DE69623650D1 - Verfahren zum testen einer zellprobe - Google Patents
Verfahren zum testen einer zellprobeInfo
- Publication number
- DE69623650D1 DE69623650D1 DE69623650T DE69623650T DE69623650D1 DE 69623650 D1 DE69623650 D1 DE 69623650D1 DE 69623650 T DE69623650 T DE 69623650T DE 69623650 T DE69623650 T DE 69623650T DE 69623650 D1 DE69623650 D1 DE 69623650D1
- Authority
- DE
- Germany
- Prior art keywords
- cell
- cells
- data
- populations
- testing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title abstract 3
- 230000004075 alteration Effects 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 230000007613 environmental effect Effects 0.000 abstract 1
- 230000001766 physiological effect Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/1031—Investigating individual particles by measuring electrical or magnetic effects
- G01N15/12—Investigating individual particles by measuring electrical or magnetic effects by observing changes in resistance or impedance across apertures when traversed by individual particles, e.g. by using the Coulter principle
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
- G01N2015/012—Red blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1022—Measurement of deformation of individual particles by non-optical means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1024—Counting particles by non-optical means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1029—Particle size
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/103—Particle shape
Landscapes
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9526720.9A GB9526720D0 (en) | 1995-12-29 | 1995-12-29 | Method for testing a cell sample |
GBGB9526649.0A GB9526649D0 (en) | 1995-12-29 | 1995-12-29 | Method for testing a cell sample |
PCT/GB1996/003257 WO1997024601A1 (en) | 1995-12-29 | 1996-12-27 | Method for testing a cell sample |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69623650D1 true DE69623650D1 (de) | 2002-10-17 |
DE69623650T2 DE69623650T2 (de) | 2003-02-13 |
Family
ID=26308401
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69623650T Expired - Lifetime DE69623650T2 (de) | 1995-12-29 | 1996-12-27 | Verfahren zum testen einer zellprobe |
DE69635391T Expired - Lifetime DE69635391T2 (de) | 1995-12-29 | 1996-12-27 | Verfahren zur Untersuchung einer Zellprobe |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69635391T Expired - Lifetime DE69635391T2 (de) | 1995-12-29 | 1996-12-27 | Verfahren zur Untersuchung einer Zellprobe |
Country Status (8)
Country | Link |
---|---|
US (1) | US6422065B1 (de) |
EP (2) | EP1180678B1 (de) |
JP (1) | JP4160117B2 (de) |
AT (2) | ATE308746T1 (de) |
AU (1) | AU714953B2 (de) |
CA (1) | CA2240573C (de) |
DE (2) | DE69623650T2 (de) |
WO (1) | WO1997024601A1 (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2322910B1 (de) | 1998-12-29 | 2019-03-13 | Ian Basil Shine | Ein Verfahren zur Analyse freier Zellen |
GB9828765D0 (en) * | 1998-12-29 | 1999-02-17 | Shine Thomas A | A method of testing a cell sample |
US7542131B2 (en) * | 2003-06-23 | 2009-06-02 | Sewon Meditech, Inc. | Apparatus for measuring blood cell deformability |
US8372600B2 (en) | 2004-03-05 | 2013-02-12 | The Research Foundation Of State University Of New York | Method and apparatus for measuring changes in cell volume |
EP1720998A4 (de) * | 2004-03-05 | 2009-05-06 | Univ New York State Res Found | Verfahren und vorrichtung zur messung von änderungen des zellvolumens |
ITUD20050118A1 (it) * | 2005-07-13 | 2007-01-14 | Sire Analytical Systems Srl | Procedimento per la taratura di macchine per l' analisi di parametri del sangue connessi alla densita' del sangue, quali la velocita' di eritrosedimentazione e/o di aggregazione dei globuli rossi |
US7523640B2 (en) * | 2005-08-01 | 2009-04-28 | Baker Hughes Incorporated | Acoustic fluid analyzer |
US7614302B2 (en) * | 2005-08-01 | 2009-11-10 | Baker Hughes Incorporated | Acoustic fluid analysis method |
CA2665053C (en) * | 2006-09-29 | 2016-08-23 | The Administrators Of The Tulane Educational Fund | Methods and devices for simultaneously monitoring the characteristics of microscopic particles in suspension and the characteristics of soluble components during reactions |
