DE69636456D1 - In-vitro verpackung von adeno-assozierten virus dns - Google Patents

In-vitro verpackung von adeno-assozierten virus dns

Info

Publication number
DE69636456D1
DE69636456D1 DE69636456T DE69636456T DE69636456D1 DE 69636456 D1 DE69636456 D1 DE 69636456D1 DE 69636456 T DE69636456 T DE 69636456T DE 69636456 T DE69636456 T DE 69636456T DE 69636456 D1 DE69636456 D1 DE 69636456D1
Authority
DE
Germany
Prior art keywords
packaging
adeno
packaged
vitro
aav particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69636456T
Other languages
English (en)
Other versions
DE69636456T2 (de
Inventor
Xiaohuai Zhou
Nicholas Muzyczka
Sergei Zolotukhin
Tiehua Ni
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Research Foundation of State University of New York
Original Assignee
Research Foundation of State University of New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Foundation of State University of New York filed Critical Research Foundation of State University of New York
Application granted granted Critical
Publication of DE69636456D1 publication Critical patent/DE69636456D1/de
Publication of DE69636456T2 publication Critical patent/DE69636456T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69636456T 1995-06-07 1996-06-05 In-vitro verpackung von adeno-assoziierten virus dns Expired - Fee Related DE69636456T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/476,018 US5688675A (en) 1995-06-07 1995-06-07 In vitro packaging of adeno-associated virus DNA
US476018 1995-06-07
PCT/US1996/009263 WO1996040270A1 (en) 1995-06-07 1996-06-05 In vitro packaging of adeno-associated virus dna

Publications (2)

Publication Number Publication Date
DE69636456D1 true DE69636456D1 (de) 2006-09-28
DE69636456T2 DE69636456T2 (de) 2007-04-19

Family

ID=23890161

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69636456T Expired - Fee Related DE69636456T2 (de) 1995-06-07 1996-06-05 In-vitro verpackung von adeno-assoziierten virus dns

Country Status (8)

Country Link
US (1) US5688675A (de)
EP (1) EP0836484B1 (de)
JP (1) JP3944240B2 (de)
AT (1) ATE336588T1 (de)
AU (1) AU706266B2 (de)
CA (1) CA2222534A1 (de)
DE (1) DE69636456T2 (de)
WO (1) WO1996040270A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020037867A1 (en) * 1999-02-26 2002-03-28 James M. Wilson Method for recombinant adeno-associated virus-directed gene therapy
US20050281786A1 (en) * 2004-06-18 2005-12-22 David Poulsen AAV mediated gene delivery to cochlear cells
WO2012144446A1 (ja) * 2011-04-18 2012-10-26 独立行政法人国立精神・神経医療研究センター 薬剤送達粒子及びその製造方法
ES2948849T3 (es) * 2016-11-04 2023-09-20 Takeda Pharmaceuticals Co Métodos de purificación de virus adenoasociado

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4797368A (en) * 1985-03-15 1989-01-10 The United States Of America As Represented By The Department Of Health And Human Services Adeno-associated virus as eukaryotic expression vector
US5139941A (en) * 1985-10-31 1992-08-18 University Of Florida Research Foundation, Inc. AAV transduction vectors

Also Published As

Publication number Publication date
EP0836484A4 (de) 2002-03-27
AU6094796A (en) 1996-12-30
JP3944240B2 (ja) 2007-07-11
DE69636456T2 (de) 2007-04-19
US5688675A (en) 1997-11-18
EP0836484A1 (de) 1998-04-22
EP0836484B1 (de) 2006-08-16
ATE336588T1 (de) 2006-09-15
JPH11512923A (ja) 1999-11-09
WO1996040270A1 (en) 1996-12-19
AU706266B2 (en) 1999-06-10
CA2222534A1 (en) 1996-12-19

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee