DE69622708T2 - Impstoff gegen krebs, der mit il-6/il-6 rezeptor transfizierte zellen enthält - Google Patents

Impstoff gegen krebs, der mit il-6/il-6 rezeptor transfizierte zellen enthält

Info

Publication number
DE69622708T2
DE69622708T2 DE69622708T DE69622708T DE69622708T2 DE 69622708 T2 DE69622708 T2 DE 69622708T2 DE 69622708 T DE69622708 T DE 69622708T DE 69622708 T DE69622708 T DE 69622708T DE 69622708 T2 DE69622708 T2 DE 69622708T2
Authority
DE
Germany
Prior art keywords
receptor
cells transfected
containing cells
vaccine against
against cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69622708T
Other languages
English (en)
Other versions
DE69622708D1 (de
Inventor
Andrzej Mackiewicz
Stefan Rose-John
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AKADEMIA MEDYCZNA IM K MARCINK
Original Assignee
AKADEMIA MEDYCZNA IM K MARCINK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AKADEMIA MEDYCZNA IM K MARCINK filed Critical AKADEMIA MEDYCZNA IM K MARCINK
Application granted granted Critical
Publication of DE69622708D1 publication Critical patent/DE69622708D1/de
Publication of DE69622708T2 publication Critical patent/DE69622708T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001102—Receptors, cell surface antigens or cell surface determinants
    • A61K39/001116—Receptors for cytokines
    • A61K39/001119—Receptors for interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001136—Cytokines
    • A61K39/00114—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5412—IL-6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69622708T 1995-05-15 1996-05-13 Impstoff gegen krebs, der mit il-6/il-6 rezeptor transfizierte zellen enthält Expired - Lifetime DE69622708T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PL95308627A PL190445B1 (pl) 1995-05-15 1995-05-15 Genetyczna szczepionka przeciwrakowa
PCT/PL1996/000010 WO1996036354A2 (en) 1995-05-15 1996-05-13 Anticancer vaccine comprising il6/il6 receptor transfected cells

Publications (2)

Publication Number Publication Date
DE69622708D1 DE69622708D1 (de) 2002-09-05
DE69622708T2 true DE69622708T2 (de) 2002-11-14

Family

ID=20065039

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69622708T Expired - Lifetime DE69622708T2 (de) 1995-05-15 1996-05-13 Impstoff gegen krebs, der mit il-6/il-6 rezeptor transfizierte zellen enthält

Country Status (5)

Country Link
US (1) US5935569A (de)
EP (1) EP0825873B1 (de)
DE (1) DE69622708T2 (de)
PL (1) PL190445B1 (de)
WO (1) WO1996036354A2 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL122818A0 (en) 1997-07-10 1998-08-16 Yeda Res & Dev Chimeric interleukin-6 soluble receptor/ligand protein analogs thereof and uses thereof
DE10107737A1 (de) * 2001-02-16 2002-09-05 S Rose John Christian Albrecht Verwendung eines Konjugats aus IL-6 und einem IL-6 Rezeptor zur Tumortherapie
US8216585B2 (en) 2001-05-25 2012-07-10 The Trustees Of The University Of Pennsylvania Targeted particles and methods of using the same
WO2003092579A2 (en) * 2002-04-29 2003-11-13 Hadasit Medical Research Services And Development Company Ltd. Compositions and methods for treating cancer with an oncolytic viral agent

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL99821A (en) * 1991-10-22 1996-07-23 Yeda Res & Dev Antitumor vaccines comprising cells transfected with a gene encoding human il-6

Also Published As

Publication number Publication date
PL190445B1 (pl) 2005-12-30
PL308627A1 (en) 1996-11-25
DE69622708D1 (de) 2002-09-05
WO1996036354A2 (en) 1996-11-21
EP0825873A2 (de) 1998-03-04
EP0825873B1 (de) 2002-07-31
US5935569A (en) 1999-08-10
WO1996036354A3 (en) 1997-03-06

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Legal Events

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