CA3121784A1 (en) * | 2018-12-05 | 2020-06-11 | Thomas Adam Shine | Cell scanning technologies and methods of use thereof |
CA3136353A1 (en) * | 2019-04-11 | 2020-10-15 | Ian Basil Shine | Cell membrane permeability restoring therapy |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3502412A (en) | 1967-10-16 | 1970-03-24 | Abbott Lab | Method and apparatus for measuring osmotic fragility of red blood cells by constantly reducing the concentration of the saline solution suspending the cells |
CA988319A (en) * | 1973-10-11 | 1976-05-04 | Tomas Hirschfeld | System for differentiating particles |
US3851246A (en) | 1973-11-26 | 1974-11-26 | Us Navy | Method of predicting the post transfusion viability of preserved erythrocytes and other similar cells |
GB1481480A (en) | 1974-02-02 | 1977-07-27 | Kernforschungsanlage Juelich | Process and apparatus for increasing the permeability of the membrane of cells of organisms |
DE2739834C2 (de) | 1977-09-03 | 1981-12-03 | Wigo Gottlob Widmann & Söhne GmbH und Co KG, 7730 Villingen-Schwenningen | Gerät zum Bereiten von Kaffee oder Tee |
US4271001A (en) | 1978-03-23 | 1981-06-02 | Asahi Kasei Kogyo Kabushiki Kaisha | Apparatus for measuring membrane characteristics of vesicles |
US4343782A (en) * | 1978-04-20 | 1982-08-10 | Shapiro Howard M | Cytological assay procedure |
US4240027A (en) | 1978-08-31 | 1980-12-16 | The United States Of America As Represented By The Secretary Of The Army | Electromagnetic method for the noninvasive analysis of cell membrane physiology and pharmacology |
US4298836A (en) * | 1979-11-23 | 1981-11-03 | Coulter Electronics, Inc. | Particle shape determination |
US4278936A (en) * | 1980-02-05 | 1981-07-14 | Coulter Electronics, Inc. | Biological cell parameter change test method and apparatus |
US4374644A (en) * | 1981-04-06 | 1983-02-22 | Coulter Electronics, Inc. | Blood cell volume monitoring |
US4535284A (en) * | 1981-07-10 | 1985-08-13 | Coulter Electronics, Inc. | High and low frequency analysis of osmotic stress of cells |
DE3215719C2 (de) * | 1982-04-28 | 1984-01-26 | Holger Dr. 5100 Aachen Kiesewetter | Meßeinrichtung zur Messung des Verformungsvermögens von roten Blutkörperchen |
US4525666A (en) * | 1982-05-03 | 1985-06-25 | Coulter Electronics, Inc. | Cell breakdown |
US4528274A (en) * | 1982-07-06 | 1985-07-09 | Coulter Electronics, Inc. | Multi-purpose blood diluent and lysing agent for differential determination of lymphoid-myeloid population of leukocytes |
GB8408529D0 (en) * | 1984-04-03 | 1984-05-16 | Health Lab Service Board | Concentration of biological particles |
US4791355A (en) * | 1986-10-21 | 1988-12-13 | Coulter Electronics Inc. | Particle analyzer for measuring the resistance and reactance of a particle |
US5223398A (en) * | 1987-03-13 | 1993-06-29 | Coulter Corporation | Method for screening cells or formed bodies for enumeration of populations expressing selected characteristics |
JP2667867B2 (ja) * | 1988-03-30 | 1997-10-27 | 東亜医用電子株式会社 | 粒子解析装置 |
US5006460A (en) * | 1988-05-26 | 1991-04-09 | Pantox Corporation | Method for measuring DNA damage in single cells |
JP2799191B2 (ja) * | 1989-08-24 | 1998-09-17 | オリンパス光学工業株式会社 | 細胞内イオンの2次元濃度分布像を形成する方法 |
US5548661A (en) * | 1991-07-12 | 1996-08-20 | Price; Jeffrey H. | Operator independent image cytometer |
JP2565844B2 (ja) * | 1992-02-07 | 1996-12-18 | アボツト・ラボラトリーズ | 細胞溶解処理条件下で異種細胞集団を正確に計数し,感受性に関する格付けを行う方法 |
US5369014A (en) * | 1992-08-17 | 1994-11-29 | Beth Israel Hospital Assoc. | In-vitro method for determining a surreptitious use of exogenous erythropoiesis stimulating agents by a normal living subject |
US5532139A (en) | 1992-10-30 | 1996-07-02 | Micro-Med, Inc. | Micro lysis-analysis process to measure cell characteristics and diagnose diseases |
US5595866A (en) | 1994-05-27 | 1997-01-21 | Methodist Hospital Of Indiana, Inc. | Step-wise method to remove cryoprotectant from sperm |
-
1996
- 1996-12-27 EP EP01123393A patent/EP1180678B1/de not_active Expired - Lifetime
