DE69711910D1 - Adenosine deaminase inhibitoren - Google Patents

Adenosine deaminase inhibitoren

Info

Publication number
DE69711910D1
DE69711910D1 DE69711910T DE69711910T DE69711910D1 DE 69711910 D1 DE69711910 D1 DE 69711910D1 DE 69711910 T DE69711910 T DE 69711910T DE 69711910 T DE69711910 T DE 69711910T DE 69711910 D1 DE69711910 D1 DE 69711910D1
Authority
DE
Germany
Prior art keywords
adenosine deaminase
range
enzyme
ada
inhibit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69711910T
Other languages
English (en)
Inventor
Elie Abushanab
V Pragnacharyulu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhode Island Board of Education
Original Assignee
Rhode Island Board of Education
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhode Island Board of Education filed Critical Rhode Island Board of Education
Application granted granted Critical
Publication of DE69711910D1 publication Critical patent/DE69711910D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DE69711910T 1996-07-15 1997-07-15 Adenosine deaminase inhibitoren Expired - Lifetime DE69711910D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/680,413 US5703084A (en) 1996-07-15 1996-07-15 Adenosine deaminase inhibitors
PCT/US1997/012754 WO1998002166A1 (en) 1996-07-15 1997-07-15 Adenosine deaminase inhibitors

Publications (1)

Publication Number Publication Date
DE69711910D1 true DE69711910D1 (de) 2002-05-16

Family

ID=24731008

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69711910T Expired - Lifetime DE69711910D1 (de) 1996-07-15 1997-07-15 Adenosine deaminase inhibitoren

Country Status (8)

Country Link
US (1) US5703084A (de)
EP (1) EP0936911B1 (de)
JP (1) JP2000516578A (de)
CN (1) CN1227489A (de)
AT (1) ATE215823T1 (de)
CA (1) CA2261591A1 (de)
DE (1) DE69711910D1 (de)
WO (1) WO1998002166A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2243220C2 (ru) * 1998-07-23 2004-12-27 Фудзисава Фармасьютикал Ко., Лтд. Имидазольные соединения, способ их получения, способ ингибирования аденозиндезаминазы и фармацевтическая композиция на их основе
EP1159263A1 (de) * 1999-02-26 2001-12-05 Merck & Co., Inc. Sulfonamid-verbindungen und anwendungen davon
AUPP921299A0 (en) * 1999-03-15 1999-04-15 Fujisawa Pharmaceutical Co., Ltd. New heterocyclic compounds
US6103702A (en) * 1999-05-24 2000-08-15 Board Of Trustees Of The University Of Illinois Use of adenosine deaminase inhibitors to treat systemic inflammatory response syndrome
AUPQ515700A0 (en) * 2000-01-19 2000-02-10 Fujisawa Pharmaceutical Co., Ltd. Imidazole compounds
US20020086835A1 (en) * 2000-05-22 2002-07-04 Law William R. Use of adenosine deaminase inhibitors to treat systemic inflammatory response syndrome
CN100352823C (zh) * 2005-08-19 2007-12-05 浙江车头制药有限公司 一种腺嘌呤衍生物的制备方法
US20100261666A1 (en) * 2009-04-14 2010-10-14 The Board Of Trustees Of The University Of Illinois Compositions and methods for the treatment of myocardial dysfunction associated with sirs or sepsis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5284837A (en) * 1988-05-06 1994-02-08 Medivir Ab Derivatives of purine, process for their preparation and a pharmaceutical preparation
US5491146A (en) * 1993-01-14 1996-02-13 Cypros Pharmaceutical Corporation Hydroxylated erythro-hydroxynonyladenines and related analogs

Also Published As

Publication number Publication date
EP0936911B1 (de) 2002-04-10
WO1998002166A1 (en) 1998-01-22
ATE215823T1 (de) 2002-04-15
EP0936911A1 (de) 1999-08-25
US5703084A (en) 1997-12-30
JP2000516578A (ja) 2000-12-12
EP0936911A4 (de) 1999-10-06
CA2261591A1 (en) 1998-01-22
CN1227489A (zh) 1999-09-01

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Legal Events

Date Code Title Description
8332 No legal effect for de