DE69720283T2 - Bestimmung der krebsanfälligkeit eines organs oder gewebes durch bestimmung seiner zellprägung - Google Patents
Bestimmung der krebsanfälligkeit eines organs oder gewebes durch bestimmung seiner zellprägung Download PDFInfo
- Publication number
- DE69720283T2 DE69720283T2 DE69720283T DE69720283T DE69720283T2 DE 69720283 T2 DE69720283 T2 DE 69720283T2 DE 69720283 T DE69720283 T DE 69720283T DE 69720283 T DE69720283 T DE 69720283T DE 69720283 T2 DE69720283 T2 DE 69720283T2
- Authority
- DE
- Germany
- Prior art keywords
- imprinting
- methods
- restoring
- normal
- compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3409596P | 1996-12-30 | 1996-12-30 | |
PCT/US1997/023991 WO1998029108A2 (en) | 1996-12-30 | 1997-12-29 | Compositions and methods for restoring a normal pattern of imprinting to cells |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69720283D1 DE69720283D1 (de) | 2003-04-30 |
DE69720283T2 true DE69720283T2 (de) | 2004-01-29 |
Family
ID=21874277
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69720283T Expired - Lifetime DE69720283T2 (de) | 1996-12-30 | 1997-12-29 | Bestimmung der krebsanfälligkeit eines organs oder gewebes durch bestimmung seiner zellprägung |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP0969822B1 (de) |
JP (2) | JP4913270B2 (de) |
AT (1) | ATE235190T1 (de) |
AU (1) | AU5722398A (de) |
CA (1) | CA2276306C (de) |
DE (1) | DE69720283T2 (de) |
DK (1) | DK0969822T3 (de) |
ES (1) | ES2195196T3 (de) |
WO (1) | WO1998029108A2 (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6803195B1 (en) * | 1999-07-02 | 2004-10-12 | Ramot At Tel-Aviv University Ltd. | Facile detection of cancer and cancer risk based on level of coordination between alleles |
GB0107267D0 (en) * | 2001-03-23 | 2001-05-16 | Babraham Inst | Diagnostic method for determining the methylation state of cloned embryos |
US6982253B2 (en) | 2002-06-05 | 2006-01-03 | Supergen, Inc. | Liquid formulation of decitabine and use of the same |
AU2002952944A0 (en) * | 2002-11-27 | 2002-12-12 | Human Genetic Signatures Pty Ltd | Restoration of methylation states in cells |
US7799525B2 (en) | 2003-06-17 | 2010-09-21 | Human Genetic Signatures Pty Ltd. | Methods for genome amplification |
WO2005024053A1 (en) | 2003-09-04 | 2005-03-17 | Human Genetic Signatures Pty Ltd | Nucleic acid detection assay |
US8168777B2 (en) | 2004-04-29 | 2012-05-01 | Human Genetic Signatures Pty. Ltd. | Bisulphite reagent treatment of nucleic acid |
WO2006026828A1 (en) | 2004-09-10 | 2006-03-16 | Human Genetic Signatures Pty Ltd | Amplification blocker comprising intercalating nucleic acids (tna) containing intercalating pseudonucleotides (ipn) |
NZ555620A (en) | 2004-12-03 | 2008-08-29 | Human Genetic Signatures Pty | Methods for simplifying microbial nucleic acids by chemical modification of cytosines |
AU2006251866B2 (en) | 2005-05-26 | 2007-11-29 | Human Genetic Signatures Pty Ltd | Isothermal strand displacement amplification using primers containing a non-regular base |
US8343738B2 (en) | 2005-09-14 | 2013-01-01 | Human Genetic Signatures Pty. Ltd. | Assay for screening for potential cervical cancer |
GB0607063D0 (en) | 2006-04-07 | 2006-05-17 | Cellcentric Ltd | Compositions and methods for epigenetic modification of nucleic acid sequences in vivo |
EP2215250B1 (de) | 2007-11-27 | 2013-02-27 | Human Genetic Signatures Pty Ltd | Enzyme zur amplifikation und zum kopieren bisulphit-modifizierter nukleinsäuren |
CN103874766B (zh) | 2011-09-07 | 2017-07-18 | 人类遗传标记控股有限公司 | 分子检测测定 |
WO2018214249A1 (zh) | 2017-05-22 | 2018-11-29 | 立森印迹诊断技术(无锡)有限公司 | 一种印记基因分级模型及其组成的系统和应用 |
CN112313345B (zh) * | 2018-05-18 | 2024-02-20 | 立森印迹诊断技术(无锡)有限公司 | 一种通过活检细胞样本诊断癌症的方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58177949A (ja) * | 1982-04-12 | 1983-10-18 | Takeda Chem Ind Ltd | ランカシジン群抗生物質包接化合物 |
JPS61176523A (ja) * | 1985-01-30 | 1986-08-08 | Teruhiko Beppu | 制癌剤 |
EP0631584A4 (de) * | 1991-02-28 | 1998-07-01 | Dana Farber Cancer Inst Inc | Krebs diagnose und therapie. |
EP0627436A1 (de) * | 1991-08-08 | 1994-12-07 | TSUMURA & CO. | Carcinostatische verbindungen und ihre herstellung |
US5356903A (en) * | 1993-04-22 | 1994-10-18 | Sterling Winthrop Inc. | 1-cyclopropyl-4-pyridyl-quinolines |
-
1997
- 1997-12-29 CA CA002276306A patent/CA2276306C/en not_active Expired - Lifetime
- 1997-12-29 AT AT97953486T patent/ATE235190T1/de not_active IP Right Cessation
- 1997-12-29 WO PCT/US1997/023991 patent/WO1998029108A2/en active IP Right Grant
- 1997-12-29 EP EP97953486A patent/EP0969822B1/de not_active Expired - Lifetime
- 1997-12-29 AU AU57223/98A patent/AU5722398A/en not_active Abandoned
- 1997-12-29 ES ES97953486T patent/ES2195196T3/es not_active Expired - Lifetime
- 1997-12-29 DE DE69720283T patent/DE69720283T2/de not_active Expired - Lifetime
- 1997-12-29 DK DK97953486T patent/DK0969822T3/da active
- 1997-12-29 JP JP53025498A patent/JP4913270B2/ja not_active Expired - Lifetime
-
2008
- 2008-10-23 JP JP2008272942A patent/JP2009072197A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2009072197A (ja) | 2009-04-09 |
CA2276306C (en) | 2009-12-15 |
EP0969822B1 (de) | 2003-03-26 |
EP0969822A2 (de) | 2000-01-12 |
ATE235190T1 (de) | 2003-04-15 |
WO1998029108A3 (en) | 1999-02-18 |
DK0969822T3 (da) | 2003-07-21 |
DE69720283D1 (de) | 2003-04-30 |
WO1998029108A2 (en) | 1998-07-09 |
AU5722398A (en) | 1998-07-31 |
JP2001507703A (ja) | 2001-06-12 |
ES2195196T3 (es) | 2003-12-01 |
CA2276306A1 (en) | 1998-07-09 |
JP4913270B2 (ja) | 2012-04-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69720283D1 (de) | Bestimmung der krebsanfälligkeit eines organs oder gewebes durch bestimmung seiner zellprägung | |
Tasmuth et al. | Chronic post-treatment symptoms in patients with breast cancer operated in different surgical units | |
Salman et al. | Actinic lichen planus: a clinicopathologic study of 16 patients | |
DE69725293D1 (de) | N-(2 oxoacetyl oder sulphonyl)-pyrrolidine/piperidine-2-carbonsäurederivate mit verbesserter multi-drug resistenz aktivität | |
HUP0302549A2 (hu) | Eritropoietin-érzékeny sejtek, szövetek és szervek védelme, helyreállítása és növelése | |
ATE173155T1 (de) | Mittel zur künstlichen bräunung mit verbesserter stabilität | |
ES2123714T3 (es) | Aislamiento y estructura de las esponjistatinas 5,7,8 y 9 y su empleo como agentes antitumorales. | |
HK1074486A1 (en) | Oxaliplatin anti-resistance method | |
Frenk et al. | Neurofibromatosis of von Recklinghausen: a quantitative study of the epidermal keratinocyte and melanocyte populations | |
Lumerman et al. | Intraoral (submucosal) pseudosarcomatous nodular fasciitis: report of a case | |
Kanerva et al. | Hyperpigmentation and Hypopigmentation of the Skin after Long Term PUVA Therapy: Light and electron microscopic observations on three patients | |
WO1999045103A3 (en) | Human spinal cord cell lines and methods of use therefor | |
EP1332756A3 (de) | Zusammensetzungen und Methoden zur Wiederherstellung einer normalen Zellprägung | |
BR9607178A (pt) | Antagonista de peptìdeo de hormÈnio estimulando alfa -melanócitos, processos para a inibição da atividade de hormÈnio estimulando alfa-melanócitos em um tecido ou célula que responde a hormÈnio estimulando alfa -melanócitos, para o clareamento da complexação de um animal e para o tratamento de melanoma maligno, composição farmacêutica, e, kit | |
LEVIN | A specific skin lesion in gargoylism | |
TR199801359T2 (xx) | H�cre b�y�mesini engellemek i�in kalsiyum kanal blokeri olan terkipler | |
Cole | Chronic roentgen-ray dermatoses as seen in the professional man | |
Mohammed et al. | Histopathological study of malignant melanoma in highlanders | |
Walker et al. | Nasolabial flap reconstruction for carcinoma of the lower lip: An eleven year follow-up study | |
Barthelmes et al. | An audit of the management of emergency surgical admissions in Wales: are we keeping pace with the trend? | |
WO2004019875A3 (en) | Non-invasive methods to identify agents for treating pain | |
Tsao et al. | Governance of Cutaneous Photocarcinogenesis by Chronic UVA-Exposed Dermal Fibroblasts | |
Brolsma | Precancerous dermatoses | |
Haug | Issues and controversies in the management of cleft palate: Nguyen PN, Sullivan PK. Clin Plast Surg 20: 671, 1993 | |
Ebert | CHICAGO DERMATOLOGICAL SOCIETY |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |