DE69711843D1 - Wasserlösliches Extrakt von Asiaticosid und Madecanoside von Centella asiatica und Verfahren zur Isolierung davon - Google Patents

Wasserlösliches Extrakt von Asiaticosid und Madecanoside von Centella asiatica und Verfahren zur Isolierung davon

Info

Publication number
DE69711843D1
DE69711843D1 DE69711843T DE69711843T DE69711843D1 DE 69711843 D1 DE69711843 D1 DE 69711843D1 DE 69711843 T DE69711843 T DE 69711843T DE 69711843 T DE69711843 T DE 69711843T DE 69711843 D1 DE69711843 D1 DE 69711843D1
Authority
DE
Germany
Prior art keywords
madecanoside
asiaticoside
isolation
water soluble
soluble extract
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69711843T
Other languages
English (en)
Other versions
DE69711843T2 (de
Inventor
Kweon Kim
Sung-Ki Seo
Jin-Kyu Park
Seung-Yong Lee
Byeong-Ryong Hwang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dong Kook Pharmaceutical Co Ltd
Original Assignee
Dong Kook Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dong Kook Pharmaceutical Co Ltd filed Critical Dong Kook Pharmaceutical Co Ltd
Publication of DE69711843D1 publication Critical patent/DE69711843D1/de
Application granted granted Critical
Publication of DE69711843T2 publication Critical patent/DE69711843T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/08—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
DE69711843T 1997-03-24 1997-08-19 Wasserlösliches Extrakt von Asiaticosid und Madecanoside von Centella asiatica und Verfahren zur Isolierung davon Expired - Fee Related DE69711843T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019970010114A KR100228873B1 (ko) 1997-03-24 1997-03-24 센텔라아시아티카에서 분리한 아시아티코사이드와 마테카소 사이드의 수용성 추출물을 함유한 간세포 및 항간섬유화 치료제

Publications (2)

Publication Number Publication Date
DE69711843D1 true DE69711843D1 (de) 2002-05-16
DE69711843T2 DE69711843T2 (de) 2002-08-08

Family

ID=19500603

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69711843T Expired - Fee Related DE69711843T2 (de) 1997-03-24 1997-08-19 Wasserlösliches Extrakt von Asiaticosid und Madecanoside von Centella asiatica und Verfahren zur Isolierung davon

Country Status (5)

Country Link
US (1) US6417349B1 (de)
EP (1) EP0867447B1 (de)
JP (1) JPH10279590A (de)
KR (1) KR100228873B1 (de)
DE (1) DE69711843T2 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100530278B1 (ko) * 1997-02-28 2006-04-06 동국제약 주식회사 아시아트산 유도체를 유효성분으로 하는 간 보호 및치료제
IL143318A0 (en) 2001-05-23 2002-04-21 Herbal Synthesis Corp Herbal compositions for the treatment of mucosal lesions
DE20109044U1 (de) * 2001-05-30 2001-08-09 Weber & Weber Gmbh & Co Kg Pharmazeutische Zubereitung
JP2004002335A (ja) * 2002-03-28 2004-01-08 Ortho Corporation 不定愁訴症状改善剤及び食品とその組成物
CA2496790C (en) * 2002-08-23 2012-11-20 The Research Foundation Of State University Of New York Plant extracts stimulating nitric oxide production and their use in the treatment of inflammation and related diseases
FR2848117B1 (fr) * 2002-12-10 2006-08-04 Roche Consumer Health Ltd Procede de preparation d'un extrait de centella asiatica riche en madecassoside et en terminoloside
WO2006012015A2 (en) * 2004-06-29 2006-02-02 Oregon Health And Science University Methods and compositions for nerve regeneration
CN1595147B (zh) * 2004-07-02 2010-04-28 桂林三金药业股份有限公司 一种三金制剂中羟基积雪草苷和/或积雪草苷含量的检测方法
US20070010459A1 (en) * 2005-01-14 2007-01-11 Ying Liu Application of asiatic acid and its derivatives to treat pulmonary fibrosis
US20070071840A1 (en) * 2005-09-27 2007-03-29 Sridevi Dhanaraj Method for treatment of cartilage disorders with centella extract
TWI361074B (en) * 2005-12-22 2012-04-01 Dev Center Biotechnology Plant extracts for enhancing healing of wounds,and the preparation process and use thereof
EP1925310B1 (de) 2006-11-24 2015-03-25 Development Center For Biotechnology Pflanzenextrakte aus Plectranthus und Centella zur Behandlung von Hautkrankeiten und zur Beschleunigung der Wundheilung bei Diabetikern
KR101183045B1 (ko) * 2007-02-12 2012-09-20 인두스 바이오텍 프라이빗 리미티드 선택적 세로토닌 재흡수 억제를 위한 조성물 및 그 제조 방법
US8449924B2 (en) * 2007-08-29 2013-05-28 Development Center For Biotechnology Process for the preparation of plant extracts for treating skin disorders and enhancing healing of wounds
WO2009089365A2 (en) * 2008-01-11 2009-07-16 Shanghai Institute Of Pharmaceutical Industry (Sipi) Therapeutic formulations based on asiatic acid and selected salts thereof
US20110236324A1 (en) * 2010-03-23 2011-09-29 Namita Deo Plant extracts, compositions containing same, and uses thereof
BR112012031095B1 (pt) * 2010-06-10 2020-05-05 Indus Biotech Private Ltd método para preparação de uma composição de asiaticoside altamente pura a partir de centella asiatica de um método para seu uso
FR2964570A1 (fr) * 2010-09-09 2012-03-16 Burgundy Procede de preparation d'un extrait de centella asiatica
PL2708596T3 (pl) 2012-09-14 2017-04-28 Casen Recordati, S.L. Hodowle komórek roślinnych z rodzaju Centella, sposób ich wytwarzania i ich zastosowanie
PL2708232T3 (pl) 2012-09-14 2017-04-28 Casen Recordati, S.L. Kompozycja zawierająca hodowlę komórek roślinnych w zawiesinie z Cantella asiatica
KR102362362B1 (ko) 2016-07-17 2022-02-14 원니스 바이오테크 컴퍼니 리미티드 상처 치유를 증진시키기 위한 국소 제형
WO2023036404A1 (en) 2021-09-07 2023-03-16 Symrise Ag Taste balancing botanical compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR870001458A (ko) 1985-07-01 1987-03-13 오수만 익차형 복갑식 수도미터
JPH0760544B2 (ja) 1985-07-17 1995-06-28 ソニー株式会社 記録再生装置のテ−プガイド機構
US5166139A (en) * 1987-02-26 1992-11-24 Indena, S.P.A. Complexes of saponins and their aglycons with phospholipids and pharmaceutical and cosmetic compositions containing them
JP2841080B2 (ja) 1989-07-22 1998-12-24 株式会社新川 版台固定構造
GB2309695B (en) * 1994-12-03 1998-12-02 Dong Kook Pharm Co Ltd Asiatic acid derivative, it's manufacturing method and dermatological agent containing it

Also Published As

Publication number Publication date
JPH10279590A (ja) 1998-10-20
EP0867447A1 (de) 1998-09-30
US6417349B1 (en) 2002-07-09
KR100228873B1 (ko) 1999-11-01
DE69711843T2 (de) 2002-08-08
KR19980074333A (ko) 1998-11-05
EP0867447B1 (de) 2002-04-10

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee