DE69623650D1 - Verfahren zum testen einer zellprobe - Google Patents

Verfahren zum testen einer zellprobe

Info

Publication number
DE69623650D1
DE69623650D1 DE69623650T DE69623650T DE69623650D1 DE 69623650 D1 DE69623650 D1 DE 69623650D1 DE 69623650 T DE69623650 T DE 69623650T DE 69623650 T DE69623650 T DE 69623650T DE 69623650 D1 DE69623650 D1 DE 69623650D1
Authority
DE
Germany
Prior art keywords
cell
cells
data
populations
testing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69623650T
Other languages
English (en)
Other versions
DE69623650T2 (de
Inventor
Ian Basil Shine
Thomas Adam Shine
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9526720.9A external-priority patent/GB9526720D0/en
Priority claimed from GBGB9526649.0A external-priority patent/GB9526649D0/en
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of DE69623650D1 publication Critical patent/DE69623650D1/de
Publication of DE69623650T2 publication Critical patent/DE69623650T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/1031Investigating individual particles by measuring electrical or magnetic effects
    • G01N15/12Investigating individual particles by measuring electrical or magnetic effects by observing changes in resistance or impedance across apertures when traversed by individual particles, e.g. by using the Coulter principle
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/012Red blood cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N2015/1022Measurement of deformation of individual particles by non-optical means
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N2015/1024Counting particles by non-optical means
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N2015/1029Particle size
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N2015/103Particle shape

Landscapes

  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE69623650T 1995-12-29 1996-12-27 Verfahren zum testen einer zellprobe Expired - Lifetime DE69623650T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9526720.9A GB9526720D0 (en) 1995-12-29 1995-12-29 Method for testing a cell sample
GBGB9526649.0A GB9526649D0 (en) 1995-12-29 1995-12-29 Method for testing a cell sample
PCT/GB1996/003257 WO1997024601A1 (en) 1995-12-29 1996-12-27 Method for testing a cell sample

Publications (2)

Publication Number Publication Date
DE69623650D1 true DE69623650D1 (de) 2002-10-17
DE69623650T2 DE69623650T2 (de) 2003-02-13

Family

ID=26308401

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69623650T Expired - Lifetime DE69623650T2 (de) 1995-12-29 1996-12-27 Verfahren zum testen einer zellprobe
DE69635391T Expired - Lifetime DE69635391T2 (de) 1995-12-29 1996-12-27 Verfahren zur Untersuchung einer Zellprobe

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69635391T Expired - Lifetime DE69635391T2 (de) 1995-12-29 1996-12-27 Verfahren zur Untersuchung einer Zellprobe

Country Status (8)

Country Link
US (1) US6422065B1 (de)
EP (2) EP1180678B1 (de)
JP (1) JP4160117B2 (de)
AT (2) ATE308746T1 (de)
AU (1) AU714953B2 (de)
CA (1) CA2240573C (de)
DE (2) DE69623650T2 (de)
WO (1) WO1997024601A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2322910B1 (de) 1998-12-29 2019-03-13 Ian Basil Shine Ein Verfahren zur Analyse freier Zellen
GB9828765D0 (en) * 1998-12-29 1999-02-17 Shine Thomas A A method of testing a cell sample
US7542131B2 (en) * 2003-06-23 2009-06-02 Sewon Meditech, Inc. Apparatus for measuring blood cell deformability
US8372600B2 (en) 2004-03-05 2013-02-12 The Research Foundation Of State University Of New York Method and apparatus for measuring changes in cell volume
EP1720998A4 (de) * 2004-03-05 2009-05-06 Univ New York State Res Found Verfahren und vorrichtung zur messung von änderungen des zellvolumens
ITUD20050118A1 (it) * 2005-07-13 2007-01-14 Sire Analytical Systems Srl Procedimento per la taratura di macchine per l' analisi di parametri del sangue connessi alla densita' del sangue, quali la velocita' di eritrosedimentazione e/o di aggregazione dei globuli rossi
US7523640B2 (en) * 2005-08-01 2009-04-28 Baker Hughes Incorporated Acoustic fluid analyzer
US7614302B2 (en) * 2005-08-01 2009-11-10 Baker Hughes Incorporated Acoustic fluid analysis method
CA2665053C (en) * 2006-09-29 2016-08-23 The Administrators Of The Tulane Educational Fund Methods and devices for simultaneously monitoring the characteristics of microscopic particles in suspension and the characteristics of soluble components during reactions
CA3121784A1 (en) * 2018-12-05 2020-06-11 Thomas Adam Shine Cell scanning technologies and methods of use thereof
CA3136353A1 (en) * 2019-04-11 2020-10-15 Ian Basil Shine Cell membrane permeability restoring therapy

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3502412A (en) 1967-10-16 1970-03-24 Abbott Lab Method and apparatus for measuring osmotic fragility of red blood cells by constantly reducing the concentration of the saline solution suspending the cells
CA988319A (en) * 1973-10-11 1976-05-04 Tomas Hirschfeld System for differentiating particles
US3851246A (en) 1973-11-26 1974-11-26 Us Navy Method of predicting the post transfusion viability of preserved erythrocytes and other similar cells
GB1481480A (en) 1974-02-02 1977-07-27 Kernforschungsanlage Juelich Process and apparatus for increasing the permeability of the membrane of cells of organisms
DE2739834C2 (de) 1977-09-03 1981-12-03 Wigo Gottlob Widmann & Söhne GmbH und Co KG, 7730 Villingen-Schwenningen Gerät zum Bereiten von Kaffee oder Tee
US4271001A (en) 1978-03-23 1981-06-02 Asahi Kasei Kogyo Kabushiki Kaisha Apparatus for measuring membrane characteristics of vesicles
US4343782A (en) * 1978-04-20 1982-08-10 Shapiro Howard M Cytological assay procedure
US4240027A (en) 1978-08-31 1980-12-16 The United States Of America As Represented By The Secretary Of The Army Electromagnetic method for the noninvasive analysis of cell membrane physiology and pharmacology
US4298836A (en) * 1979-11-23 1981-11-03 Coulter Electronics, Inc. Particle shape determination
US4278936A (en) * 1980-02-05 1981-07-14 Coulter Electronics, Inc. Biological cell parameter change test method and apparatus
US4374644A (en) * 1981-04-06 1983-02-22 Coulter Electronics, Inc. Blood cell volume monitoring
US4535284A (en) * 1981-07-10 1985-08-13 Coulter Electronics, Inc. High and low frequency analysis of osmotic stress of cells
DE3215719C2 (de) * 1982-04-28 1984-01-26 Holger Dr. 5100 Aachen Kiesewetter Meßeinrichtung zur Messung des Verformungsvermögens von roten Blutkörperchen
US4525666A (en) * 1982-05-03 1985-06-25 Coulter Electronics, Inc. Cell breakdown
US4528274A (en) * 1982-07-06 1985-07-09 Coulter Electronics, Inc. Multi-purpose blood diluent and lysing agent for differential determination of lymphoid-myeloid population of leukocytes
GB8408529D0 (en) * 1984-04-03 1984-05-16 Health Lab Service Board Concentration of biological particles
US4791355A (en) * 1986-10-21 1988-12-13 Coulter Electronics Inc. Particle analyzer for measuring the resistance and reactance of a particle
US5223398A (en) * 1987-03-13 1993-06-29 Coulter Corporation Method for screening cells or formed bodies for enumeration of populations expressing selected characteristics
JP2667867B2 (ja) * 1988-03-30 1997-10-27 東亜医用電子株式会社 粒子解析装置
US5006460A (en) * 1988-05-26 1991-04-09 Pantox Corporation Method for measuring DNA damage in single cells
JP2799191B2 (ja) * 1989-08-24 1998-09-17 オリンパス光学工業株式会社 細胞内イオンの2次元濃度分布像を形成する方法
US5548661A (en) * 1991-07-12 1996-08-20 Price; Jeffrey H. Operator independent image cytometer
JP2565844B2 (ja) * 1992-02-07 1996-12-18 アボツト・ラボラトリーズ 細胞溶解処理条件下で異種細胞集団を正確に計数し,感受性に関する格付けを行う方法
US5369014A (en) * 1992-08-17 1994-11-29 Beth Israel Hospital Assoc. In-vitro method for determining a surreptitious use of exogenous erythropoiesis stimulating agents by a normal living subject
US5532139A (en) 1992-10-30 1996-07-02 Micro-Med, Inc. Micro lysis-analysis process to measure cell characteristics and diagnose diseases
US5595866A (en) 1994-05-27 1997-01-21 Methodist Hospital Of Indiana, Inc. Step-wise method to remove cryoprotectant from sperm

Also Published As

Publication number Publication date
EP1180678B1 (de) 2005-11-02
EP0870187A1 (de) 1998-10-14
EP1180678A3 (de) 2004-01-14
US20020035879A1 (en) 2002-03-28
DE69623650T2 (de) 2003-02-13
ATE308746T1 (de) 2005-11-15
US6422065B1 (en) 2002-07-23
EP1180678A2 (de) 2002-02-20
DE69635391D1 (de) 2005-12-08
CA2240573A1 (en) 1997-07-10
WO1997024601A1 (en) 1997-07-10
CA2240573C (en) 2004-11-09
AU1384797A (en) 1997-07-28
ATE224050T1 (de) 2002-09-15
AU714953B2 (en) 2000-01-13
DE69635391T2 (de) 2006-08-03
JP2000502797A (ja) 2000-03-07
EP0870187B1 (de) 2002-09-11
JP4160117B2 (ja) 2008-10-01

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