DE69624914D1 - Vorrichtung und verfahren für die biospezifische entfernung von heparin - Google Patents

Vorrichtung und verfahren für die biospezifische entfernung von heparin

Info

Publication number
DE69624914D1
DE69624914D1 DE69624914T DE69624914T DE69624914D1 DE 69624914 D1 DE69624914 D1 DE 69624914D1 DE 69624914 T DE69624914 T DE 69624914T DE 69624914 T DE69624914 T DE 69624914T DE 69624914 D1 DE69624914 D1 DE 69624914D1
Authority
DE
Germany
Prior art keywords
heparin
blood
extracorporeal
heart
heparinized
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69624914T
Other languages
English (en)
Other versions
DE69624914T2 (de
Inventor
Peter Grandics
Susan Szathmary
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of DE69624914D1 publication Critical patent/DE69624914D1/de
Publication of DE69624914T2 publication Critical patent/DE69624914T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/81—Protease inhibitors
    • G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • G01N2333/811—Serine protease (E.C. 3.4.21) inhibitors
    • G01N2333/8121—Serpins
    • G01N2333/8128—Antithrombin III
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/38—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence, e.g. gluco- or galactomannans, e.g. Konjac gum, Locust bean gum, Guar gum
    • G01N2400/40—Glycosaminoglycans, i.e. GAG or mucopolysaccharides, e.g. chondroitin sulfate, dermatan sulfate, hyaluronic acid, heparin, heparan sulfate, and related sulfated polysaccharides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/962—Prevention or removal of interfering materials or reactants or other treatment to enhance results, e.g. determining or preventing nonspecific binding
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • External Artificial Organs (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
DE69624914T 1995-05-09 1996-05-08 Vorrichtung und verfahren für die biospezifische entfernung von heparin Expired - Fee Related DE69624914T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/437,891 US5801063A (en) 1995-05-09 1995-05-09 Device and process for the biospecific removal of heparin
PCT/US1996/006515 WO1996035954A1 (en) 1995-05-09 1996-05-08 A device and process for the biospecific removal of heparin

Publications (2)

Publication Number Publication Date
DE69624914D1 true DE69624914D1 (de) 2003-01-02
DE69624914T2 DE69624914T2 (de) 2003-09-18

Family

ID=23738352

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69624914T Expired - Fee Related DE69624914T2 (de) 1995-05-09 1996-05-08 Vorrichtung und verfahren für die biospezifische entfernung von heparin

Country Status (7)

Country Link
US (1) US5801063A (de)
EP (1) EP0824698B1 (de)
JP (1) JP3899128B2 (de)
AT (1) ATE228246T1 (de)
DE (1) DE69624914T2 (de)
DK (1) DK0824698T3 (de)
WO (1) WO1996035954A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5839443A (en) * 1996-05-16 1998-11-24 The Trustees Of Columbia University In The City Of New York Method for inhibiting thrombosis in a patient whose blood is subjected to extracorporeal circulation
EP1061972A1 (de) 1998-03-16 2000-12-27 Medtronic, Inc. Hämostatisches system und komponenten für einen extrakorporalen kreislauf
US20030069601A1 (en) * 1998-12-15 2003-04-10 Closys Corporation Clotting cascade initiating apparatus and methods of use
FR2804328B1 (fr) 2000-01-27 2002-03-15 Hospal Ind Membrane semi-permeable non thrombogene et procede de fabrication
JP4262979B2 (ja) * 2000-11-21 2009-05-13 ザ・テキサス・エイ・アンド・エム・ユニバーシテイ・システム Ｆｇｆアフィニティークロマトグラフィー
US6761700B2 (en) * 2001-02-09 2004-07-13 Orqis Medical Corporation Extra-corporeal vascular conduit
US20100221697A1 (en) * 2005-01-12 2010-09-02 BioVec Transfusions, LLC Composition for preserving platelets and method of using and storing the same
US8129104B2 (en) * 2005-01-12 2012-03-06 Biovec Transfusion, Llc Platelet preservation composition comprising a short to ultra-short acting antiplatelet agent and anticoagulant with hemoglobin
US8142992B2 (en) * 2005-01-12 2012-03-27 Biovec Transfusion, Llc Platelet preservation package comprising a short to ultra-short acting antiplatelet agent and anticoagulant with an oxygen carrier
EP1835803A4 (de) * 2005-01-12 2011-11-30 Biovec Llc Zusammensetzung zur konservierung von blutplättchen und verwendungsverfahren dafür
MX2007009177A (es) 2005-01-28 2008-03-10 Galen Bio Inc Composiciones inmunologicamente activas.
US8431334B2 (en) * 2006-01-12 2013-04-30 Biovec Transfusion, Llc Method for removing antiplatelet agent and anticoagulant from a platelet composition by diafiltration
US9095818B2 (en) * 2009-06-15 2015-08-04 Biovec Transfusion, Llc Method of filtering platelets to remove antiplatelet and anticoagulant agents
WO2012162789A1 (en) 2011-06-01 2012-12-06 University Of British Columbia Polymers for reversing heparin-based anticoagulation
TWI507641B (zh) 2012-04-17 2015-11-11 Delta Electronics Inc 照明裝置及產生白光之方法
US9511087B2 (en) * 2012-08-03 2016-12-06 Revo Biologics, Inc. Use of antithrombin in extracorporeal membrane oxygenation
US10151749B2 (en) * 2015-08-05 2018-12-11 Alfaisal University Method and kit for the detection of microorganisms
EP3691775A1 (de) 2017-10-05 2020-08-12 Fresenius Medical Care Holdings, Inc. Polysulfon-urethan-copolymer, membranen und produkte damit und verfahren zur herstellung und verwendung davon

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4200690A (en) * 1976-12-16 1980-04-29 Millipore Corporation Immunoassay with membrane immobilized antibody
US4411786A (en) * 1979-09-07 1983-10-25 Russell Richard T Method and apparatus for separating blood from other fluids during operative procedures
US4450104A (en) * 1980-09-30 1984-05-22 Cutter Laboratories, Inc. Water insoluble gel matrix containing lectin bound to antithrombin
US4326532A (en) * 1980-10-06 1982-04-27 Minnesota Mining And Manufacturing Company Antithrombogenic articles
US5229268A (en) * 1986-07-14 1993-07-20 Abbott Laboratories Method for diagnostic immunoassay by solid phase separation
GB9417185D0 (en) * 1994-08-25 1994-10-12 Adaptive Audio Ltd Sounds recording and reproduction systems

Also Published As

Publication number Publication date
JPH11505138A (ja) 1999-05-18
DK0824698T3 (da) 2003-03-17
JP3899128B2 (ja) 2007-03-28
EP0824698B1 (de) 2002-11-20
WO1996035954A1 (en) 1996-11-14
US5801063A (en) 1998-09-01
ATE228246T1 (de) 2002-12-15
DE69624914T2 (de) 2003-09-18
EP0824698A1 (de) 1998-02-25
EP0824698A4 (de) 1999-04-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee