DE69412083D1 - Phenylpyrrolderivate und ihre verwendung als antipsychotika - Google Patents

Phenylpyrrolderivate und ihre verwendung als antipsychotika

Info

Publication number
DE69412083D1
DE69412083D1 DE69412083T DE69412083T DE69412083D1 DE 69412083 D1 DE69412083 D1 DE 69412083D1 DE 69412083 T DE69412083 T DE 69412083T DE 69412083 T DE69412083 T DE 69412083T DE 69412083 D1 DE69412083 D1 DE 69412083D1
Authority
DE
Germany
Prior art keywords
antipesychotics
phenylpyrrol
derivatives
phenylpyrrol derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69412083T
Other languages
English (en)
Inventor
Michael Stewart Hadley
Christopher N Johnson
Geoffrey Stemp
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Original Assignee
SmithKline Beecham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd
Application granted granted Critical
Publication of DE69412083D1 publication Critical patent/DE69412083D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/02—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing not further condensed quinolizine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69412083T 1993-04-08 1994-03-29 Phenylpyrrolderivate und ihre verwendung als antipsychotika Expired - Lifetime DE69412083D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939307400A GB9307400D0 (en) 1993-04-08 1993-04-08 Compounds
PCT/EP1994/000992 WO1994024129A1 (en) 1993-04-08 1994-03-29 Phenylpyrrole derivatives and their use as antipsychotic agents

Publications (1)

Publication Number Publication Date
DE69412083D1 true DE69412083D1 (de) 1998-09-03

Family

ID=10733590

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69412083T Expired - Lifetime DE69412083D1 (de) 1993-04-08 1994-03-29 Phenylpyrrolderivate und ihre verwendung als antipsychotika

Country Status (6)

Country Link
US (1) US5688790A (de)
EP (1) EP0693068B1 (de)
JP (1) JPH08508509A (de)
DE (1) DE69412083D1 (de)
GB (1) GB9307400D0 (de)
WO (1) WO1994024129A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9512129D0 (en) * 1995-06-15 1995-08-16 Smithkline Beecham Plc Compounds
GB9708805D0 (en) 1997-05-01 1997-06-25 Smithkline Beecham Plc Compounds
GB9810876D0 (en) 1998-05-20 1998-07-22 Smithkline Beecham Plc Compounds
DE69929704T2 (de) 1998-10-08 2006-07-20 Smithkline Beecham Plc, Brentford Tetrahydrobenzazepin-derivate verwendbar als dopamin-d3-rezeptor-modulatoren (antipsychotische mittel)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0036269A1 (de) * 1980-03-15 1981-09-23 Beecham Group Plc Substituierte Benzamide
CA1279645C (en) * 1986-02-27 1991-01-29 Ineke Van Wijngaarden Aryl-substituted (n-piperidinyl)methyl- and (n-piperazinyl)methylazoles having antipsychotic properties
PH23898A (en) * 1986-09-12 1989-12-18 Duphar Int Res New phenyl pyrrolidin-2-yl substituted-2-yl substituted 5-ring heterocycles having antipsycotic properties
DK443489D0 (da) * 1989-09-08 1989-09-08 Ferrosan As Substituerede urinstofforbindelser, deres fremstilling og anvendelse
US5523299A (en) * 1992-08-06 1996-06-04 Smithkline Beecham Plc 5-(2-oxyphenyl)-pyrrole derivatives as dopamine D3 receptor antagonists

Also Published As

Publication number Publication date
EP0693068B1 (de) 1998-07-29
US5688790A (en) 1997-11-18
EP0693068A1 (de) 1996-01-24
GB9307400D0 (en) 1993-06-02
WO1994024129A1 (en) 1994-10-27
JPH08508509A (ja) 1996-09-10

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Legal Events

Date Code Title Description
8332 No legal effect for de