha exprimiert - Google Patents

Bordetella-stamm die eine hybride-fha exprimiert

Info

Publication number
DE69738888D1
DE69738888D1 DE69738888T DE69738888T DE69738888D1 DE 69738888 D1 DE69738888 D1 DE 69738888D1 DE 69738888 T DE69738888 T DE 69738888T DE 69738888 T DE69738888 T DE 69738888T DE 69738888 D1 DE69738888 D1 DE 69738888D1
Authority
DE
Germany
Prior art keywords
fha
protein
expressing
hybrid
bordetella
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69738888T
Other languages
English (en)
Inventor
Nathalie Mielcarek
Camille Locht
Gilles Riveau
Odile Poulain-Godefroy
Andre Capron
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Pasteur de Lille
Institut National de la Sante et de la Recherche Medicale INSERM
Original Assignee
Institut Pasteur de Lille
Institut National de la Sante et de la Recherche Medicale INSERM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut Pasteur de Lille, Institut National de la Sante et de la Recherche Medicale INSERM filed Critical Institut Pasteur de Lille
Application granted granted Critical
Publication of DE69738888D1 publication Critical patent/DE69738888D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/235—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bordetella (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Aiming, Guidance, Guns With A Light Source, Armor, Camouflage, And Targets (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69738888T 1996-10-11 1997-10-09 Bordetella-stamm die eine hybride-fha exprimiert Expired - Lifetime DE69738888D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9612461A FR2754543B1 (fr) 1996-10-11 1996-10-11 Souche de bordetella deficiente dans la production de toxine et exprimant une proteine hydride, liposomes comprenant de la fha et leurs utilisations comme vaccins, et utilisation de la fha pour stimuler les reponses immunitaires
PCT/FR1997/001802 WO1998016553A1 (fr) 1996-10-11 1997-10-09 Souche de bordetella exprimant de la fha hybride, liposomes et vaccins

Publications (1)

Publication Number Publication Date
DE69738888D1 true DE69738888D1 (de) 2008-09-18

Family

ID=9496598

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69738888T Expired - Lifetime DE69738888D1 (de) 1996-10-11 1997-10-09 Bordetella-stamm die eine hybride-fha exprimiert

Country Status (12)

Country Link
US (1) US6660261B1 (de)
EP (1) EP0941241B1 (de)
JP (1) JP4370541B2 (de)
AT (1) ATE403675T1 (de)
AU (1) AU725137B2 (de)
CA (1) CA2267851C (de)
DE (1) DE69738888D1 (de)
DK (1) DK0941241T3 (de)
ES (1) ES2309998T3 (de)
FR (1) FR2754543B1 (de)
PT (1) PT941241E (de)
WO (1) WO1998016553A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ID29082A (id) 1998-09-22 2001-07-26 Molecular Express Inc Komposisi liposom imunogenik
FR2840319B1 (fr) * 2002-05-30 2004-08-20 Pasteur Institut Souches de bordetella rendues deficientes par attenuation genetique
AU2007224734C1 (en) 2006-03-10 2016-07-14 Institut National De La Sante Et De La Recherche Medicale (Inserm) Live attenuated Bordetella strains as a single dose vaccine against whooping cough
AU2010243708C1 (en) 2009-04-28 2014-10-02 Inserm (Institut National De La Sante Et De La Recherche Medicale) Vaccine for prophylaxis or treatment of an allergen-driven airway pathology
EP2442826B1 (de) 2009-06-15 2015-07-08 National University of Singapore Influenzaimpfstoff, zusammensetzung und seine verwendung
WO2013066272A1 (en) 2011-11-02 2013-05-10 National University Of Singapore Effect of an attenuated bordetella strain against allergic disease
EP2722338A1 (de) 2012-10-17 2014-04-23 INSERM (Institut National de la Santé et de la Recherche Médicale) Neue rekombinante Bordetella-Stämme
US9655959B2 (en) 2014-10-01 2017-05-23 National University Of Singapore Adenylate cyclase deficient bordetella strains
CN114767718A (zh) * 2016-03-29 2022-07-22 里尔巴斯德研究所 突变型博德特氏菌属菌株及其使用方法
SG11202003333WA (en) 2017-10-18 2020-05-28 Pasteur Institut Bordetella strains expressing serotype 3 fimbriae

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4563303A (en) * 1984-04-14 1986-01-07 Judicial Foundation The Chemosero-Therapeutic Research Institute Method for purification of filamentous hemagglutinin
FR2590483B1 (fr) * 1985-11-22 1988-12-09 Pasteur Institut Antigenes purifies ayant des proprietes vaccinantes contre b. pertussis, moyens notamment adns recombinants pour les produire et compositions de vaccins les contenant
WO1989001976A1 (en) * 1987-09-04 1989-03-09 Amgen Inc. Recombinant dna-derived bordetella toxin subunit analogs
GB8727489D0 (en) * 1987-11-24 1987-12-23 Connaught Lab Detoxification of pertussis toxin
DD268161A1 (de) * 1987-11-27 1989-05-24 Staatliches Inst Fuer Immunpra Verfahren zur herstellung von bakteriellen antigenen
US6036960A (en) * 1988-10-27 2000-03-14 Relman; David A. Filamentous hemagglutinin of B. pertussis
DK0396964T3 (da) * 1989-04-28 1995-10-30 Sclavo Spa Pertussistoxin-mutanter, Bordetella-stammer, der er i stand til at producere sådanne mutanter, samt deres anvendelse til udvikling af antipertussis-vacciner
GB8910570D0 (en) * 1989-05-08 1989-06-21 Wellcome Found Acellular vaccine
US5786189A (en) * 1989-11-29 1998-07-28 Smithkline Beecham Biologicals (S.A.) Vaccine
EP0471954A3 (en) * 1990-08-13 1993-03-03 American Cyanamid Company Immunogenic conjugates of nontoxic oligosaccharide derived from bordetella pertussis lipooligosaccharide
NL9002092A (nl) * 1990-09-25 1992-04-16 Nederlanden Staat Vaccin, geschikt voor de bestrijding van bordetella pertussis.
FR2718750B1 (fr) * 1994-04-19 1996-06-14 Pasteur Institut Protéines recombinantes de l'hémagglutinine filamenteuse de Bordetella, notamment, B. Pertussis, production et application à la production de protéines étrangères ou de principes actifs vaccinants.
WO2006034129A2 (en) * 2004-09-17 2006-03-30 Jmar Research, Inc. Systems and methods for detecting scattered light from a particle using illumination incident at an angle

Also Published As

Publication number Publication date
DK0941241T3 (da) 2008-11-17
EP0941241B1 (de) 2008-08-06
FR2754543A1 (fr) 1998-04-17
AU4627897A (en) 1998-05-11
CA2267851A1 (fr) 1998-04-23
JP2001507568A (ja) 2001-06-12
AU725137B2 (en) 2000-10-05
WO1998016553A1 (fr) 1998-04-23
US6660261B1 (en) 2003-12-09
CA2267851C (fr) 2011-12-13
FR2754543B1 (fr) 1998-12-31
PT941241E (pt) 2008-10-23
ATE403675T1 (de) 2008-08-15
ES2309998T3 (es) 2008-12-16
JP4370541B2 (ja) 2009-11-25
EP0941241A1 (de) 1999-09-15

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