DE69733650D1 - System zur gleichzeitigen durchführung von mehrfachligandenbindungstests - Google Patents

System zur gleichzeitigen durchführung von mehrfachligandenbindungstests

Info

Publication number
DE69733650D1
DE69733650D1 DE69733650T DE69733650T DE69733650D1 DE 69733650 D1 DE69733650 D1 DE 69733650D1 DE 69733650 T DE69733650 T DE 69733650T DE 69733650 T DE69733650 T DE 69733650T DE 69733650 D1 DE69733650 D1 DE 69733650D1
Authority
DE
Germany
Prior art keywords
ligand binding
binding tests
simultaneous implementation
multiple ligand
simultaneous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69733650T
Other languages
English (en)
Other versions
DE69733650T2 (de
Inventor
Robert Obremski
W Silzel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beckman Coulter Inc
Original Assignee
Beckman Coulter Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24440692&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69733650(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Beckman Coulter Inc filed Critical Beckman Coulter Inc
Publication of DE69733650D1 publication Critical patent/DE69733650D1/de
Application granted granted Critical
Publication of DE69733650T2 publication Critical patent/DE69733650T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/648—Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE69733650T 1996-03-01 1997-02-24 System zum simultanen Durchführen einer Vielzahl von Ligandenbindungs-Untersuchungen Expired - Fee Related DE69733650T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US60941096A 1996-03-01 1996-03-01
PCT/US1997/002748 WO1997032212A1 (en) 1996-03-01 1997-02-24 System for simultaneously conducting multiple ligand binding assays
US609410 2000-07-03

Publications (2)

Publication Number Publication Date
DE69733650D1 true DE69733650D1 (de) 2005-08-04
DE69733650T2 DE69733650T2 (de) 2006-04-20

Family

ID=24440692

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69733650T Expired - Fee Related DE69733650T2 (de) 1996-03-01 1997-02-24 System zum simultanen Durchführen einer Vielzahl von Ligandenbindungs-Untersuchungen

Country Status (4)

Country Link
US (1) US6110749A (de)
EP (1) EP0904542B1 (de)
DE (1) DE69733650T2 (de)
WO (1) WO1997032212A1 (de)

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DE19838802A1 (de) * 1998-06-22 1999-12-23 Roche Diagnostics Gmbh Verbesserung von Bindeassays durch Multiepitopanalyse und Kombination von Antigen- und Antikörper-Bestimmung
ATE333647T1 (de) * 1998-06-22 2006-08-15 Roche Diagnostics Gmbh Verbesserung von bindeassays durch multiepitopanalyse
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US6192168B1 (en) * 1999-04-09 2001-02-20 The United States Of America As Represented By The Secretary Of The Navy Reflectively coated optical waveguide and fluidics cell integration
US6268141B1 (en) * 1999-05-12 2001-07-31 Beckman Coulter, Inc. Immobilization of unmodified biopolymers to acyl fluoride activated substrates
DE50010710D1 (de) † 1999-08-20 2005-08-18 Diagnostische Forsch Stiftung Verfahren zur bestimmung von substanzen mittels der evaneszenzfeldmethode
AU2001261094A1 (en) 2000-04-28 2001-11-12 Edgelight Biosciences, Inc. Micro-array evanescent wave fluorescence detection device
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US6710877B2 (en) * 2001-07-23 2004-03-23 Corning Incorporated Apparatus and methods for determining biomolecular interactions
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US6707958B2 (en) * 2001-11-20 2004-03-16 Agilent Technologies, Inc. Biochemical assay device using frustrated total internal reflection modulator with an imaging optical waveguide
TWI293363B (en) * 2001-12-11 2008-02-11 Sensors For Med & Science Inc High performance fluorescent optical sensor
JP3668198B2 (ja) * 2002-02-18 2005-07-06 株式会社東芝 光導波路型マイクロプレート
US7179654B2 (en) * 2002-03-18 2007-02-20 Agilent Technologies, Inc. Biochemical assay with programmable array detection
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US20050221279A1 (en) * 2004-04-05 2005-10-06 The Regents Of The University Of California Method for creating chemical sensors using contact-based microdispensing technology
US7768650B2 (en) * 2004-04-21 2010-08-03 Michael Bazylenko Optoelectronic biochip
DE102004039564B4 (de) * 2004-08-13 2006-06-29 Institut für Lasertechnologien in der Medizin und Meßtechnik an der Universität Ulm Vorrichtung zum optischen Screening von Oberflächen biologischer Proben in zweidimensionaler Anordnung
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CN101416042A (zh) * 2006-02-06 2009-04-22 意法半导体股份有限公司 集成波导的核酸分析芯片和用于核酸探针检验的光学设备
US7951583B2 (en) * 2006-03-10 2011-05-31 Plc Diagnostics, Inc. Optical scanning system
US9976192B2 (en) 2006-03-10 2018-05-22 Ldip, Llc Waveguide-based detection system with scanning light source
US9528939B2 (en) 2006-03-10 2016-12-27 Indx Lifecare, Inc. Waveguide-based optical scanning systems
US9423397B2 (en) 2006-03-10 2016-08-23 Indx Lifecare, Inc. Waveguide-based detection system with scanning light source
US8288157B2 (en) 2007-09-12 2012-10-16 Plc Diagnostics, Inc. Waveguide-based optical scanning systems
US7651869B2 (en) * 2006-03-14 2010-01-26 Research International, Inc. Optical assay apparatus and methods
US11001881B2 (en) 2006-08-24 2021-05-11 California Institute Of Technology Methods for detecting analytes
US9133504B2 (en) * 2006-06-05 2015-09-15 California Institute Of Technology Real time microarrays
US8637436B2 (en) * 2006-08-24 2014-01-28 California Institute Of Technology Integrated semiconductor bioarray
US8048626B2 (en) 2006-07-28 2011-11-01 California Institute Of Technology Multiplex Q-PCR arrays
US11525156B2 (en) 2006-07-28 2022-12-13 California Institute Of Technology Multiplex Q-PCR arrays
US11560588B2 (en) 2006-08-24 2023-01-24 California Institute Of Technology Multiplex Q-PCR arrays
EP2116839A1 (de) * 2008-05-09 2009-11-11 Université Catholique de Louvain Vorrichtung für mehrfache ATR-Analyse
GB2461026B (en) 2008-06-16 2011-03-09 Plc Diagnostics Inc System and method for nucleic acids sequencing by phased synthesis
JP5757535B2 (ja) 2009-04-29 2015-07-29 ピーエルシー ダイアグノスティクス， インコーポレイテッド 走査光源による導波管に基づく検出システム
US10018566B2 (en) 2014-02-28 2018-07-10 Ldip, Llc Partially encapsulated waveguide based sensing chips, systems and methods of use
US11181479B2 (en) 2015-02-27 2021-11-23 Ldip, Llc Waveguide-based detection system with scanning light source
US9708647B2 (en) 2015-03-23 2017-07-18 Insilixa, Inc. Multiplexed analysis of nucleic acid hybridization thermodynamics using integrated arrays
US9499861B1 (en) 2015-09-10 2016-11-22 Insilixa, Inc. Methods and systems for multiplex quantitative nucleic acid amplification
WO2017155858A1 (en) 2016-03-07 2017-09-14 Insilixa, Inc. Nucleic acid sequence identification using solid-phase cyclic single base extension
WO2018002205A1 (en) * 2016-06-29 2018-01-04 Koninklijke Philips N.V. Light guides with coating to be used in water
EP3594663A4 (de) * 2017-04-14 2020-12-30 National Institute of Advanced Industrial Science and Technology Chip zum nachweis von gewünschten substanzen, vorrichtung zum nachweis von gewünschten substanzen und verfahren zum nachweis von gewünschten substanzen
US20200256797A1 (en) * 2017-10-04 2020-08-13 Unisensor Diagnostic means for the detection and/or quantification of a plurality of analytes present in a sample
JP2022525322A (ja) 2019-03-14 2022-05-12 インシリクサ， インコーポレイテッド 時間ゲート蛍光ベースの検出のための方法およびシステム
EP4089401B1 (de) * 2021-05-10 2024-11-06 Siemens Aktiengesellschaft Messeinrichtung und verfahren zur messung von mindestens zwei verschiedenen komponenten eines fluids mittels ramanstreuung und chemilumineszenz
WO2024056862A1 (en) 2022-09-15 2024-03-21 Avidicure Ip B.V. Multispecific antigen binding proteins for tumor-targeting of nk cells and use thereof

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Also Published As

Publication number Publication date
DE69733650T2 (de) 2006-04-20
WO1997032212A1 (en) 1997-09-04
EP0904542A1 (de) 1999-03-31
EP0904542B1 (de) 2005-06-29
US6110749A (en) 2000-08-29

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8339 Ceased/non-payment of the annual fee