DE69636048D1 - Piperazin- und Homopiperazinderivate zur Hemmung der Zellenadhäsion und Zelleninfiltration - Google Patents

Piperazin- und Homopiperazinderivate zur Hemmung der Zellenadhäsion und Zelleninfiltration

Info

Publication number
DE69636048D1
DE69636048D1 DE69636048T DE69636048T DE69636048D1 DE 69636048 D1 DE69636048 D1 DE 69636048D1 DE 69636048 T DE69636048 T DE 69636048T DE 69636048 T DE69636048 T DE 69636048T DE 69636048 D1 DE69636048 D1 DE 69636048D1
Authority
DE
Germany
Prior art keywords
piperazine
cell adhesion
cell
agent
inhibiting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69636048T
Other languages
English (en)
Other versions
DE69636048T2 (de
Inventor
Hiroshi Nakao
Michihisa Umetani
Makoto Suda
Takao Nagoya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kowa Co Ltd
Original Assignee
Kowa Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kowa Co Ltd filed Critical Kowa Co Ltd
Publication of DE69636048D1 publication Critical patent/DE69636048D1/de
Application granted granted Critical
Publication of DE69636048T2 publication Critical patent/DE69636048T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Urology & Nephrology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE69636048T 1995-11-20 1996-11-18 Inhibitoren der zellenadhäsion und zelleninfiltration Expired - Fee Related DE69636048T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP30152695A JP3808921B2 (ja) 1995-11-20 1995-11-20 細胞接着阻害剤
JP30152695 1995-11-20

Publications (2)

Publication Number Publication Date
DE69636048D1 true DE69636048D1 (de) 2006-05-24
DE69636048T2 DE69636048T2 (de) 2006-08-31

Family

ID=17897999

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69636048T Expired - Fee Related DE69636048T2 (de) 1995-11-20 1996-11-18 Inhibitoren der zellenadhäsion und zelleninfiltration

Country Status (5)

Country Link
US (1) US5723465A (de)
EP (1) EP0774257B1 (de)
JP (1) JP3808921B2 (de)
AT (1) ATE323492T1 (de)
DE (1) DE69636048T2 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE372320T1 (de) * 1998-02-19 2007-09-15 Kowa Co Cyclische amidderivate
US6432957B1 (en) * 2001-06-29 2002-08-13 Kowa Co., Ltd. Piperazine derivative
US6632810B2 (en) 2001-06-29 2003-10-14 Kowa Co., Ltd. Cyclic diamine compound with condensed-ring groups
US6552188B2 (en) 2001-06-29 2003-04-22 Kowa Co., Ltd. Unsymmetrical cyclic diamine compound
US6509329B1 (en) * 2001-06-29 2003-01-21 Kowa Co., Ltd. Cyclic diamine compound with 6-membered ring groups
US6472386B1 (en) * 2001-06-29 2002-10-29 Kowa Co., Ltd. Cyclic diamine compound with 5-membered ring groups
US6867221B2 (en) * 2001-08-30 2005-03-15 Kowa Co., Ltd. Cyclic amine compounds and pharmaceutical composition containing the same
US6605620B1 (en) 2001-08-30 2003-08-12 Kowa Co., Ltd. Cyclic amine compounds and pharmaceutical composition containing the same
US6395753B1 (en) 2001-08-30 2002-05-28 Kowa Co., Ltd. Cyclic amine compounds and pharmaceutical composition containing the same
MY134200A (en) * 2002-04-12 2007-11-30 Kowa Co Method for treating cancer
AU2003243010A1 (en) * 2002-06-28 2004-01-19 Kowa Co., Ltd. Erythropoietin production potentiator
WO2004032933A1 (ja) * 2002-10-11 2004-04-22 Kowa Co., Ltd. 癌の処置方法
WO2004032931A1 (ja) * 2002-10-11 2004-04-22 Kowa Co., Ltd. 癌の処置方法
WO2004032930A1 (ja) * 2002-10-11 2004-04-22 Kowa Co., Ltd. 癌の処置方法
JP6026413B2 (ja) * 2011-06-23 2016-11-16 学校法人自治医科大学 プロテアソーム阻害剤

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5732255A (en) * 1980-08-05 1982-02-20 Kowa Co Trimethoxyphenyl derivative
JP2722250B2 (ja) * 1989-05-30 1998-03-04 興和株式会社 新規なジアミン化合物及びこれを含有する脳機能障害改善剤

Also Published As

Publication number Publication date
ATE323492T1 (de) 2006-05-15
EP0774257A2 (de) 1997-05-21
US5723465A (en) 1998-03-03
EP0774257B1 (de) 2006-04-19
JPH09143075A (ja) 1997-06-03
JP3808921B2 (ja) 2006-08-16
DE69636048T2 (de) 2006-08-31
EP0774257A3 (de) 1997-08-27

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee