DE69707080T2 - Pyrrolidinonderivate und ihre Verwendung als antipsychotische Arzneimittel - Google Patents

Pyrrolidinonderivate und ihre Verwendung als antipsychotische Arzneimittel

Info

Publication number
DE69707080T2
DE69707080T2 DE69707080T DE69707080T DE69707080T2 DE 69707080 T2 DE69707080 T2 DE 69707080T2 DE 69707080 T DE69707080 T DE 69707080T DE 69707080 T DE69707080 T DE 69707080T DE 69707080 T2 DE69707080 T2 DE 69707080T2
Authority
DE
Germany
Prior art keywords
antipsychotic drugs
pyrrolidinone derivatives
pyrrolidinone
derivatives
antipsychotic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69707080T
Other languages
English (en)
Other versions
DE69707080D1 (de
Inventor
Naruyoshi Mita
Hiroshi Nagase
Hajime Iizuka
Takahisa Oguchi
Kazuya Sakai
Kazutoshi Horikomi
Takaichi Miwa
Shinji Takahashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Application granted granted Critical
Publication of DE69707080D1 publication Critical patent/DE69707080D1/de
Publication of DE69707080T2 publication Critical patent/DE69707080T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE69707080T 1996-11-01 1997-11-03 Pyrrolidinonderivate und ihre Verwendung als antipsychotische Arzneimittel Expired - Fee Related DE69707080T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP29158796 1996-11-01

Publications (2)

Publication Number Publication Date
DE69707080D1 DE69707080D1 (de) 2001-11-08
DE69707080T2 true DE69707080T2 (de) 2002-05-02

Family

ID=17770878

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69707080T Expired - Fee Related DE69707080T2 (de) 1996-11-01 1997-11-03 Pyrrolidinonderivate und ihre Verwendung als antipsychotische Arzneimittel

Country Status (4)

Country Link
US (1) US5969138A (de)
EP (1) EP0839805B1 (de)
DE (1) DE69707080T2 (de)
ES (1) ES2163717T3 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10004572A1 (de) * 2000-02-02 2001-08-09 Boehringer Ingelheim Pharma Neue positive allosterische AMPA-Rezeptor Modulatoren (PAARM), Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
GB2463283A (en) * 2008-09-08 2010-03-10 Cambridge Lab 3,11b-cis-dihydrotetrabenazine for use in treating asthma
GB2463451A (en) 2008-09-08 2010-03-17 Cambridge Lab 3, 11b cis-dihydrotetrabenazine compounds for use in the treatment of dementia
WO2021236879A1 (en) 2020-05-20 2021-11-25 The Board Of Trustees Of The University Of Illinois Method for treating lysosomal storage diseases with histatin peptides

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2537133A1 (fr) * 1982-12-07 1984-06-08 Rhone Poulenc Sante Nouveaux derives de la (piperazinyl-1)-5 pyrrolidine, leur preparation et les medicaments qui les contiennent
DE3336024A1 (de) * 1983-10-04 1985-04-18 Boehringer Ingelheim KG, 6507 Ingelheim 4-amino-l-benzyl-pyrrolidinone und ihre saeureadditionssalze, verfahren zu ihrer herstellung und arzneimittel
JP3786984B2 (ja) * 1994-01-27 2006-06-21 シエーリング アクチエンゲゼルシャフト ピペラジン誘導体
US5538985A (en) * 1994-01-27 1996-07-23 Mitsui Toatsu Chemicals, Inc. Pyrrolidinone derivatives
JPH0940667A (ja) * 1995-07-26 1997-02-10 Mitsui Toatsu Chem Inc ピロリジノン誘導体およびその光学分割方法

Also Published As

Publication number Publication date
EP0839805A1 (de) 1998-05-06
US5969138A (en) 1999-10-19
EP0839805B1 (de) 2001-10-04
ES2163717T3 (es) 2002-02-01
DE69707080D1 (de) 2001-11-08

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: BAYER SCHERING PHARMA AG, 13353 BERLIN, DE

8327 Change in the person/name/address of the patent owner

Owner name: BAYER SCHERING PHARMA AKIENGESELLSCHAFT, 13353, DE

8339 Ceased/non-payment of the annual fee