- 1996-12-27 AT AT01123393T patent/ATE308746T1/de not_active IP Right Cessation
- 1996-12-27 JP JP52411697A patent/JP4160117B2/ja not_active Expired - Lifetime
- 1996-12-27 DE DE69623650T patent/DE69623650T2/de not_active Expired - Lifetime
- 1996-12-27 AU AU13847/97A patent/AU714953B2/en not_active Expired
- 1996-12-27 AT AT96944117T patent/ATE224050T1/de not_active IP Right Cessation
- 1996-12-27 WO PCT/GB1996/003257 patent/WO1997024601A1/en active IP Right Grant
- 1996-12-27 EP EP96944117A patent/EP0870187B1/de not_active Expired - Lifetime
- 1996-12-27 CA CA002240573A patent/CA2240573C/en not_active Expired - Lifetime
- 1996-12-27 US US09/101,013 patent/US6422065B1/en not_active Expired - Fee Related
- 1996-12-27 DE DE69635391T patent/DE69635391T2/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP1180678B1 (de) | 2005-11-02 |
EP0870187A1 (de) | 1998-10-14 |
EP1180678A3 (de) | 2004-01-14 |
US20020035879A1 (en) | 2002-03-28 |
DE69623650T2 (de) | 2003-02-13 |
ATE308746T1 (de) | 2005-11-15 |
US6422065B1 (en) | 2002-07-23 |
EP1180678A2 (de) | 2002-02-20 |
DE69635391D1 (de) | 2005-12-08 |
CA2240573A1 (en) | 1997-07-10 |
WO1997024601A1 (en) | 1997-07-10 |
CA2240573C (en) | 2004-11-09 |
AU1384797A (en) | 1997-07-28 |
ATE224050T1 (de) | 2002-09-15 |
AU714953B2 (en) | 2000-01-13 |
DE69635391T2 (de) | 2006-08-03 |
JP2000502797A (ja) | 2000-03-07 |
EP0870187B1 (de) | 2002-09-11 |
JP4160117B2 (ja) | 2008-10-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE153133T1 (de) | Verfahren und gerät zur messung von optischen eigenschaften biologischer proben | |
DE69623650D1 (de) | Verfahren zum testen einer zellprobe | |
DE69030733D1 (de) | Zweifarben Kamera Mikroskop sowie Methodologie zur Anfärben von Zellen sowie Analyse | |
DE69636947D1 (de) | Vorrichtung und Verfahren zum Markieren von vorbestimmten Ereignissen mit einem Biosensor | |
DE69629292D1 (de) | Verfahren zum feststellen der preparationsgüte von objektträgern und proben | |
DE50002552D1 (de) | Verfahren zur bearbeitung seismischer messdaten mit einem neuronalen netzwerk | |
DE69809046T2 (de) | Analytische Testvorrichtung und Verfahren zu ihrer Verwendung | |
DE60034370D1 (de) | Verfahren und vorrichtung zur analyse von zellen in einer vollblutprobe | |
WO2001011354A3 (en) | Methods for characterizing, classifying, and identifying unknowns in samples | |
DE59510540D1 (de) | Verfahren zur Ermittlung von Positionsdaten und Vorrichtung für das Messen der Vergrösserung in einem optischen Strahlengang | |
DE60121791D1 (de) | Elektrochemische zellen und verfahren und vorrichtung zur regulierung deren aufladung | |
DE69513054T2 (de) | Herstellungsverfahren einer elektrode für eine elektrochemische vorrichtung | |
ATE351900T1 (de) | Sonde, zelle und verfahren zur messung der konzentration und der zusammensetzung von biomasse | |
AT357133B (de) | Verfahren zur massenzuechtung von diploiden zellen und vorrichtung zu seiner durchfuehrung | |
DE60111124D1 (de) | Kollimatorvorrichtung, Röntgeneinrichtung, Testausrüstung, Verfahren zur Prüfung einer Röntgeneinrichtung, Computerprogramm zur Ausführung dieses Verfahrens und Speichermedium lesbar von einem Lesegerät für diesen Computerprogramm | |
DE68923283D1 (de) | Verfahren, prüfsonde und vorrichtung zur messung eines wechselsromspannungsabfalls. | |
ATE35693T1 (de) | Verfahren und vorrichtung zur identifizierung von mikroorganismen. | |
EP0595506A3 (de) | Automatische Detektion von kanzerogenem oder vorkanzerogenem Gewebe durch Messung maligner Veränderungen. | |
DE60229593D1 (de) | Verfahren zur Quantifizierung von Nukleinsäuren mittels Bestimmung der Zellzahl | |
WO2004078131A3 (en) | Evaluating effects of exposure conditions on drug samples over time | |
ATE123578T1 (de) | Vorrichtung und verfahren zur selbsttätigen rechnung der güte einer elektrischen wicklung. | |
JP3212560B2 (ja) | 皮膚角質細胞の染色方法 | |
JP2003315331A5 (de) | ||
DE59807515D1 (de) | Vorrichtung zur Erfassung von Parametern eines langgestreckten Prüfguts | |
ATE418725T1 (de) | Verfahren zur verifikation der verwendung eines bestimmten färbemittels für eine zellprobe |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |