DE69629586D1 - Genexpression von utrophin - Google Patents
Genexpression von utrophinInfo
- Publication number
- DE69629586D1 DE69629586D1 DE69629586T DE69629586T DE69629586D1 DE 69629586 D1 DE69629586 D1 DE 69629586D1 DE 69629586 T DE69629586 T DE 69629586T DE 69629586 T DE69629586 T DE 69629586T DE 69629586 D1 DE69629586 D1 DE 69629586D1
- Authority
- DE
- Germany
- Prior art keywords
- utrophin
- nucleic acid
- gene expression
- actin
- severity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 102000011856 Utrophin Human genes 0.000 title abstract 3
- 108010075653 Utrophin Proteins 0.000 title abstract 3
- 230000014509 gene expression Effects 0.000 title abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 102000007469 Actins Human genes 0.000 abstract 1
- 108010085238 Actins Proteins 0.000 abstract 1
- 102000001039 Dystrophin Human genes 0.000 abstract 1
- 108010069091 Dystrophin Proteins 0.000 abstract 1
- 238000010171 animal model Methods 0.000 abstract 1
- 230000007423 decrease Effects 0.000 abstract 1
- 210000003205 muscle Anatomy 0.000 abstract 1
- 201000006938 muscular dystrophy Diseases 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4707—Muscular dystrophy
- C07K14/4708—Duchenne dystrophy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9525962.8A GB9525962D0 (en) | 1995-12-19 | 1995-12-19 | Gene expression |
| GB9525962 | 1995-12-19 | ||
| GB9615797 | 1996-07-26 | ||
| GBGB9615797.9A GB9615797D0 (en) | 1995-12-19 | 1996-07-26 | Gene expression |
| GBGB9622174.2A GB9622174D0 (en) | 1995-12-19 | 1996-10-24 | Gene expression |
| GB9622174 | 1996-10-24 | ||
| PCT/GB1996/003156 WO1997022696A1 (en) | 1995-12-19 | 1996-12-19 | Utrophin gene expression |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69629586D1 true DE69629586D1 (de) | 2003-09-25 |
| DE69629586T2 DE69629586T2 (de) | 2004-06-24 |
Family
ID=27268039
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69629586T Expired - Fee Related DE69629586T2 (de) | 1995-12-19 | 1996-12-19 | Genexpression von utrophin |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6518413B1 (de) |
| EP (1) | EP0868511B1 (de) |
| JP (1) | JP2000504931A (de) |
| AT (1) | ATE247710T1 (de) |
| AU (1) | AU724525B2 (de) |
| DE (1) | DE69629586T2 (de) |
| DK (1) | DK0868511T3 (de) |
| ES (1) | ES2205070T3 (de) |
| GB (1) | GB9622174D0 (de) |
| WO (1) | WO1997022696A1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9923423D0 (en) * | 1999-10-04 | 1999-12-08 | Isis Innovation | Promoting gene expression |
| EP1287125B1 (de) * | 2000-04-28 | 2009-07-29 | Asklepios Biopharmaceutical, Inc. | Für das dystrophin-minigen kodierende dna-sequenzen und verfahren zu deren verwendung |
| GB2368064B (en) | 2000-09-30 | 2002-11-13 | Imp Cancer Res Tech | DNA Element and Associated Protein |
| WO2002029056A2 (en) | 2000-10-06 | 2002-04-11 | Regents Of The University Of Michigan | Mini-dystrophin nucleic acid and peptide sequences |
| WO2005049850A2 (en) | 2003-11-14 | 2005-06-02 | University Of Washington | Compositions and methods for systemic nucleic acid sequence delivery |
| US7771993B2 (en) * | 2004-01-23 | 2010-08-10 | The Trustees Of The University Of Pennsylvania | Microutrophin and uses thereof |
| BR112020021179A2 (pt) * | 2018-04-16 | 2021-03-02 | The Trustees Of The University Of Pennsylvania | composições e métodos para tratar distrofia muscular de duchenne |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9408573D0 (en) * | 1994-04-29 | 1994-06-22 | Gatsby Charitable Foundation | Identification, production and use of saponin gylcosyl hydrolases |
-
1996
- 1996-10-24 GB GBGB9622174.2A patent/GB9622174D0/en active Pending
- 1996-12-19 JP JP09522591A patent/JP2000504931A/ja not_active Ceased
- 1996-12-19 EP EP96942508A patent/EP0868511B1/de not_active Expired - Lifetime
- 1996-12-19 AT AT96942508T patent/ATE247710T1/de not_active IP Right Cessation
- 1996-12-19 AU AU11644/97A patent/AU724525B2/en not_active Ceased
- 1996-12-19 US US09/091,501 patent/US6518413B1/en not_active Expired - Fee Related
- 1996-12-19 WO PCT/GB1996/003156 patent/WO1997022696A1/en active IP Right Grant
- 1996-12-19 DK DK96942508T patent/DK0868511T3/da active
- 1996-12-19 ES ES96942508T patent/ES2205070T3/es not_active Expired - Lifetime
- 1996-12-19 DE DE69629586T patent/DE69629586T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0868511A1 (de) | 1998-10-07 |
| AU724525B2 (en) | 2000-09-21 |
| DE69629586T2 (de) | 2004-06-24 |
| EP0868511B1 (de) | 2003-08-20 |
| DK0868511T3 (da) | 2003-12-08 |
| WO1997022696A1 (en) | 1997-06-26 |
| ES2205070T3 (es) | 2004-05-01 |
| ATE247710T1 (de) | 2003-09-15 |
| US6518413B1 (en) | 2003-02-11 |
| GB9622174D0 (en) | 1996-12-18 |
| JP2000504931A (ja) | 2000-04-25 |
| AU1164497A (en) | 1997-07-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8339 | Ceased/non-payment of the annual fee |