DE69721557D1 - Wasserlösliches arabinogalactan, das mit lipophilen gruppen derivatisiert ist - Google Patents

Wasserlösliches arabinogalactan, das mit lipophilen gruppen derivatisiert ist

Info

Publication number
DE69721557D1
DE69721557D1 DE69721557T DE69721557T DE69721557D1 DE 69721557 D1 DE69721557 D1 DE 69721557D1 DE 69721557 T DE69721557 T DE 69721557T DE 69721557 T DE69721557 T DE 69721557T DE 69721557 D1 DE69721557 D1 DE 69721557D1
Authority
DE
Germany
Prior art keywords
arabinogalactans
lipidated
arabinogalactan
groups
derivatized
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69721557T
Other languages
English (en)
Inventor
Geoffrey N Richards
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Montana
Original Assignee
University of Montana
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Montana filed Critical University of Montana
Application granted granted Critical
Publication of DE69721557D1 publication Critical patent/DE69721557D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DE69721557T 1996-11-20 1997-11-20 Wasserlösliches arabinogalactan, das mit lipophilen gruppen derivatisiert ist Expired - Lifetime DE69721557D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/754,225 US6303584B1 (en) 1996-11-20 1996-11-20 Water soluble lipidated arabinogalactan
PCT/US1997/021497 WO1998022512A1 (en) 1996-11-20 1997-11-20 Water soluble lipidated arabinogalactan

Publications (1)

Publication Number Publication Date
DE69721557D1 true DE69721557D1 (de) 2003-06-05

Family

ID=25033934

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69721557T Expired - Lifetime DE69721557D1 (de) 1996-11-20 1997-11-20 Wasserlösliches arabinogalactan, das mit lipophilen gruppen derivatisiert ist

Country Status (7)

Country Link
US (3) US6303584B1 (de)
EP (1) EP0939771B1 (de)
AT (1) ATE239042T1 (de)
AU (1) AU736535B2 (de)
CA (1) CA2272362A1 (de)
DE (1) DE69721557D1 (de)
WO (1) WO1998022512A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6929807B1 (en) * 1996-08-09 2005-08-16 Mannatech, Inc. Compositions of plant carbohydrates as dietary supplements
AU760065B2 (en) * 1998-04-27 2003-05-08 Larex, Inc. Derivatives of arabinogalactan and compositions including the same
US6706295B2 (en) 2000-09-29 2004-03-16 The Procter & Gamble Co. Compositions comprising arabinogalactan and a defined protein component
US6703056B2 (en) 2000-09-29 2004-03-09 The Procter + Gamble Co. Beverage compositions comprising arabinogalactan and defined minerals
US6455512B1 (en) * 2001-03-05 2002-09-24 Tic Gums, Inc. Water-soluble esterified hydrocolloids
US7266151B2 (en) 2002-09-04 2007-09-04 Intel Corporation Method and system for performing motion estimation using logarithmic search
US20050158329A1 (en) * 2004-01-21 2005-07-21 Ghosh Swapan K. Novel phytol derived immunoadjuvants and their use in vaccine formulations
CA2674269C (en) * 2006-01-03 2018-06-12 University Of Georgia Research Foundation, Inc. Three component glycolipopeptides
CA2747569A1 (en) * 2007-12-21 2009-07-02 University Of Graz Use larch wood material for treating inflammation
MX2010014078A (es) * 2008-06-25 2011-04-11 Braasch Biotech Llc Composiciones y metodos para inmunogenecidad mejorada de somatostatina.
US20120039984A1 (en) 2008-07-03 2012-02-16 University Of Georgia Research Foundation, Inc. Glycopeptide and uses thereof
FR2938192B1 (fr) 2008-11-07 2012-08-24 Expanscience Lab Nouvel actif anti-vergetures et compositions le comprenant
US8784844B2 (en) 2009-09-30 2014-07-22 Lonza Ltd. Arabinogalactan for enhancing the adaptive immune response
EP2327411A1 (de) * 2009-11-27 2011-06-01 Lonza Ltd. Arabinogalactan als Immunverstärker
US8609159B2 (en) 2010-05-05 2013-12-17 Comvita New Zealand Limited Immunostimulatory compositions and methods of use thereof
US9393259B2 (en) 2013-03-21 2016-07-19 Lonza Ltd. Composition comprising arabinogalactan and polyphenols from larch trees
US10994013B2 (en) 2013-04-24 2021-05-04 Temple University—Of the Commonwealth System of Higher Education Solid dosage form containing arabinogalactan

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58190365A (ja) 1982-04-30 1983-11-07 Ajinomoto Co Inc 冷凍フライ様食品の製造法
US4966892A (en) 1982-05-07 1990-10-30 Carrington Laboratories, Inc. Processes for preparation of aloe products products produced thereby and compositions thereof
US4917890A (en) 1985-06-28 1990-04-17 Carrington Laboratories, Inc. Processes for preparation of aloe products, products produced thereby and compositions thereof
US5118673A (en) 1982-05-07 1992-06-02 Carrington Laboratories, Inc. Uses of aloe products
US4851224A (en) 1986-06-05 1989-07-25 Carrington Laboratories, Inc. Process for preparation of aloe products
US5443830A (en) 1982-05-07 1995-08-22 Carrington Laboratories, Inc. Drink containing mucilaginous polysaccharides and its preparation
US4735935A (en) 1985-12-17 1988-04-05 Carrington Laboratories, Inc. Process for preparation of aloe products products, produced thereby and compositions thereof
US5106616A (en) 1988-01-14 1992-04-21 Carrington Laboratories, Inc. Administration of acemannan
US5308838A (en) 1982-05-07 1994-05-03 Carrington Laboratories, Inc. Uses of aloe products
SE456911B (sv) 1983-12-19 1988-11-14 Olle Larm Vattenloeslig, aminerad beta-1,3-bunden d-glukan och makrofagstimulerande komposition innehaallande densamma
JPS60233560A (ja) 1984-05-02 1985-11-20 Fujirebio Inc リパ−ゼ活性の測定方法
US4959214A (en) 1985-06-28 1990-09-25 Carrington Laboratories Inc. Processes for preparation of aloe products products produced thereby and compositions thereof
US4957907A (en) 1985-06-28 1990-09-18 Carrington Laboratories Inc. Process for preparation of aloe products
US4877611A (en) 1986-04-15 1989-10-31 Ribi Immunochem Research Inc. Vaccine containing tumor antigens and adjuvants
US5554386A (en) 1986-07-03 1996-09-10 Advanced Magnetics, Inc. Delivery of therapeutic agents to receptors using polysaccharides
JPH0678363B2 (ja) 1987-08-24 1994-10-05 財団法人杉山産業化学研究所 水溶性澱粉脂肪酸エステルの製造方法
US5116969B1 (en) 1990-04-26 1997-04-01 Larex International Inc Ultrarefined arabinogalactan product
AU2254192A (en) 1991-06-24 1993-01-25 Carrington Laboratories, Inc. Wound cleanser
GB2260333A (en) 1991-10-11 1993-04-14 John Mark Lawther Wax-like polysaccharide derivatives
DE4136325A1 (de) 1991-11-05 1993-05-13 Hoechst Ag Cyclodextrinderivate als adsorptionsmittel fuer gallensaeure, mit gallensaeuren beladene cyclodextrinderivate und verfahren zu deren herstellung sowie deren anwendung als arzneimittel
WO1993008810A1 (en) 1991-11-05 1993-05-13 Carrington Laboratories, Inc. Uses of aloe products, e.g. acemannan, in the treatment of diseases requiring intervention of the immune system for cure
WO1993025239A1 (en) 1992-06-17 1993-12-23 Advanced Magnetics Inc. Arabinogalactan derivatives and uses thereof
US5409703A (en) 1993-06-24 1995-04-25 Carrington Laboratories, Inc. Dried hydrogel from hydrophilic-hygroscopic polymer
AU8129894A (en) 1993-11-01 1995-05-23 Alpha-Beta Technology, Inc. Derivatized polysaccharide bile acid sequestrant for reducing cholesterol
JPH10508580A (ja) 1994-09-20 1998-08-25 ファルマシア・アンド・アップジョン・カンパニー Eおよびpセレクチンに対するリガンドのオリゴ糖構造
US5882520A (en) 1995-10-26 1999-03-16 The University Of Montana Use of arabinogalactan in aqueous two phase extractions
US5756098A (en) 1995-12-12 1998-05-26 The University Of Montana Methods for the extraction of phytochemicals from fibrous plants in the absence of solvent

Also Published As

Publication number Publication date
AU5266598A (en) 1998-06-10
EP0939771A1 (de) 1999-09-08
WO1998022512A1 (en) 1998-05-28
EP0939771B1 (de) 2003-05-02
AU736535B2 (en) 2001-08-02
US6258796B1 (en) 2001-07-10
US20010036933A1 (en) 2001-11-01
US6303584B1 (en) 2001-10-16
CA2272362A1 (en) 1998-05-28
ATE239042T1 (de) 2003-05-15

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Legal Events

Date Code Title Description
8332 No legal effect for de