DE69732230D1 - Durch lymphe absorbierbare imidazolderivate - Google Patents

Durch lymphe absorbierbare imidazolderivate

Info

Publication number
DE69732230D1
DE69732230D1 DE69732230T DE69732230T DE69732230D1 DE 69732230 D1 DE69732230 D1 DE 69732230D1 DE 69732230 T DE69732230 T DE 69732230T DE 69732230 T DE69732230 T DE 69732230T DE 69732230 D1 DE69732230 D1 DE 69732230D1
Authority
DE
Germany
Prior art keywords
lymphic
absorbable
imidazole derivatives
lymph
hydrate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69732230T
Other languages
English (en)
Other versions
DE69732230T2 (de
Inventor
Katsutoshi Aono
Teruhisa Ichihashi
Tamio Sugawara
Koichiro Hirano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Publication of DE69732230D1 publication Critical patent/DE69732230D1/de
Application granted granted Critical
Publication of DE69732230T2 publication Critical patent/DE69732230T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69732230T 1996-03-28 1997-03-14 Durch lymphe absorbierbare imidazolderivate Expired - Fee Related DE69732230T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP10329996 1996-03-28
JP10329996 1996-03-28
PCT/JP1997/000813 WO1997035843A1 (fr) 1996-03-28 1997-03-14 Derives d'imidazole absorbables par la lymphe

Publications (2)

Publication Number Publication Date
DE69732230D1 true DE69732230D1 (de) 2005-02-17
DE69732230T2 DE69732230T2 (de) 2005-12-22

Family

ID=14350384

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69732230T Expired - Fee Related DE69732230T2 (de) 1996-03-28 1997-03-14 Durch lymphe absorbierbare imidazolderivate

Country Status (7)

Country Link
US (1) US6054591A (de)
EP (1) EP0893442B1 (de)
AT (1) ATE286884T1 (de)
AU (1) AU1940897A (de)
DE (1) DE69732230T2 (de)
TW (1) TW467904B (de)
WO (1) WO1997035843A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602004026289D1 (de) 2003-05-05 2010-05-12 Probiodrug Ag Glutaminylcyclase-hemmer
EP2903609B1 (de) * 2012-10-05 2017-12-06 NeuroVive Pharmaceutical AB Geschützte succinate zur verbesserung der mitochondrialen atp-produktion
EP3180349A4 (de) * 2014-08-12 2018-08-22 Monash University Lymphenleitungsprodrugs
WO2017041139A1 (en) 2015-09-08 2017-03-16 Monash University Lymph directing prodrugs
US11883497B2 (en) 2017-08-29 2024-01-30 Puretech Lyt, Inc. Lymphatic system-directing lipid prodrugs
BR112020004729A2 (pt) * 2017-09-20 2020-09-15 Kao Corporation composição em pó compreendendo corantes diretos para o cabelo
US11304954B2 (en) 2017-12-19 2022-04-19 Puretech Lyt, Inc. Lipid prodrugs of mycophenolic acid and uses thereof
US11608345B1 (en) 2017-12-19 2023-03-21 Puretech Lyt, Inc. Lipid prodrugs of rapamycin and its analogs and uses thereof
EP4100017A4 (de) 2020-02-05 2024-04-10 Puretech Lyt Inc Lipidprodrugs von neurosteroiden

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5216142A (en) * 1989-04-17 1993-06-01 Efamol Holdings Plc Anti-virals
TW235963B (de) * 1992-01-16 1994-12-11 Shionogi & Co
MX9702030A (es) * 1994-09-26 1997-06-28 Shionogi & Co Derivado de imidazol.

Also Published As

Publication number Publication date
US6054591A (en) 2000-04-25
WO1997035843A1 (fr) 1997-10-02
EP0893442A1 (de) 1999-01-27
EP0893442A4 (de) 2002-07-17
AU1940897A (en) 1997-10-17
DE69732230T2 (de) 2005-12-22
ATE286884T1 (de) 2005-01-15
EP0893442B1 (de) 2005-01-12
TW467904B (en) 2001-12-11

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee