DE69729740D1 - Cytotrienin-verbindungen, verfahren zu ihrer herstellung und antitumor-mittel - Google Patents

Cytotrienin-verbindungen, verfahren zu ihrer herstellung und antitumor-mittel

Info

Publication number
DE69729740D1
DE69729740D1 DE69729740T DE69729740T DE69729740D1 DE 69729740 D1 DE69729740 D1 DE 69729740D1 DE 69729740 T DE69729740 T DE 69729740T DE 69729740 T DE69729740 T DE 69729740T DE 69729740 D1 DE69729740 D1 DE 69729740D1
Authority
DE
Germany
Prior art keywords
cytotrienin
compounds
production
antitumor agents
antitumor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69729740T
Other languages
English (en)
Other versions
DE69729740T2 (de
Inventor
Hiroyuki-The Ins Of Phys Osada
Hideaki-The Inst Of Phy Kakeya
Hui-Ping-The Inst Of Phy Zhang
Kimie-The Ins Of Phys Kobinata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RIKEN Institute of Physical and Chemical Research
Original Assignee
RIKEN Institute of Physical and Chemical Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by RIKEN Institute of Physical and Chemical Research filed Critical RIKEN Institute of Physical and Chemical Research
Publication of DE69729740D1 publication Critical patent/DE69729740D1/de
Application granted granted Critical
Publication of DE69729740T2 publication Critical patent/DE69729740T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D225/00—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
    • C07D225/04—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D225/06—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
DE69729740T 1996-11-29 1997-12-01 Cytotrienin-verbindungen, verfahren zu ihrer herstellung und antitumor-mittel Expired - Fee Related DE69729740T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP32024196A JP3726980B2 (ja) 1996-11-29 1996-11-29 サイトトリエニン類、その製造方法および抗腫瘍剤
JP32024196 1996-11-29
PCT/JP1997/004374 WO1998023594A1 (fr) 1996-11-29 1997-12-01 Cytotrienines, leur procede de preparation et agent antitumoral

Publications (2)

Publication Number Publication Date
DE69729740D1 true DE69729740D1 (de) 2004-08-05
DE69729740T2 DE69729740T2 (de) 2005-07-14

Family

ID=18119305

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69729740T Expired - Fee Related DE69729740T2 (de) 1996-11-29 1997-12-01 Cytotrienin-verbindungen, verfahren zu ihrer herstellung und antitumor-mittel

Country Status (5)

Country Link
US (1) US6251885B1 (de)
EP (1) EP0945436B1 (de)
JP (1) JP3726980B2 (de)
DE (1) DE69729740T2 (de)
WO (1) WO1998023594A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3726980B2 (ja) 1996-11-29 2005-12-14 独立行政法人理化学研究所 サイトトリエニン類、その製造方法および抗腫瘍剤

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5894393A (ja) * 1981-11-27 1983-06-04 Nisshin Flour Milling Co Ltd 抗腫瘍性物質の製法
US4521339A (en) * 1981-11-27 1985-06-04 Nisshin Flour Milling Co., Ltd. Ansatrienols
JP2641906B2 (ja) * 1988-06-30 1997-08-20 日清製粉株式会社 マイコトリエニン系化合物
EP0739883A4 (de) * 1994-11-15 1997-04-02 Kyowa Hakko Kogyo Kk Ucf116 verbindungen
JP3726980B2 (ja) 1996-11-29 2005-12-14 独立行政法人理化学研究所 サイトトリエニン類、その製造方法および抗腫瘍剤

Also Published As

Publication number Publication date
EP0945436A4 (de) 1999-12-15
EP0945436A1 (de) 1999-09-29
US6251885B1 (en) 2001-06-26
WO1998023594A1 (fr) 1998-06-04
JPH10158245A (ja) 1998-06-16
EP0945436B1 (de) 2004-06-30
JP3726980B2 (ja) 2005-12-14
DE69729740T2 (de) 2005-07-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee