ATE228246T1 - Vorrichtung und verfahren für die biospezifische entfernung von heparin - Google Patents
Vorrichtung und verfahren für die biospezifische entfernung von heparinInfo
- Publication number
- ATE228246T1 ATE228246T1 AT96915609T AT96915609T ATE228246T1 AT E228246 T1 ATE228246 T1 AT E228246T1 AT 96915609 T AT96915609 T AT 96915609T AT 96915609 T AT96915609 T AT 96915609T AT E228246 T1 ATE228246 T1 AT E228246T1
- Authority
- AT
- Austria
- Prior art keywords
- heparin
- blood
- extracorporeal
- heart
- heparinized
- Prior art date
Links
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 title abstract 6
- 229960002897 heparin Drugs 0.000 title abstract 6
- 229920000669 heparin Polymers 0.000 title abstract 6
- 238000000034 method Methods 0.000 title abstract 2
- 239000008280 blood Substances 0.000 abstract 5
- 210000004369 blood Anatomy 0.000 abstract 5
- 102000004411 Antithrombin III Human genes 0.000 abstract 2
- 108090000935 Antithrombin III Proteins 0.000 abstract 2
- 229960005348 antithrombin iii Drugs 0.000 abstract 2
- 238000001631 haemodialysis Methods 0.000 abstract 2
- 230000000322 hemodialysis Effects 0.000 abstract 2
- 206010067484 Adverse reaction Diseases 0.000 abstract 1
- 206010053567 Coagulopathies Diseases 0.000 abstract 1
- 230000006838 adverse reaction Effects 0.000 abstract 1
- 230000010100 anticoagulation Effects 0.000 abstract 1
- 230000035602 clotting Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000009885 systemic effect Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/81—Protease inhibitors
- G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- G01N2333/811—Serine protease (E.C. 3.4.21) inhibitors
- G01N2333/8121—Serpins
- G01N2333/8128—Antithrombin III
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
- G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- G01N2400/38—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence, e.g. gluco- or galactomannans, Konjac gum, Locust bean gum or Guar gum
- G01N2400/40—Glycosaminoglycans, i.e. GAG or mucopolysaccharides, e.g. chondroitin sulfate, dermatan sulfate, hyaluronic acid, heparin, heparan sulfate, and related sulfated polysaccharides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/962—Prevention or removal of interfering materials or reactants or other treatment to enhance results, e.g. determining or preventing nonspecific binding
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- External Artificial Organs (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/437,891 US5801063A (en) | 1995-05-09 | 1995-05-09 | Device and process for the biospecific removal of heparin |
PCT/US1996/006515 WO1996035954A1 (en) | 1995-05-09 | 1996-05-08 | A device and process for the biospecific removal of heparin |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE228246T1 true ATE228246T1 (de) | 2002-12-15 |
Family
ID=23738352
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT96915609T ATE228246T1 (de) | 1995-05-09 | 1996-05-08 | Vorrichtung und verfahren für die biospezifische entfernung von heparin |
Country Status (7)
Country | Link |
---|---|
US (1) | US5801063A (de) |
EP (1) | EP0824698B1 (de) |
JP (1) | JP3899128B2 (de) |
AT (1) | ATE228246T1 (de) |
DE (1) | DE69624914T2 (de) |
DK (1) | DK0824698T3 (de) |
WO (1) | WO1996035954A1 (de) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5839443A (en) * | 1996-05-16 | 1998-11-24 | The Trustees Of Columbia University In The City Of New York | Method for inhibiting thrombosis in a patient whose blood is subjected to extracorporeal circulation |
WO1999047190A1 (en) * | 1998-03-16 | 1999-09-23 | Medtronic, Inc. | Hemostatic system and components for extracorporeal circuit |
US20030069601A1 (en) * | 1998-12-15 | 2003-04-10 | Closys Corporation | Clotting cascade initiating apparatus and methods of use |
FR2804328B1 (fr) | 2000-01-27 | 2002-03-15 | Hospal Ind | Membrane semi-permeable non thrombogene et procede de fabrication |
AU2002236477A1 (en) | 2000-11-21 | 2002-06-03 | The Texas A & M University System | Fgf-affinity chromatography |
US6761700B2 (en) * | 2001-02-09 | 2004-07-13 | Orqis Medical Corporation | Extra-corporeal vascular conduit |
US20100221697A1 (en) * | 2005-01-12 | 2010-09-02 | BioVec Transfusions, LLC | Composition for preserving platelets and method of using and storing the same |
US8129104B2 (en) * | 2005-01-12 | 2012-03-06 | Biovec Transfusion, Llc | Platelet preservation composition comprising a short to ultra-short acting antiplatelet agent and anticoagulant with hemoglobin |
US8142992B2 (en) * | 2005-01-12 | 2012-03-27 | Biovec Transfusion, Llc | Platelet preservation package comprising a short to ultra-short acting antiplatelet agent and anticoagulant with an oxygen carrier |
US7964338B2 (en) * | 2005-01-12 | 2011-06-21 | Biovec Transfusion, Llc | Platelet preservation composition containing eptifibatide, a reversible factor IIa inhibitor and a hemoglobin oxygen carrier |
AU2006207891C1 (en) | 2005-01-28 | 2011-09-01 | Galen Bio, Inc. | Immunologically active compositions |
US9095818B2 (en) * | 2009-06-15 | 2015-08-04 | Biovec Transfusion, Llc | Method of filtering platelets to remove antiplatelet and anticoagulant agents |
US8431334B2 (en) * | 2006-01-12 | 2013-04-30 | Biovec Transfusion, Llc | Method for removing antiplatelet agent and anticoagulant from a platelet composition by diafiltration |
WO2012162789A1 (en) * | 2011-06-01 | 2012-12-06 | University Of British Columbia | Polymers for reversing heparin-based anticoagulation |
TWI507641B (zh) | 2012-04-17 | 2015-11-11 | Delta Electronics Inc | 照明裝置及產生白光之方法 |
BR112015002321A2 (pt) | 2012-08-03 | 2019-10-22 | Lfb Usa Inc | uso de antitrombina recombinante |
US10151749B2 (en) * | 2015-08-05 | 2018-12-11 | Alfaisal University | Method and kit for the detection of microorganisms |
WO2019070507A1 (en) | 2017-10-05 | 2019-04-11 | Fresenius Medical Care Holdings, Inc. | POLYSULFONE-URETHANE COPOLYMER, MEMBRANES AND INCORPORATING PRODUCTS, AND METHODS OF MAKING AND USING THE SAME |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4200690A (en) * | 1976-12-16 | 1980-04-29 | Millipore Corporation | Immunoassay with membrane immobilized antibody |
US4411786A (en) * | 1979-09-07 | 1983-10-25 | Russell Richard T | Method and apparatus for separating blood from other fluids during operative procedures |
US4450104A (en) * | 1980-09-30 | 1984-05-22 | Cutter Laboratories, Inc. | Water insoluble gel matrix containing lectin bound to antithrombin |
US4326532A (en) * | 1980-10-06 | 1982-04-27 | Minnesota Mining And Manufacturing Company | Antithrombogenic articles |
US5229268A (en) * | 1986-07-14 | 1993-07-20 | Abbott Laboratories | Method for diagnostic immunoassay by solid phase separation |
GB9417185D0 (en) * | 1994-08-25 | 1994-10-12 | Adaptive Audio Ltd | Sounds recording and reproduction systems |
-
1995
- 1995-05-09 US US08/437,891 patent/US5801063A/en not_active Expired - Lifetime
-
1996
- 1996-05-08 WO PCT/US1996/006515 patent/WO1996035954A1/en active IP Right Grant
- 1996-05-08 EP EP96915609A patent/EP0824698B1/de not_active Expired - Lifetime
- 1996-05-08 AT AT96915609T patent/ATE228246T1/de not_active IP Right Cessation
- 1996-05-08 JP JP53423096A patent/JP3899128B2/ja not_active Expired - Fee Related
- 1996-05-08 DE DE69624914T patent/DE69624914T2/de not_active Expired - Fee Related
- 1996-05-08 DK DK96915609T patent/DK0824698T3/da active
Also Published As
Publication number | Publication date |
---|---|
JPH11505138A (ja) | 1999-05-18 |
JP3899128B2 (ja) | 2007-03-28 |
EP0824698A1 (de) | 1998-02-25 |
US5801063A (en) | 1998-09-01 |
EP0824698B1 (de) | 2002-11-20 |
WO1996035954A1 (en) | 1996-11-14 |
EP0824698A4 (de) | 1999-04-14 |
DE69624914T2 (de) | 2003-09-18 |
DK0824698T3 (da) | 2003-03-17 |
DE69624914D1 (de) | 2003-01-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 0824698 Country of ref document: EP |
|
REN | Ceased due to non-payment of the annual fee |