DE69728529D1 - Cytokinantagonisten und -agonisten - Google Patents
Cytokinantagonisten und -agonistenInfo
- Publication number
- DE69728529D1 DE69728529D1 DE69728529T DE69728529T DE69728529D1 DE 69728529 D1 DE69728529 D1 DE 69728529D1 DE 69728529 T DE69728529 T DE 69728529T DE 69728529 T DE69728529 T DE 69728529T DE 69728529 D1 DE69728529 D1 DE 69728529D1
- Authority
- DE
- Germany
- Prior art keywords
- binding
- csf
- receptors
- loop
- chain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 108090000695 Cytokines Proteins 0.000 title abstract 3
- 102000004127 Cytokines Human genes 0.000 title abstract 3
- 239000000556 agonist Substances 0.000 title 1
- 239000005557 antagonist Substances 0.000 title 1
- 108010017213 Granulocyte-Macrophage Colony-Stimulating Factor Proteins 0.000 abstract 2
- 102000004457 Granulocyte-Macrophage Colony-Stimulating Factor Human genes 0.000 abstract 2
- 108010002386 Interleukin-3 Proteins 0.000 abstract 2
- 108010002616 Interleukin-5 Proteins 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000002209 hydrophobic effect Effects 0.000 abstract 1
- 230000000638 stimulation Effects 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7153—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for colony-stimulating factors [CSF]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPN780096 | 1996-01-30 | ||
AUPN7800A AUPN780096A0 (en) | 1996-01-30 | 1996-01-30 | Cytokine antagonists and agonists |
PCT/AU1997/000049 WO1997028190A1 (en) | 1996-01-30 | 1997-01-29 | Cytokine antagonists and agonists |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69728529D1 true DE69728529D1 (de) | 2004-05-13 |
DE69728529T2 DE69728529T2 (de) | 2005-04-14 |
Family
ID=3792117
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69728529T Expired - Lifetime DE69728529T2 (de) | 1996-01-30 | 1997-01-29 | Cytokinantagonisten und -agonisten |
Country Status (7)
Country | Link |
---|---|
US (2) | USRE39433E1 (de) |
EP (2) | EP0889905B1 (de) |
JP (1) | JP2000505420A (de) |
AT (1) | ATE263783T1 (de) |
AU (1) | AUPN780096A0 (de) |
DE (1) | DE69728529T2 (de) |
WO (1) | WO1997028190A1 (de) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2001511649A (ja) * | 1997-02-07 | 2001-08-14 | トーマス・ジェファーソン・ユニバーシティ | サイトカインレセプターガンマ鎖のペプチド模倣物 |
AU9289098A (en) * | 1997-09-23 | 1999-04-12 | Astra Aktiebolag | Inhibitors of hematopoietins interleukin-3, interleukin-5 and granulocyte/macrophage colony stimulating factor and uses thereof |
CA2235420A1 (en) * | 1998-06-17 | 1999-12-17 | Paolo Renzi | Antisense oligonucleotides for treating or preventing atopic diseases and neoplastic cell proliferation |
AUPP525198A0 (en) * | 1998-08-13 | 1998-09-03 | Medvet Science Pty. Ltd. | Monoclonal antibody inhibitor of GM-CSF, IL-3 and IL-5 and other cytokines and uses thereof |
JP2002541061A (ja) | 1999-02-08 | 2002-12-03 | メドベット・サイエンス・プロプライエタリー・リミテッド | サイトカイン結合ドメイン |
EP1216037A2 (de) | 1999-09-21 | 2002-06-26 | Emory University | Verfahren und zusammensetzungen zur behandlung von bluttplätchen-zusammenhängenden krankheiten, mit mpl hemmenden agenten |
US7455836B2 (en) | 2000-05-08 | 2008-11-25 | The University Of Melbourne | Method of treatment and agents useful for same |
US8062637B2 (en) | 2000-05-08 | 2011-11-22 | Morphosys Ag | Methods of ameliorating inflammatory disease using an uPA antagonist |
US20030072737A1 (en) * | 2000-12-29 | 2003-04-17 | Michael Brines | Tissue protective cytokines for the protection, restoration, and enhancement of responsive cells, tissues and organs |
US7767643B2 (en) | 2000-12-29 | 2010-08-03 | The Kenneth S. Warren Institute, Inc. | Protection, restoration, and enhancement of erythropoietin-responsive cells, tissues and organs |
US7718363B2 (en) | 2003-04-25 | 2010-05-18 | The Kenneth S. Warren Institute, Inc. | Tissue protective cytokine receptor complex and assays for identifying tissue protective compounds |
US20060216757A1 (en) * | 2003-04-25 | 2006-09-28 | The Kenneth S. Warren Institute, Inc. | Tissue protective cytokine receptor complex, assays for identifying tissue protective compounds and uses thereof |
WO2006045202A1 (en) | 2004-10-29 | 2006-05-04 | Topigen Pharmaceuticals Inc. | Antisense oligonucleotides for treating allergy and neoplastic cell proliferation |
KR101481844B1 (ko) * | 2006-03-27 | 2015-01-13 | 메디뮨 리미티드 | Gm-csf 수용체에 대한 결합 성분 |
WO2008085963A1 (en) * | 2007-01-05 | 2008-07-17 | University Of Florida Research Foundation, Inc. | Materials and methods for the detection, prevention and treatment of autoimmune disease |
US20100260744A1 (en) * | 2007-07-11 | 2010-10-14 | Medvet Science Pty Ltd. | Regulating il-4 and il-13 levels by blocking high affinity binding by il-3, il-5 and gm-csf to their common receptor |
TW200918553A (en) | 2007-09-18 | 2009-05-01 | Amgen Inc | Human GM-CSF antigen binding proteins |
US20100209341A1 (en) * | 2009-02-18 | 2010-08-19 | Csl Limited | Treatment of chronic inflammatory conditions |
WO2013072901A2 (en) * | 2011-11-17 | 2013-05-23 | Btm Mazowsze Sp. Zo.O. | Compositions and methods for treating glioma |
WO2013090989A1 (en) | 2011-12-22 | 2013-06-27 | Csl Limited | Method of treating inflammatory bowel disease |
KR101676690B1 (ko) * | 2015-08-04 | 2016-11-16 | (주) 에빅스젠 | Vegf 유도-혈관신생 억제효과를 갖는 테트라펩티드 및 이의 용도 |
TWI824372B (zh) * | 2015-10-12 | 2023-12-01 | 美商再生元醫藥公司 | 活化瘦素受體的抗原結合蛋白 |
-
1996
- 1996-01-30 AU AUPN7800A patent/AUPN780096A0/en not_active Abandoned
-
1997
- 1997-01-29 US US10/386,813 patent/USRE39433E1/en not_active Expired - Lifetime
- 1997-01-29 EP EP97901476A patent/EP0889905B1/de not_active Expired - Lifetime
- 1997-01-29 JP JP9527177A patent/JP2000505420A/ja active Pending
- 1997-01-29 EP EP03076937A patent/EP1386933A1/de not_active Withdrawn
- 1997-01-29 US US09/117,399 patent/US6200567B1/en not_active Expired - Lifetime
- 1997-01-29 WO PCT/AU1997/000049 patent/WO1997028190A1/en active IP Right Grant
- 1997-01-29 DE DE69728529T patent/DE69728529T2/de not_active Expired - Lifetime
- 1997-01-29 AT AT97901476T patent/ATE263783T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE69728529T2 (de) | 2005-04-14 |
JP2000505420A (ja) | 2000-05-09 |
US6200567B1 (en) | 2001-03-13 |
EP0889905A4 (de) | 2000-06-07 |
ATE263783T1 (de) | 2004-04-15 |
EP0889905A1 (de) | 1999-01-13 |
EP0889905B1 (de) | 2004-04-07 |
WO1997028190A1 (en) | 1997-08-07 |
AUPN780096A0 (en) | 1996-02-22 |
EP1386933A1 (de) | 2004-02-04 |
USRE39433E1 (en) | 2006-12-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |