DE69637278D1 - Methode zur herstellung von thrombin - Google Patents

Methode zur herstellung von thrombin

Info

Publication number
DE69637278D1
DE69637278D1 DE69637278T DE69637278T DE69637278D1 DE 69637278 D1 DE69637278 D1 DE 69637278D1 DE 69637278 T DE69637278 T DE 69637278T DE 69637278 T DE69637278 T DE 69637278T DE 69637278 D1 DE69637278 D1 DE 69637278D1
Authority
DE
Germany
Prior art keywords
thrombin
prothrombin
production
containing material
contacted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69637278T
Other languages
English (en)
Inventor
Adrian Malcolm Oates
Malgorzata Kupczyk
Jerry Kanellos
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CSL Ltd
Original Assignee
CSL Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CSL Ltd filed Critical CSL Ltd
Application granted granted Critical
Publication of DE69637278D1 publication Critical patent/DE69637278D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6429—Thrombin (3.4.21.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21005—Thrombin (3.4.21.5)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
DE69637278T 1995-07-24 1996-07-22 Methode zur herstellung von thrombin Expired - Lifetime DE69637278D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPN4369A AUPN436995A0 (en) 1995-07-24 1995-07-24 Method for the production of thrombin
PCT/AU1996/000457 WO1997004081A1 (en) 1995-07-24 1996-07-22 Method for the production of thrombin

Publications (1)

Publication Number Publication Date
DE69637278D1 true DE69637278D1 (de) 2007-11-15

Family

ID=3788704

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69637278T Expired - Lifetime DE69637278D1 (de) 1995-07-24 1996-07-22 Methode zur herstellung von thrombin

Country Status (14)

Country Link
US (1) US6168938B1 (de)
EP (1) EP0846166B1 (de)
JP (1) JP3810439B2 (de)
KR (1) KR19990035874A (de)
AT (1) ATE374812T1 (de)
AU (2) AUPN436995A0 (de)
CA (1) CA2227883C (de)
DE (1) DE69637278D1 (de)
DK (1) DK0846166T3 (de)
ES (1) ES2294788T3 (de)
HK (1) HK1011549A1 (de)
NZ (1) NZ312625A (de)
WO (1) WO1997004081A1 (de)
ZA (1) ZA966192B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998057678A2 (en) * 1997-06-18 1998-12-23 Cohesion Technologies, Inc. Compositions containing thrombin and microfibrillar collagen
US6274090B1 (en) * 1998-08-05 2001-08-14 Thermogenesis Corp. Apparatus and method of preparation of stable, long term thrombin from plasma and thrombin formed thereby
SE1050124A1 (sv) * 2010-02-08 2011-08-09 Linkoping Biocontrols Ab Stabil lösning

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0044343B1 (de) * 1980-01-28 1984-08-22 Baxter Travenol Laboratories, Inc. Prothrombin enthaltende therapeutische zusammensetzungen und verfahren zur herstellung enzymatisch aktiver blutgerinnungsfaktoren aus prothrombin enthaltenden blutfraktionen
DE69130990T2 (de) * 1990-02-20 1999-12-02 Baxter Int Gereinigtes, virusfreies menschliches Thrombin
DE4137996A1 (de) * 1991-11-19 1993-05-27 Behringwerke Ag Verfahren zur herstellung eines virussicheren thrombinkonzentrates
JPH07308190A (ja) * 1994-05-18 1995-11-28 Green Cross Corp:The トロンビンの製造方法

Also Published As

Publication number Publication date
AUPN436995A0 (en) 1995-08-17
CA2227883C (en) 2007-05-08
CA2227883A1 (en) 1997-02-06
WO1997004081A1 (en) 1997-02-06
ATE374812T1 (de) 2007-10-15
US6168938B1 (en) 2001-01-02
AU695396B2 (en) 1998-08-13
EP0846166A1 (de) 1998-06-10
ES2294788T3 (es) 2008-04-01
JPH11509101A (ja) 1999-08-17
EP0846166A4 (de) 2001-06-13
ZA966192B (en) 1997-03-17
KR19990035874A (ko) 1999-05-25
AU6409596A (en) 1997-02-18
EP0846166B1 (de) 2007-10-03
NZ312625A (en) 1999-01-28
DK0846166T3 (da) 2008-02-04
JP3810439B2 (ja) 2006-08-16
HK1011549A1 (en) 1999-07-16

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Legal Events

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