JPS5732255A - Trimethoxyphenyl derivative - Google Patents
Trimethoxyphenyl derivativeInfo
- Publication number
- JPS5732255A JPS5732255A JP10743980A JP10743980A JPS5732255A JP S5732255 A JPS5732255 A JP S5732255A JP 10743980 A JP10743980 A JP 10743980A JP 10743980 A JP10743980 A JP 10743980A JP S5732255 A JPS5732255 A JP S5732255A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound shown
- trimethoxyphenyl
- derivative
- actions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
NEW MATERIAL:A compound shown by the formula I [A is CH=CH-CO, CH= CH-CH2, group shown by the formula II, COO-(CH3)2; R1 and R2 are alkyl, form ethylene or propylene; R is pyrrolidinoalkyl-carbonyl, pyrrolidinocarbonylalkyl, alkoxycarbonylalkyl, trimethoxycinnamyl, etc.].
EXAMPLE: N,N'-Dimethyl-N-(1-pyrrolidinocarbonylmethyl)-N'-(3,4,5-trimethoxycinnamoyl)-ethylenediamine.
USE: Having vasodilating actions, antiarrhythmic actions, etc., useful as a circulatory organ type drug.
PROCESS: A compound shown by the formula III (X is halogen) is reacted with a compound shown by the formula IV in a proper solvent (e.g., benzene, THF, etc.) in the presence of a deoxidizer, e.g., triethylamine, K2CO3, etc., to give a compound shown by the formula I.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10743980A JPS5732255A (en) | 1980-08-05 | 1980-08-05 | Trimethoxyphenyl derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10743980A JPS5732255A (en) | 1980-08-05 | 1980-08-05 | Trimethoxyphenyl derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5732255A true JPS5732255A (en) | 1982-02-20 |
JPS6323986B2 JPS6323986B2 (en) | 1988-05-18 |
Family
ID=14459169
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP10743980A Granted JPS5732255A (en) | 1980-08-05 | 1980-08-05 | Trimethoxyphenyl derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5732255A (en) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2522325A1 (en) * | 1982-02-26 | 1983-09-02 | Delalande Sa | NOVEL ARYLIC DERIVATIVES OF PIPERAZINE, HOMOPIPERAZINE AND N, N'-DIALKYL DIAMINO-1,2 ETHANE, PROCESS FOR PREPARING THEM AND THEIR THERAPEUTIC USE |
EP0136945A2 (en) * | 1983-09-30 | 1985-04-10 | Delalande S.A. | Cinnamoyl compounds, process for their preparation and their therapeutical use |
US4780560A (en) * | 1986-03-05 | 1988-10-25 | Terumo Corporation | Nitrate derivatives and vasodilators containing the same |
WO1992002487A1 (en) * | 1989-05-30 | 1992-02-20 | Kowa Co., Ltd. | New diamine compound and brain protecting agent containing the same |
EP0774257A3 (en) * | 1995-11-20 | 1997-08-27 | Kowa Co | Use of piperazine and homopiperazine compounds for the inhibition of cellular adhesion and infiltration |
WO1998007702A1 (en) * | 1996-08-23 | 1998-02-26 | Kowa Co., Ltd. | Diamide compounds and drugs containing the same |
-
1980
- 1980-08-05 JP JP10743980A patent/JPS5732255A/en active Granted
Cited By (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2522325A1 (en) * | 1982-02-26 | 1983-09-02 | Delalande Sa | NOVEL ARYLIC DERIVATIVES OF PIPERAZINE, HOMOPIPERAZINE AND N, N'-DIALKYL DIAMINO-1,2 ETHANE, PROCESS FOR PREPARING THEM AND THEIR THERAPEUTIC USE |
JPS58159484A (en) * | 1982-02-26 | 1983-09-21 | ドウラランドウ・ソシエテ・アノニム | Novel piperazine derivative and manufacture |
JPH0518830B2 (en) * | 1982-02-26 | 1993-03-15 | Delalande Sa | |
EP0136945A2 (en) * | 1983-09-30 | 1985-04-10 | Delalande S.A. | Cinnamoyl compounds, process for their preparation and their therapeutical use |
US4780560A (en) * | 1986-03-05 | 1988-10-25 | Terumo Corporation | Nitrate derivatives and vasodilators containing the same |
WO1992002487A1 (en) * | 1989-05-30 | 1992-02-20 | Kowa Co., Ltd. | New diamine compound and brain protecting agent containing the same |
US5389630A (en) * | 1989-05-30 | 1995-02-14 | Kowa Co., Ltd. | Diamine compound and brain protecting agent containing the same |
EP0774257A3 (en) * | 1995-11-20 | 1997-08-27 | Kowa Co | Use of piperazine and homopiperazine compounds for the inhibition of cellular adhesion and infiltration |
WO1998007702A1 (en) * | 1996-08-23 | 1998-02-26 | Kowa Co., Ltd. | Diamide compounds and drugs containing the same |
US6340682B1 (en) * | 1996-08-23 | 2002-01-22 | Kowa Co., Ltd. | Diamide compound and drugs containing the same |
US6828316B2 (en) | 1996-08-23 | 2004-12-07 | Kowa Co., Ltd. | Diamide compound and medicine containing the same |
EP0926138A4 (en) * | 1996-08-23 | 2006-04-12 | Kowa Co | Diamide compounds and drugs containing the same |
Also Published As
Publication number | Publication date |
---|---|
JPS6323986B2 (en) | 1988-05-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JPS5432460A (en) | Cycloalkylidenemethylphenylacetic acid derivative and their preparation | |
JPS5732255A (en) | Trimethoxyphenyl derivative | |
JPS5271444A (en) | Synthesis of phenyl-onn-azoxycyanides | |
JPS5731671A (en) | Preparation of homopiperazine derivative | |
JPS5424882A (en) | Novel heterocyclic compounds and their preparation | |
JPS5346989A (en) | Novel dibenzo(b,f)thiepin derivatives and their preparation | |
JPS5210266A (en) | Pyrrolidine series herbicides | |
JPS57102957A (en) | Dye-dissolving aid | |
JPS5414956A (en) | Novel 3-amino-4-homoisotwistan derivative | |
JPS554329A (en) | Imidazolonecarboxamide derivative and its preparation | |
JPS52151191A (en) | Novel antibiotics neoviridogriseins and their preparation | |
JPS52122358A (en) | Novel methano-anthracene derivatives | |
JPS55104274A (en) | Isoxazolin-3-one derivative and its preparation | |
JPS5732260A (en) | Mercaptofatty acid derivative and its preparation | |
JPS5555168A (en) | Novel 4-carboxy-2-phenyl-1-phthalazone derivative | |
JPS5368751A (en) | Thiocyclopentanol derivatives and their preparation | |
JPS52139075A (en) | Novel morpholine derivatives | |
JPS5629578A (en) | Novel cyclic urethane compound and its preparation | |
JPS5527142A (en) | Novel 1-phthalazone derivative | |
JPS5212161A (en) | Succinimide compounds and fungicides for agricultural and gardening us e | |
JPS5271478A (en) | Synthesis of novel derivatives of kanamycin b | |
JPS5651461A (en) | Novel 3-phenyl-4-quinazolone derivative | |
JPS523031A (en) | Novel tyrosinol derivatives | |
JPS52131590A (en) | Bis-trimethoxybenzylpiperazino-alkanes | |
JPS5283706A (en) | Novel propargyl alcohol derivatives and preparation thereof |