DE69737815D1 - G-protein gekoppelter rezeptor mit vergrösserter, extrazellulärer domäne - Google Patents

G-protein gekoppelter rezeptor mit vergrösserter, extrazellulärer domäne

Info

Publication number
DE69737815D1
DE69737815D1 DE69737815T DE69737815T DE69737815D1 DE 69737815 D1 DE69737815 D1 DE 69737815D1 DE 69737815 T DE69737815 T DE 69737815T DE 69737815 T DE69737815 T DE 69737815T DE 69737815 D1 DE69737815 D1 DE 69737815D1
Authority
DE
Germany
Prior art keywords
receptor
diseases
coupled receptor
enlarged
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69737815T
Other languages
English (en)
Other versions
DE69737815T2 (de
Inventor
Richard D Ye
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scripps Research Institute
Original Assignee
Scripps Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Institute filed Critical Scripps Research Institute
Publication of DE69737815D1 publication Critical patent/DE69737815D1/de
Application granted granted Critical
Publication of DE69737815T2 publication Critical patent/DE69737815T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69737815T 1996-01-30 1997-01-30 G-protein gekoppelter rezeptor mit vergrösserter, extrazellulärer domäne Expired - Fee Related DE69737815T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1080896P 1996-01-30 1996-01-30
US10808P 1996-01-30
PCT/US1997/001736 WO1997028188A1 (en) 1996-01-30 1997-01-30 A g protein-coupled receptor with an enlarged extracellular domain

Publications (2)

Publication Number Publication Date
DE69737815D1 true DE69737815D1 (de) 2007-07-26
DE69737815T2 DE69737815T2 (de) 2008-03-06

Family

ID=21747533

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69737815T Expired - Fee Related DE69737815T2 (de) 1996-01-30 1997-01-30 G-protein gekoppelter rezeptor mit vergrösserter, extrazellulärer domäne

Country Status (9)

Country Link
US (2) US6521418B1 (de)
EP (1) EP0948536B1 (de)
AT (1) ATE364627T1 (de)
AU (1) AU733853B2 (de)
CA (1) CA2244850A1 (de)
DE (1) DE69737815T2 (de)
DK (1) DK0948536T3 (de)
ES (1) ES2287951T3 (de)
WO (1) WO1997028188A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1087700A (ja) * 1996-06-17 1998-04-07 Smithkline Beecham Corp C3a受容体およびC3aを用いる治療およびスクリーニング方法
WO2000078950A2 (en) * 1999-06-22 2000-12-28 Amylin Pharmaceuticals, Inc. Differentially expressed genes in the adipocytes of obese mice
WO2002001950A2 (en) * 2000-06-29 2002-01-10 Deltagen, Inc. Transgenic mice containing targeted gene disruptions
AUPS271902A0 (en) * 2002-05-31 2002-06-20 Griffith University Gene expression and multiple sclerosis
WO2003106694A2 (en) * 2002-06-13 2003-12-24 New England Medical Center Hospitals, Inc. Rapid methods for assessing therapeutic activity using animals expressing constitutively active g protein-coupled receptors
DE10303974A1 (de) 2003-01-31 2004-08-05 Abbott Gmbh & Co. Kg Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung
WO2004082566A2 (en) * 2003-03-17 2004-09-30 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with complement component 3a receptor 1 (c3ar1)
US20060068426A1 (en) * 2004-08-20 2006-03-30 Tam James P Cyclic peptides and antibodies thereof
KR101667623B1 (ko) 2005-11-30 2016-10-19 애브비 인코포레이티드 아밀로이드 베타 단백질에 대한 모노클로날 항체 및 이의 용도
PL1954718T3 (pl) 2005-11-30 2015-04-30 Abbvie Inc Przeciwciała skierowane przeciwko A globulomerowi, ich reszty wiążące antygeny, odpowiednie hybrydomy, kwasy nukleinowe, wektory, komórki gospodarze, sposoby wytwarzania tych przeciwciał, kompozycje zawierające te przeciwciała, zastosowania tych przeciwciał i sposoby stosowania tych przeciwciał
US8455626B2 (en) 2006-11-30 2013-06-04 Abbott Laboratories Aβ conformer selective anti-aβ globulomer monoclonal antibodies
EP2124952A2 (de) 2007-02-27 2009-12-02 Abbott GmbH & Co. KG Verfahren zur behandlung von amyloidosen
MX336196B (es) 2010-04-15 2016-01-11 Abbvie Inc Proteinas de union a amiloide beta.
MX358739B (es) 2010-08-14 2018-09-03 Abbvie Inc Star Proteinas de union a amiloide beta.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0812329A4 (de) * 1995-02-17 2001-08-29 Human Genome Sciences Inc Menschlicher g-protein gekoppelter rezeptor
US20030027245A1 (en) * 1995-02-17 2003-02-06 Yi Li Human g-protein coupled receptor
WO1996039511A2 (en) * 1995-06-05 1996-12-12 Incyte Pharmaceuticals, Inc. A C5a-LIKE SEVEN TRANSMEMBRANE RECEPTOR
JPH1087700A (ja) * 1996-06-17 1998-04-07 Smithkline Beecham Corp C3a受容体およびC3aを用いる治療およびスクリーニング方法

Also Published As

Publication number Publication date
EP0948536A1 (de) 1999-10-13
ES2287951T3 (es) 2007-12-16
US20030187244A1 (en) 2003-10-02
US6521418B1 (en) 2003-02-18
AU733853B2 (en) 2001-05-31
EP0948536B1 (de) 2007-06-13
WO1997028188A1 (en) 1997-08-07
CA2244850A1 (en) 1997-08-07
AU2256097A (en) 1997-08-22
DE69737815T2 (de) 2008-03-06
DK0948536T3 (da) 2007-10-01
ATE364627T1 (de) 2007-07-15
EP0948536A4 (de) 2001-04-11

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee