DE69631678D1 - Molekulare klonierung und charakterisierung von molekülen, welche verwandt sind mit relaxin und liganden der insulinfamilie - Google Patents

Molekulare klonierung und charakterisierung von molekülen, welche verwandt sind mit relaxin und liganden der insulinfamilie

Info

Publication number
DE69631678D1
DE69631678D1 DE69631678T DE69631678T DE69631678D1 DE 69631678 D1 DE69631678 D1 DE 69631678D1 DE 69631678 T DE69631678 T DE 69631678T DE 69631678 T DE69631678 T DE 69631678T DE 69631678 D1 DE69631678 D1 DE 69631678D1
Authority
DE
Germany
Prior art keywords
relaxin
related factor
provides
factor
well
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69631678T
Other languages
English (en)
Other versions
DE69631678T2 (de
Inventor
Samuel Davis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Regeneron Pharmaceuticals Inc
Original Assignee
Regeneron Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneron Pharmaceuticals Inc filed Critical Regeneron Pharmaceuticals Inc
Application granted granted Critical
Publication of DE69631678D1 publication Critical patent/DE69631678D1/de
Publication of DE69631678T2 publication Critical patent/DE69631678T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/64—Relaxins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE1996631678 1995-11-03 1996-11-01 Molekulare clonierung und charaterizierung von molekülen, welche verwandt sind mit relaxin und liganden der insulinfamilie Expired - Fee Related DE69631678T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US622195P 1995-11-03 1995-11-03
US6221P 1995-11-03
US1201696P 1996-02-21 1996-02-21
US12016P 1996-02-21
PCT/US1996/017342 WO1997016549A2 (en) 1995-11-03 1996-11-01 Molecular cloning and characterization of molecules related to relaxin and the insulin family of ligands

Publications (2)

Publication Number Publication Date
DE69631678D1 true DE69631678D1 (de) 2004-04-01
DE69631678T2 DE69631678T2 (de) 2005-01-13

Family

ID=26675338

Family Applications (1)

Application Number Title Priority Date Filing Date
DE1996631678 Expired - Fee Related DE69631678T2 (de) 1995-11-03 1996-11-01 Molekulare clonierung und charaterizierung von molekülen, welche verwandt sind mit relaxin und liganden der insulinfamilie

Country Status (10)

Country Link
EP (1) EP0866861B1 (de)
JP (1) JPH11514524A (de)
AT (1) ATE260340T1 (de)
AU (1) AU713773B2 (de)
CA (1) CA2236297A1 (de)
DE (1) DE69631678T2 (de)
DK (1) DK0866861T3 (de)
ES (1) ES2216070T3 (de)
PT (1) PT866861E (de)
WO (1) WO1997016549A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6709659B1 (en) 1996-08-02 2004-03-23 Zymogenetics, Inc. Antibodies that bind testis-specific insulin homolog polypeptides
US5959075A (en) * 1996-08-02 1999-09-28 Zymogenetics, Inc. Testis-specific insulin homolog polypeptides
AU729821B2 (en) * 1996-10-15 2001-02-08 Zymogenetics Inc. Insulin homologs
AU5530198A (en) 1996-12-16 1998-07-15 Zymogenetics Inc. Compositions and methods for stimulating pancreatic islet cell regeneration
US20050032683A1 (en) 2000-10-04 2005-02-10 Amento Edward P. Methods of modulating apoptosis by administration of relaxin agonists or antagonists
US9382305B2 (en) * 2011-07-01 2016-07-05 Bayer Intellectual Property Gmbh Relaxin fusion polypeptides and uses thereof
US20140335108A1 (en) * 2011-12-12 2014-11-13 Trustees Of Boston University Utility of insulin-like 6 (insl6) for the treatment of autoimmune diseases
WO2017201340A2 (en) * 2016-05-18 2017-11-23 Modernatx, Inc. Polynucleotides encoding relaxin

Also Published As

Publication number Publication date
WO1997016549A2 (en) 1997-05-09
AU713773B2 (en) 1999-12-09
EP0866861A2 (de) 1998-09-30
JPH11514524A (ja) 1999-12-14
CA2236297A1 (en) 1997-05-09
EP0866861B1 (de) 2004-02-25
PT866861E (pt) 2004-05-31
AU7526196A (en) 1997-05-22
ES2216070T3 (es) 2004-10-16
DK0866861T3 (da) 2004-06-21
ATE260340T1 (de) 2004-03-15
WO1997016549A3 (en) 1997-06-19
DE69631678T2 (de) 2005-01-13

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