DE69635301D1 - Verminderung von adhäsionen durch gesteuerte verabreichung von aktivsauerstoffinhibitoren - Google Patents
Verminderung von adhäsionen durch gesteuerte verabreichung von aktivsauerstoffinhibitorenInfo
- Publication number
- DE69635301D1 DE69635301D1 DE69635301T DE69635301T DE69635301D1 DE 69635301 D1 DE69635301 D1 DE 69635301D1 DE 69635301 T DE69635301 T DE 69635301T DE 69635301 T DE69635301 T DE 69635301T DE 69635301 D1 DE69635301 D1 DE 69635301D1
- Authority
- DE
- Germany
- Prior art keywords
- adhesions
- inhibitors
- active
- surfactures
- reduction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/44—Oxidoreductases (1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/44—Oxidoreductases (1)
- A61K38/446—Superoxide dismutase (1.15)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US410219 | 1989-09-21 | ||
US41021995A | 1995-03-24 | 1995-03-24 | |
PCT/US1996/003813 WO1996029987A1 (en) | 1995-03-24 | 1996-03-20 | Reduction of adhesions using controlled delivery of active oxygen inhibitors |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69635301D1 true DE69635301D1 (de) | 2006-03-02 |
DE69635301T2 DE69635301T2 (de) | 2006-07-20 |
Family
ID=23623783
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69635301T Expired - Lifetime DE69635301T2 (de) | 1995-03-24 | 1996-03-20 | Verminderung von adhäsionen durch gesteuerte verabreichung von aktivsauerstoffinhibitoren |
Country Status (8)
Country | Link |
---|---|
US (2) | US5785993A (de) |
EP (1) | EP0814774B1 (de) |
JP (1) | JP3145409B2 (de) |
AT (1) | ATE306903T1 (de) |
AU (1) | AU704222B2 (de) |
CA (1) | CA2215317C (de) |
DE (1) | DE69635301T2 (de) |
WO (1) | WO1996029987A1 (de) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3145409B2 (ja) * | 1995-03-24 | 2001-03-12 | フォーカル, インコーポレイテッド | 活性酸素阻害剤の制御送達を用いる癒着の低減 |
US5899917A (en) * | 1997-03-12 | 1999-05-04 | Cardiosynopsis, Inc. | Method for forming a stent in situ |
US6123667A (en) * | 1997-03-20 | 2000-09-26 | Focal, Inc. | Retracting tissue using photoadhering adhesive |
EP0887076A3 (de) * | 1997-05-07 | 1999-03-31 | Saturnus A.G. | Verhinderung von Gewebeverklebung und ein dafür vorgesehenes endoskopisches System zum Aufblasen einer Körperhöhle |
AU1520699A (en) * | 1997-11-07 | 1999-05-31 | Johns Hopkins University, The | Methods for treatment of disorders of cardiac contractility |
US6627663B2 (en) | 1998-08-03 | 2003-09-30 | W. Jerry Easterling | Noninvasive method for treating hemangiomas through transdermal delivery of calcium channel blocker agents and medicament for use in such method |
US6525100B1 (en) | 1998-08-03 | 2003-02-25 | W. Jerry Easterling | Composition and method for treating peyronie's disease and related fibrotic tissue disorders |
ATE378055T1 (de) * | 1998-08-03 | 2007-11-15 | Ronald E Wheeler | Prostata- formulierung |
US6031005A (en) * | 1998-08-03 | 2000-02-29 | Easterling; W. Jerry | Composition and method for treating Peyronie's disease and related connective tissue disorders |
US20080114092A1 (en) * | 1998-12-04 | 2008-05-15 | Incept Llc | Adhesion barriers applicable by minimally invasive surgery and methods of use thereof |
KR100558239B1 (ko) | 1999-12-23 | 2006-03-10 | 화이자 프로덕츠 인크. | 증가된 약물 농도를 제공하는 제약학적 조성물 |
JP2003528148A (ja) * | 2000-03-28 | 2003-09-24 | デロレンゾ、ロバート・ジェイ | 損傷に際して神経細胞中に形成される新規カルシウム損傷電流の阻害は神経細胞死を抑制する |
FI20010898A0 (fi) * | 2001-04-30 | 2001-04-30 | Ylae Herttuala Seppo | Ekstrasellulaarinen superoksididismutaasi (EC-SOD) geeniterapia restenoosoin ehkäisemiseksi |
WO2003092727A1 (en) * | 2002-04-30 | 2003-11-13 | Fit Biotech Oyj Plc | Medical device |
JP2006500978A (ja) * | 2002-08-20 | 2006-01-12 | イグザクテック・インコーポレイテッド | 骨成長誘導物質の運搬および送達用組成物、およびその組成物の製造および適用方法 |
AU2003279823A1 (en) | 2002-10-28 | 2004-05-25 | Northgate Technologies Inc. | Dual-capacity insufflator tube |
US7654975B2 (en) | 2003-04-24 | 2010-02-02 | Northgate Technologies, Inc. | Mixed-gas insufflation system |
US7955616B2 (en) * | 2003-09-23 | 2011-06-07 | Orthocon, Inc. | Absorbable implants and methods for their use in hemostasis and in the treatment of osseous defects |
JP5031367B2 (ja) * | 2003-09-23 | 2012-09-19 | オーソコン・インコーポレイテッド | 吸収性のインプラントならびに止血および骨欠損の処置における、それらの使用 |
JP4928266B2 (ja) | 2003-10-07 | 2012-05-09 | ノースゲート テクノロジーズ インコーポレイテッド | 物質を体腔へ送出するためのシステム及び方法 |
US20050208095A1 (en) * | 2003-11-20 | 2005-09-22 | Angiotech International Ag | Polymer compositions and methods for their use |
US7332179B2 (en) * | 2003-12-12 | 2008-02-19 | Kimberly-Clark Worldwide, Inc. | Tissue products comprising a cleansing composition |
US20050244480A1 (en) * | 2004-04-30 | 2005-11-03 | Kimberly-Clark Worldwide, Inc. | Pre-wipes for improving anal cleansing |
US7642395B2 (en) * | 2004-12-28 | 2010-01-05 | Kimberly-Clark Worldwide, Inc. | Composition and wipe for reducing viscosity of viscoelastic bodily fluids |
US20060140899A1 (en) * | 2004-12-28 | 2006-06-29 | Kimberly-Clark Worldwide, Inc. | Skin cleansing system comprising an anti-adherent formulation and a cationic compound |
US8414907B2 (en) | 2005-04-28 | 2013-04-09 | Warsaw Orthopedic, Inc. | Coatings on medical implants to guide soft tissue healing |
US9119901B2 (en) | 2005-04-28 | 2015-09-01 | Warsaw Orthopedic, Inc. | Surface treatments for promoting selective tissue attachment to medical impants |
JP2008543967A (ja) * | 2005-06-28 | 2008-12-04 | ライフ サイエンス インベンシヨンズ リミテッド | 炎症性皮膚病変を治療するためのスーパーオキシドジスムターゼとカタラーゼとの混合物の使用 |
US7858585B2 (en) * | 2005-11-14 | 2010-12-28 | University Of Delaware | Hydrogels and uses thereof |
US7706852B2 (en) | 2006-01-30 | 2010-04-27 | Nellcor Puritan Bennett Llc | System and method for detection of unstable oxygen saturation |
CA2933737C (en) | 2006-08-04 | 2020-12-29 | Northgate Technologies Inc. | In-dwelling port for access into a body |
US20080241270A1 (en) * | 2007-03-30 | 2008-10-02 | Neal Robert A | Fluid composition for inhibiting surgical adhesion formation and related method of production |
CN102695500A (zh) | 2009-11-09 | 2012-09-26 | 聚光灯技术合伙有限责任公司 | 多糖基水凝胶 |
CA2780274C (en) | 2009-11-09 | 2018-06-26 | Spotlight Technology Partners Llc | Fragmented hydrogels |
WO2014081969A1 (en) | 2012-11-21 | 2014-05-30 | University Of Louisville Research Foundation, Inc | Compositions and methods for reducing oxidative damage |
US9572595B1 (en) | 2014-03-05 | 2017-02-21 | Northgate Technologies Inc. | In-dwelling port for access into a body |
EP3256136A4 (de) | 2015-02-09 | 2018-11-21 | University Of Louisville Research Foundation, Inc. | Ophthalmische zusammensetzungen und verfahren zur reduzierung von oxidativen schäden einer augenlinse |
US10590257B2 (en) | 2016-09-26 | 2020-03-17 | The Board Of Trustees Of The Leland Stanford Junior University | Biomimetic, moldable, self-assembled cellulose silica-based trimeric hydrogels and their use as viscosity modifying carriers in industrial applications |
CN106468668B (zh) * | 2016-09-28 | 2019-03-12 | 北京凯视佳光电设备有限公司 | 工业相机圆柱检测方法 |
EP3746393A4 (de) | 2018-02-02 | 2021-11-03 | Galen Therapeutics Llc | Vorrichtung und verfahren zum schutz von neuronen und zur verminderung von entzündungen und narbenbildung |
Family Cites Families (67)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3784585A (en) * | 1971-10-21 | 1974-01-08 | American Cyanamid Co | Water-degradable resins containing recurring,contiguous,polymerized glycolide units and process for preparing same |
US4371519A (en) * | 1972-06-05 | 1983-02-01 | Hettinger Jr William P | Methods of treating cellular tissue |
US4897308A (en) * | 1975-06-30 | 1990-01-30 | L'oreal | Compositions comprising aqueous dispersions of lipid spheres |
US4563349A (en) * | 1980-07-30 | 1986-01-07 | Takeda Chemical Industries, Ltd. | Superoxide dismutase, its immobilized form, and their production and use |
EP0092918B1 (de) * | 1982-04-22 | 1988-10-19 | Imperial Chemical Industries Plc | Mittel mit verzögerter Freigabe |
US5286763A (en) * | 1983-03-22 | 1994-02-15 | Massachusetts Institute Of Technology | Bioerodible polymers for drug delivery in bone |
JPS6014861A (ja) * | 1983-07-05 | 1985-01-25 | 株式会社日本メデイカル・サプライ | 癒着防止材 |
DE3486452T2 (de) * | 1983-10-03 | 1997-11-06 | Chiron Corp | Superoxiddismutase und deren Expression in Mikroorganismen |
US4511478A (en) * | 1983-11-10 | 1985-04-16 | Genetic Systems Corporation | Polymerizable compounds and methods for preparing synthetic polymers that integrally contain polypeptides |
US4873292A (en) * | 1984-12-28 | 1989-10-10 | Research Development Corporation Of Japan | Antithrombogenic synthetic polymer and process for its preparation |
US4760051A (en) * | 1985-01-24 | 1988-07-26 | Pickart Loren R | Use of GHL-Cu as a wound-healing and anti-inflammatory agent |
CS254355B1 (en) * | 1985-04-10 | 1988-01-15 | Vladimir Saudek | Soluble and biodegradatable copolymeres activated for bond of biologicaly active substances |
JPH084504B2 (ja) * | 1985-04-26 | 1996-01-24 | 味の素株式会社 | 安定化ス−パ−オキサイドジスムタ−ゼ |
IN166447B (de) * | 1985-11-27 | 1990-05-12 | Ethicon Inc | |
US4889722A (en) * | 1985-12-16 | 1989-12-26 | Ethicon, Inc. | Method for inhibiting post-surgical adhesion formation by the topical administration of tissue plasminogen activator |
US4806621A (en) * | 1986-01-21 | 1989-02-21 | Massachusetts Institute Of Technology | Biocompatible, bioerodible, hydrophobic, implantable polyimino carbonate article |
US4976959A (en) * | 1986-05-12 | 1990-12-11 | Burroughs Wellcome Co. | T-PA and SOD in limiting tissue damage |
US4741872A (en) * | 1986-05-16 | 1988-05-03 | The University Of Kentucky Research Foundation | Preparation of biodegradable microspheres useful as carriers for macromolecules |
US5160745A (en) * | 1986-05-16 | 1992-11-03 | The University Of Kentucky Research Foundation | Biodegradable microspheres as a carrier for macromolecules |
IT1198449B (it) * | 1986-10-13 | 1988-12-21 | F I D I Farmaceutici Italiani | Esteri di alcoli polivalenti di acido ialuronico |
US5547988B1 (en) * | 1986-12-23 | 1997-07-15 | Tristrata Inc | Alleviating signs of dermatological aging with glycolic acid lactic acid or citric acid |
US5260204A (en) * | 1987-03-14 | 1993-11-09 | Boehringer Ingelheim International Gmbh | Human manganese superoxide dismutase (hMn-SOD) |
US5223538A (en) * | 1987-03-31 | 1993-06-29 | Duke University | Superoxide dismutase mimic |
US5227405A (en) * | 1987-03-31 | 1993-07-13 | Duke University | Superoxide dismutase mimic |
EP0292964B1 (de) * | 1987-05-28 | 1995-04-05 | Hiroshi Maeda | Superoxid-Dismutase-Derivate, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
IL82834A (en) * | 1987-06-09 | 1990-11-05 | Yissum Res Dev Co | Biodegradable polymeric materials based on polyether glycols,processes for the preparation thereof and surgical artiicles made therefrom |
HU209955B (en) * | 1987-07-01 | 1994-12-28 | Genentech Inc | Process for producing pharmaceutical compositions containing tissue- -plasminogen-activator of poor solubility for inhibiting production and regeneration of deformities |
US5080891A (en) * | 1987-08-03 | 1992-01-14 | Ddi Pharmaceuticals, Inc. | Conjugates of superoxide dismutase coupled to high molecular weight polyalkylene glycols |
US4804691A (en) * | 1987-08-28 | 1989-02-14 | Richards Medical Company | Method for making a biodegradable adhesive for soft living tissue |
US5364622A (en) * | 1987-12-04 | 1994-11-15 | Dr. Karl Thomae Gmbh | Methods for preventing adhesions to organs and parts of organs by application of tissue plasminogen activator and hydroxyethylcellulose hydrogel |
US4888413A (en) * | 1988-01-11 | 1989-12-19 | Domb Abraham J | Poly(propylene glycol fumarate) compositions for biomedical applications |
US4898734A (en) * | 1988-02-29 | 1990-02-06 | Massachusetts Institute Of Technology | Polymer composite for controlled release or membrane formation |
US5057494A (en) * | 1988-08-03 | 1991-10-15 | Ethicon, Inc. | Method for preventing tissue damage after an ischemic episode |
US5213580A (en) * | 1988-08-24 | 1993-05-25 | Endoluminal Therapeutics, Inc. | Biodegradable polymeric endoluminal sealing process |
US5328471A (en) * | 1990-02-26 | 1994-07-12 | Endoluminal Therapeutics, Inc. | Method and apparatus for treatment of focal disease in hollow tubular organs and other tissue lumens |
US4925677A (en) * | 1988-08-31 | 1990-05-15 | Theratech, Inc. | Biodegradable hydrogel matrices for the controlled release of pharmacologically active agents |
US4938763B1 (en) * | 1988-10-03 | 1995-07-04 | Atrix Lab Inc | Biodegradable in-situ forming implants and method of producing the same |
US5135751A (en) * | 1988-11-16 | 1992-08-04 | Mediventures Incorporated | Composition for reducing postsurgical adhesions |
US5126141A (en) * | 1988-11-16 | 1992-06-30 | Mediventures Incorporated | Composition and method for post-surgical adhesion reduction with thermo-irreversible gels of polyoxyalkylene polymers and ionic polysaccharides |
US4911926A (en) * | 1988-11-16 | 1990-03-27 | Mediventures Inc. | Method and composition for reducing postsurgical adhesions |
ZA899326B (en) * | 1988-12-07 | 1991-08-28 | Johnson & Johnson Patient Care | Low molecular weight heparin,heparinoid and hexuronyl hexosaminoglycan sulfate containing adhesion prevention barrier and process |
US5108755A (en) * | 1989-04-27 | 1992-04-28 | Sri International | Biodegradable composites for internal medical use |
IL90193A (en) * | 1989-05-04 | 1993-02-21 | Biomedical Polymers Int | Polurethane-based polymeric materials and biomedical articles and pharmaceutical compositions utilizing the same |
US4994277A (en) * | 1989-10-31 | 1991-02-19 | Pfizer Hospital Products Group, Inc. | Use of xanthan gum for preventing adhesions |
US5175235A (en) * | 1990-06-04 | 1992-12-29 | Nova Pharmaceutical Corporation | Branched polyanhydrides |
WO1991011992A1 (en) * | 1990-02-13 | 1991-08-22 | Zerega Gere S Di | Peritoneal induced medicaments |
US5292516A (en) * | 1990-05-01 | 1994-03-08 | Mediventures, Inc. | Body cavity drug delivery with thermoreversible gels containing polyoxyalkylene copolymers |
US5219564A (en) * | 1990-07-06 | 1993-06-15 | Enzon, Inc. | Poly(alkylene oxide) amino acid copolymers and drug carriers and charged copolymers based thereon |
US5143731A (en) * | 1990-08-07 | 1992-09-01 | Mediventures Incorporated | Body cavity drug delivery with thermo-irreversible polyoxyalkylene and ionic polysaccharide gels |
US5217966A (en) * | 1990-09-13 | 1993-06-08 | The Regents Of The University Of California | Synthetic drug molecules that mimic metalloenzymes |
US5529914A (en) * | 1990-10-15 | 1996-06-25 | The Board Of Regents The Univeristy Of Texas System | Gels for encapsulation of biological materials |
US5410016A (en) * | 1990-10-15 | 1995-04-25 | Board Of Regents, The University Of Texas System | Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers |
US5288502A (en) * | 1991-10-16 | 1994-02-22 | The University Of Texas System | Preparation and uses of multi-phase microspheres |
BR9306038A (pt) * | 1992-02-28 | 1998-01-13 | Univ Texas | Hidrogéis biodegradáveis fotopolimerizáveis como materiais de contato de tecidos e condutores de liberação controlada |
US5384333A (en) * | 1992-03-17 | 1995-01-24 | University Of Miami | Biodegradable injectable drug delivery polymer |
WO1993019660A1 (en) * | 1992-04-03 | 1993-10-14 | Baylor College Of Medicine | Gene therapy using the intestine |
CA2158731C (en) * | 1993-03-23 | 2001-06-05 | Stephen C. Rowe | Apparatus and method for local application of polymeric material to tissue |
ATE169483T1 (de) * | 1993-04-28 | 1998-08-15 | Focal Inc | Vorrichtung, produkt und verwendung betreffend die intraluminale photothermoformgebung |
US5519035A (en) * | 1993-07-02 | 1996-05-21 | Cornell Research Foundation, Inc. | Treatment of stroke or in anticipation of the occurrence of brain ischemia |
ES2172573T3 (es) * | 1993-12-01 | 2002-10-01 | Bioartificial Gel Technologies Inc | Hidrogel basado en albumina. |
US5419917A (en) * | 1994-02-14 | 1995-05-30 | Andrx Pharmaceuticals, Inc. | Controlled release hydrogel formulation |
JP3492787B2 (ja) * | 1994-04-15 | 2004-02-03 | 信越化学工業株式会社 | 固形製剤のコーティング用水性エマルジョンの濃縮方法 |
IL109539A0 (en) * | 1994-05-03 | 1994-08-26 | Yissum Res Dev Co | Substained-release pharmaceutical system for the delivery of antioxidants |
US5478837A (en) | 1994-06-07 | 1995-12-26 | University Of Southern California | Use of quinacrine in preventing adhesion formation |
US5562594A (en) * | 1994-06-10 | 1996-10-08 | Duke University | Shielded mini-applicator system for radioactive source treatment of cancer of the uterine cervix |
JP3145409B2 (ja) * | 1995-03-24 | 2001-03-12 | フォーカル, インコーポレイテッド | 活性酸素阻害剤の制御送達を用いる癒着の低減 |
US5527864A (en) * | 1995-08-08 | 1996-06-18 | Suggs; Laura J. | Poly(propylene fumarate-co-ethylene oxide) |
-
1996
- 1996-03-20 JP JP52950096A patent/JP3145409B2/ja not_active Expired - Lifetime
- 1996-03-20 CA CA002215317A patent/CA2215317C/en not_active Expired - Lifetime
- 1996-03-20 WO PCT/US1996/003813 patent/WO1996029987A1/en active IP Right Grant
- 1996-03-20 DE DE69635301T patent/DE69635301T2/de not_active Expired - Lifetime
- 1996-03-20 AU AU52575/96A patent/AU704222B2/en not_active Expired
- 1996-03-20 EP EP96908878A patent/EP0814774B1/de not_active Expired - Lifetime
- 1996-03-20 AT AT96908878T patent/ATE306903T1/de not_active IP Right Cessation
- 1996-07-29 US US08/689,139 patent/US5785993A/en not_active Expired - Lifetime
-
1998
- 1998-07-27 US US09/123,137 patent/US6780427B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US20010046503A1 (en) | 2001-11-29 |
EP0814774A1 (de) | 1998-01-07 |
WO1996029987A1 (en) | 1996-10-03 |
US5785993A (en) | 1998-07-28 |
JPH10508872A (ja) | 1998-09-02 |
CA2215317C (en) | 2002-07-23 |
AU5257596A (en) | 1996-10-16 |
DE69635301T2 (de) | 2006-07-20 |
AU704222B2 (en) | 1999-04-15 |
US6780427B2 (en) | 2004-08-24 |
ATE306903T1 (de) | 2005-11-15 |
EP0814774B1 (de) | 2005-10-19 |
CA2215317A1 (en) | 1996-10-03 |
JP3145409B2 (ja) | 2001-03-12 |
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