DE69719673T2 - D-pentofuranose-derivate und verfahren zu ihrer herstellung - Google Patents

D-pentofuranose-derivate und verfahren zu ihrer herstellung

Info

Publication number
DE69719673T2
DE69719673T2 DE69719673T DE69719673T DE69719673T2 DE 69719673 T2 DE69719673 T2 DE 69719673T2 DE 69719673 T DE69719673 T DE 69719673T DE 69719673 T DE69719673 T DE 69719673T DE 69719673 T2 DE69719673 T2 DE 69719673T2
Authority
DE
Germany
Prior art keywords
group
compound
formula
lower alkyl
sugar moiety
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69719673T
Other languages
English (en)
Other versions
DE69719673D1 (de
Inventor
Makoto Nomura
Hideki Kazuno
Tsutomu Sato
Masato Washinosu
Motoaki Tanaka
Akira Matsuda
Tetsuji Asao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Taiho Pharmaceutical Co Ltd
Original Assignee
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co Ltd filed Critical Taiho Pharmaceutical Co Ltd
Publication of DE69719673D1 publication Critical patent/DE69719673D1/de
Application granted granted Critical
Publication of DE69719673T2 publication Critical patent/DE69719673T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/08—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
    • C07H9/04—Cyclic acetals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69719673T 1996-05-16 1997-04-24 D-pentofuranose-derivate und verfahren zu ihrer herstellung Expired - Lifetime DE69719673T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP12137296 1996-05-16
PCT/JP1997/001427 WO1997043295A1 (fr) 1996-05-16 1997-04-24 Derives de d-pentofuranose et leur procede de preparation

Publications (2)

Publication Number Publication Date
DE69719673D1 DE69719673D1 (de) 2003-04-17
DE69719673T2 true DE69719673T2 (de) 2003-12-18

Family

ID=14809610

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69719673T Expired - Lifetime DE69719673T2 (de) 1996-05-16 1997-04-24 D-pentofuranose-derivate und verfahren zu ihrer herstellung

Country Status (10)

Country Link
US (1) US5880294A (de)
EP (1) EP0842942B1 (de)
JP (1) JP3046359B2 (de)
KR (1) KR100247734B1 (de)
AT (1) ATE234318T1 (de)
AU (1) AU693741B2 (de)
CA (1) CA2226363C (de)
DE (1) DE69719673T2 (de)
ES (1) ES2195136T3 (de)
WO (1) WO1997043295A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005011709A1 (en) * 2003-02-19 2005-02-10 Yale University Anti-viral nucleoside analogs and methods for treating viral infections, especially hiv infections
MY159745A (en) * 2008-11-17 2017-01-31 Anadys Pharmaceuticals Inc Method of preparing deoxyribofuranose compounds
EP2580218B1 (de) 2010-06-11 2015-02-25 Rhodes Technologies Verfahren zur n-dealkylierung von tertiären aminen
US9556216B2 (en) 2012-08-31 2017-01-31 Novartis Ag 2′-Ethynyl nucleoside derivatives for treatment of viral infections

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3480613A (en) * 1967-07-03 1969-11-25 Merck & Co Inc 2-c or 3-c-alkylribofuranosyl - 1-substituted compounds and the nucleosides thereof
JPH0753586A (ja) * 1993-08-23 1995-02-28 Sankyo Co Ltd ピリミジンヌクレオシド誘導体の製法

Also Published As

Publication number Publication date
AU2405997A (en) 1997-12-05
JP3046359B2 (ja) 2000-05-29
AU693741B2 (en) 1998-07-02
CA2226363A1 (en) 1997-11-20
DE69719673D1 (de) 2003-04-17
KR19990028434A (ko) 1999-04-15
EP0842942B1 (de) 2003-03-12
ES2195136T3 (es) 2003-12-01
US5880294A (en) 1999-03-09
ATE234318T1 (de) 2003-03-15
KR100247734B1 (ko) 2000-03-15
EP0842942A1 (de) 1998-05-20
WO1997043295A1 (fr) 1997-11-20
EP0842942A4 (de) 1999-01-13
CA2226363C (en) 2001-03-13

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Legal Events

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8364 No opposition during term of opposition